malignant neoplasm of the central nervous system Gene Set
Genes
37 genes associated with the malignant neoplasm of the central nervous system phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.
| Symbol |
Name |
|
APC
|
adenomatous polyposis coli
|
|
ASCL1
|
achaete-scute family bHLH transcription factor 1
|
|
BDNF
|
brain-derived neurotrophic factor
|
|
BRAF
|
B-Raf proto-oncogene, serine/threonine kinase
|
|
CDKN2A
|
cyclin-dependent kinase inhibitor 2A
|
|
CHEK2
|
checkpoint kinase 2
|
|
DICER1
|
dicer 1, ribonuclease type III
|
|
EDN3
|
endothelin 3
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
|
GABRD
|
gamma-aminobutyric acid (GABA) A receptor, delta
|
|
GDNF
|
glial cell derived neurotrophic factor
|
|
GPC3
|
glypican 3
|
|
GPC4
|
glypican 4
|
|
KCNAB2
|
potassium channel, voltage gated subfamily A regulatory beta subunit 2
|
|
MLH1
|
mutL homolog 1
|
|
MSH2
|
mutS homolog 2
|
|
MSH6
|
mutS homolog 6
|
|
NBN
|
nibrin
|
|
NF1
|
neurofibromin 1
|
|
NF2
|
neurofibromin 2 (merlin)
|
|
NME1
|
NME/NM23 nucleoside diphosphate kinase 1
|
|
PALB2
|
partner and localizer of BRCA2
|
|
PHOX2B
|
paired-like homeobox 2b
|
|
PMS2
|
PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
|
|
PRDM16
|
PR domain containing 16
|
|
PTCH1
|
patched 1
|
|
PTCH2
|
patched 2
|
|
PTPN11
|
protein tyrosine phosphatase, non-receptor type 11
|
|
RAF1
|
Raf-1 proto-oncogene, serine/threonine kinase
|
|
RET
|
ret proto-oncogene
|
|
RUNX1
|
runt-related transcription factor 1
|
|
SDHB
|
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
|
|
SKI
|
SKI proto-oncogene
|
|
SMARCB1
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
|
|
SUFU
|
suppressor of fused homolog (Drosophila)
|
|
TSC1
|
tuberous sclerosis 1
|
|
TSC2
|
tuberous sclerosis 2
|
