mandible Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description 1: The lower jaw of a vertebrate animal. 2: Either the upper or lower part of the beak in birds. (BRENDA Tissue and Enzyme Source Ontology, BTO_0001748)
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Genes

384 proteins co-occuring with the tissue mandible in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
FANCL Fanconi anemia, complementation group L 2.18979
BMP2 bone morphogenetic protein 2 2.14906
NOTCH1 notch 1 2.03214
NT5M 5',3'-nucleotidase, mitochondrial 1.81634
SH3BP2 SH3-domain binding protein 2 1.79955
TMEM54 transmembrane protein 54 1.76676
ALPP alkaline phosphatase, placental 1.76074
ALPPL2 alkaline phosphatase, placental-like 2 1.71639
ALPL alkaline phosphatase, liver/bone/kidney 1.71539
CTNNBIP1 catenin, beta interacting protein 1 1.70644
SGOL1 shugoshin-like 1 (S. pombe) 1.68254
NANS N-acetylneuraminic acid synthase 1.59523
PTH parathyroid hormone 1.52999
COPG1 coatomer protein complex, subunit gamma 1 1.51855
BGLAP bone gamma-carboxyglutamate (gla) protein 1.51759
ACPP acid phosphatase, prostate 1.50244
MSX1 msh homeobox 1 1.432
BMP7 bone morphogenetic protein 7 1.41676
MUL1 mitochondrial E3 ubiquitin protein ligase 1 1.4163
BMP4 bone morphogenetic protein 4 1.38047
CDC73 cell division cycle 73 1.37636
ACAN aggrecan 1.34406
FDPS farnesyl diphosphate synthase 1.32732
RUNX2 runt-related transcription factor 2 1.29849
KLHL4 kelch-like family member 4 1.28906
SPP1 secreted phosphoprotein 1 1.28143
PGRMC1 progesterone receptor membrane component 1 1.202
NCOA1 nuclear receptor coactivator 1 1.17846
ERCC6 excision repair cross-complementation group 6 1.15894
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 1.15495
PTHLH parathyroid hormone-like hormone 1.14697
AMELX amelogenin, X-linked 1.14653
IHH indian hedgehog 1.13856
SOX9 SRY (sex determining region Y)-box 9 1.13767
PCNA proliferating cell nuclear antigen 1.13058
C9ORF3 chromosome 9 open reading frame 3 1.12527
AMELY amelogenin, Y-linked 1.12128
MSX2 msh homeobox 2 1.11995
BARX1 BARX homeobox 1 1.11597
PAX9 paired box 9 1.10579
IGF1 insulin-like growth factor 1 (somatomedin C) 1.10447
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 1.07706
EDARADD EDAR-associated death domain 1.07662
AMBN ameloblastin (enamel matrix protein) 1.06691
SP7 Sp7 transcription factor 1.05897
TGFB1 transforming growth factor, beta 1 1.05325
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma 1.05193
DLX5 distal-less homeobox 5 1.04269
IBSP integrin-binding sialoprotein 1.03083
CALCA calcitonin-related polypeptide alpha 1.02732
FGF2 fibroblast growth factor 2 (basic) 1.01943
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 1.01375
FGFR3 fibroblast growth factor receptor 3 0.99586
BGN biglycan 0.994119
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 0.978482
PERP PERP, TP53 apoptosis effector 0.967657
CKAP2 cytoskeleton associated protein 2 0.959449
FGF8 fibroblast growth factor 8 (androgen-induced) 0.95384
DLX6 distal-less homeobox 6 0.952116
MNX1 motor neuron and pancreas homeobox 1 0.944796
MMP8 matrix metallopeptidase 8 0.941785
TNC tenascin C 0.911373
KIZ kizuna centrosomal protein 0.90924
NBPF1 neuroblastoma breakpoint family, member 1 0.905831
FGFR1OP2 FGFR1 oncogene partner 2 0.885862
DSPP dentin sialophosphoprotein 0.880358
ENO2 enolase 2 (gamma, neuronal) 0.868529
LRTM1 leucine-rich repeats and transmembrane domains 1 0.867686
LMNA lamin A/C 0.862627
MEPE matrix extracellular phosphoglycoprotein 0.861785
NF1 neurofibromin 1 0.857153
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.856312
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 0.852948
TRIP12 thyroid hormone receptor interactor 12 0.847065
FN1 fibronectin 1 0.847065
PLCL1 phospholipase C-like 1 0.842447
TCOF1 Treacher Collins-Franceschetti syndrome 1 0.835737
HEBP1 heme binding protein 1 0.835737
SHH sonic hedgehog 0.828197
SBDS Shwachman-Bodian-Diamond syndrome 0.825686
HM13 histocompatibility (minor) 13 0.811056
SOST sclerostin 0.791044
C4ORF26 chromosome 4 open reading frame 26 0.786052
ZMPSTE24 zinc metallopeptidase STE24 0.77857
FAM120A family with sequence similarity 120A 0.773589
BLOC1S4 biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino 0.769855
CPXCR1 CPX chromosome region, candidate 1 0.766954
KAZALD1 Kazal-type serine peptidase inhibitor domain 1 0.764054
TWSG1 twisted gastrulation BMP signaling modulator 1 0.762397
ENAM enamelin 0.745451
VCAN versican 0.737618
CTSK cathepsin K 0.734323
FGFR2 fibroblast growth factor receptor 2 0.731854
HAND2 heart and neural crest derivatives expressed 2 0.731854
COL1A1 collagen, type I, alpha 1 0.72733
GSC goosecoid homeobox 0.725274
PLCB4 phospholipase C, beta 4 0.725274
MMP13 matrix metallopeptidase 13 0.717472
CD68 CD68 molecule 0.713779
OMD osteomodulin 0.71009
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.70968
OGN osteoglycin 0.706812
MGAM maltase-glucoamylase 0.700671
PRG4 proteoglycan 4 0.700671
PTER phosphotriesterase related 0.700262
SUN1 Sad1 and UNC84 domain containing 1 0.692902
PITX2 paired-like homeodomain 2 0.692493
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.67495
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal 0.667215
MMD monocyte to macrophage differentiation-associated 0.652994
COL2A1 collagen, type II, alpha 1 0.65056
FUZ fuzzy planar cell polarity protein 0.63638
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.635976
WRNIP1 Werner helicase interacting protein 1 0.630718
LRP5 low density lipoprotein receptor-related protein 5 0.62991
GNAS GNAS complex locus 0.627889
AMTN amelotin 0.612555
ERCC8 excision repair cross-complementation group 8 0.606112
KRT14 keratin 14, type I 0.604502
KRT19 keratin 19, type I 0.602088
LECT1 leukocyte cell derived chemotaxin 1 0.598067
NKX2-6 NK2 homeobox 6 0.595255
HBA2 hemoglobin, alpha 2 0.594451
PRRX1 paired related homeobox 1 0.592444
KCTD11 potassium channel tetramerization domain containing 11 0.588832
MGP matrix Gla protein 0.584022
CRELD1 cysteine-rich with EGF-like domains 1 0.58322
NOG noggin 0.578016
LCORL ligand dependent nuclear receptor corepressor-like 0.576015
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 0.574017
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic 0.570021
MMP1 matrix metallopeptidase 1 0.56603
PSG6 pregnancy specific beta-1-glycoprotein 6 0.564035
TMEM26 transmembrane protein 26 0.562441
ESM1 endothelial cell-specific molecule 1 0.559652
F8 coagulation factor VIII, procoagulant component 0.552888
SPAG1 sperm associated antigen 1 0.549709
DCN decorin 0.548517
DLX3 distal-less homeobox 3 0.540585
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 0.52556
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 0.52556
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) 0.521223
PRTG protogenin 0.519253
TIMP1 TIMP metallopeptidase inhibitor 1 0.519253
WDR72 WD repeat domain 72 0.509813
NUMB numb homolog (Drosophila) 0.508635
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 0.507457
SOX5 SRY (sex determining region Y)-box 5 0.507064
VEGFB vascular endothelial growth factor B 0.504318
TRIM47 tripartite motif containing 47 0.503141
P3H2 prolyl 3-hydroxylase 2 0.502357
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 0.501965
CD34 CD34 molecule 0.501965
FOXI1 forkhead box I1 0.494918
TUFT1 tuftelin 1 0.494528
TP53 tumor protein p53 0.493354
SOS1 son of sevenless homolog 1 (Drosophila) 0.490619
KMT2A lysine (K)-specific methyltransferase 2A 0.488667
NAT9 N-acetyltransferase 9 (GCN5-related, putative) 0.488276
ALX4 ALX homeobox 4 0.486326
WNT1 wingless-type MMTV integration site family, member 1 0.485156
MMP3 matrix metallopeptidase 3 0.485156
DUX4L9 double homeobox 4 like 9 0.484766
DUX4L4 double homeobox 4 like 4 0.484766
CLCN7 chloride channel, voltage-sensitive 7 0.484376
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 0.483206
PTH1R parathyroid hormone 1 receptor 0.482428
RPL21 ribosomal protein L21 0.477367
COPA coatomer protein complex, subunit alpha 0.476979
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.476589
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 0.475034
PHF20 PHD finger protein 20 0.461465
CPLX3 complexin 3 0.461078
KCTD5 potassium channel tetramerization domain containing 5 0.461078
NCAPG non-SMC condensin I complex, subunit G 0.459145
SPRY3 sprouty homolog 3 (Drosophila) 0.456442
IGF1R insulin-like growth factor 1 receptor 0.45567
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 0.45567
HPD 4-hydroxyphenylpyruvate dioxygenase 0.454512
CROT carnitine O-octanoyltransferase 0.454512
JAG2 jagged 2 0.452584
CTGF connective tissue growth factor 0.452198
ZIC5 Zic family member 5 0.449501
MMP9 matrix metallopeptidase 9 0.448731
FGF7 fibroblast growth factor 7 0.446422
HTRA2 HtrA serine peptidase 2 0.442962
RPIA ribose 5-phosphate isomerase A 0.442578
PTGFRN prostaglandin F2 receptor inhibitor 0.43989
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.436055
MID1 midline 1 0.432608
EIF4A3 eukaryotic translation initiation factor 4A3 0.429165
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled 0.426872
PDGFB platelet-derived growth factor beta polypeptide 0.42649
LTBP3 latent transforming growth factor beta binding protein 3 0.42649
FGFR1 fibroblast growth factor receptor 1 0.423054
PNN pinin, desmosome associated protein 0.423054
GHR growth hormone receptor 0.421148
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.41848
HBA1 hemoglobin, alpha 1 0.416576
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.416195
LHX6 LIM homeobox 6 0.414673
LTBP2 latent transforming growth factor beta binding protein 2 0.413912
VEGFA vascular endothelial growth factor A 0.413532
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.412391
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 0.410491
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.410491
FMOD fibromodulin 0.40328
FGF17 fibroblast growth factor 17 0.401765
EXT1 exostosin glycosyltransferase 1 0.398357
NXT1 nuclear transport factor 2-like export factor 1 0.396465
VPREB1 pre-B lymphocyte 1 0.396087
GPD1L glycerol-3-phosphate dehydrogenase 1-like 0.391553
RIMS2 regulating synaptic membrane exocytosis 2 0.391176
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 0.391176
PITX1 paired-like homeodomain 1 0.390044
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 0.38439
MKX mohawk homeobox 0.384013
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein 0.383637
MYH1 myosin, heavy chain 1, skeletal muscle, adult 0.38326
FHL1 four and a half LIM domains 1 0.377621
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 0.377621
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.377621
KRT8 keratin 8, type II 0.37687
KLRC3 killer cell lectin-like receptor subfamily C, member 3 0.375368
IGF2-AS IGF2 antisense RNA 0.36825
PAPPA2 pappalysin 2 0.36526
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 0.363766
EDA ectodysplasin A 0.362646
MARS methionyl-tRNA synthetase 0.358546
PRSS21 protease, serine, 21 (testisin) 0.358174
ITM2B integral membrane protein 2B 0.355198
ANO1 anoctamin 1, calcium activated chloride channel 0.354455
ITM2A integral membrane protein 2A 0.354455
KRT75 keratin 75, type II 0.353712
MATN1 matrilin 1, cartilage matrix protein 0.351856
DPP7 dipeptidyl-peptidase 7 0.351485
FGF1 fibroblast growth factor 1 (acidic) 0.351114
PIGY phosphatidylinositol glycan anchor biosynthesis, class Y 0.351114
LAX1 lymphocyte transmembrane adaptor 1 0.34963
SPRY2 sprouty homolog 2 (Drosophila) 0.34963
SATB2 SATB homeobox 2 0.345928
GLMN glomulin, FKBP associated protein 0.344818
HOXA2 homeobox A2 0.344449
GREM2 gremlin 2, DAN family BMP antagonist 0.341495
GLDN gliomedin 0.340388
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 0.33965
GDF5 growth differentiation factor 5 0.33965
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 0.336336
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 0.335968
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 0.335968
HHAT hedgehog acyltransferase 0.333763
HOPX HOP homeobox 0.332294
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 0.329727
RNF7 ring finger protein 7 0.328262
DLX1 distal-less homeobox 1 0.327164
DPH1 diphthamide biosynthesis 1 0.322779
TGFB3 transforming growth factor, beta 3 0.32132
TGFB2 transforming growth factor, beta 2 0.318042
CHURC1 churchill domain containing 1 0.315861
ADIG adipogenin 0.314409
SCUBE1 signal peptide, CUB domain, EGF-like 1 0.310059
COPB2 coatomer protein complex, subunit beta 2 (beta prime) 0.309697
WIPF2 WAS/WASL interacting protein family, member 2 0.308974
MMP2 matrix metallopeptidase 2 0.308251
MPG N-methylpurine-DNA glycosylase 0.307889
RCE1 Ras converting CAAX endopeptidase 1 0.305722
DEFB105B defensin, beta 105B 0.30464
TIMP3 TIMP metallopeptidase inhibitor 3 0.30464
ESR1 estrogen receptor 1 0.302118
TBX22 T-box 22 0.301758
SETD1A SET domain containing 1A 0.29996
IDUA iduronidase, alpha-L- 0.299002
GPS2 G protein pathway suppressor 2 0.298524
CSN1S1 casein alpha s1 0.29673
NUCLEOLIN nucleolin multifunctional protein 0.295297
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.295297
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 0.295297
SLURP1 secreted LY6/PLAUR domain containing 1 0.294939
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 0.294581
TWIST1 twist family bHLH transcription factor 1 0.293151
COL10A1 collagen, type X, alpha 1 0.291365
ACVR1 activin A receptor, type I 0.290295
IL1B interleukin 1, beta 0.289226
ZFAT zinc finger and AT hook domain containing 0.285671
TGFA transforming growth factor, alpha 0.285316
INS insulin 0.283191
LIN9 lin-9 DREAM MuvB core complex component 0.280717
USH1G Usher syndrome 1G (autosomal recessive) 0.277549
MMP20 matrix metallopeptidase 20 0.275444
SVIL supervillin 0.275444
REG1B regenerating islet-derived 1 beta 0.274394
BIN3 bridging integrator 3 0.274394
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 0.274045
NELL1 NEL-like 1 (chicken) 0.273463
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 0.272997
PTCH1 patched 1 0.271256
SMAD2 SMAD family member 2 0.270909
TMX1 thioredoxin-related transmembrane protein 1 0.270561
CADM1 cell adhesion molecule 1 0.268482
SACK1H scaffolding CK1 anchoring protein H 0.267791
ACSL1 acyl-CoA synthetase long-chain family member 1 0.262304
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker) 0.260945
BICD1 bicaudal D homolog 1 (Drosophila) 0.259591
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.25858
NKX2-3 NK2 homeobox 3 0.257907
BMP3 bone morphogenetic protein 3 0.256234
EWSR1 EWS RNA-binding protein 1 0.254239
KRT7 keratin 7, type II 0.25259
COL1A2 collagen, type I, alpha 2 0.251934
ALB albumin 0.251934
MEOX1 mesenchyme homeobox 1 0.250627
MRPL49 mitochondrial ribosomal protein L49 0.25041
TNMD tenomodulin 0.249329
CHD3 chromodomain helicase DNA binding protein 3 0.247079
CALCR calcitonin receptor 0.24676
MSTN myostatin 0.24676
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 0.245175
HAND1 heart and neural crest derivatives expressed 1 0.243918
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 0.242672
IFNE interferon, epsilon 0.241438
GSN gelsolin 0.241438
ADSL adenylosuccinate lyase 0.240216
OSTM1 osteopetrosis associated transmembrane protein 1 0.239913
ACPT acid phosphatase, testicular 0.23961
FMN2 formin 2 0.236921
EDN1 endothelin 1 0.236921
TENM1 teneurin transmembrane protein 1 0.236627
RAB4A RAB4A, member RAS oncogene family 0.236332
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.23604
LIF leukemia inhibitory factor 0.235457
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.234302
PDLIM1 PDZ and LIM domain 1 0.232317
ODAM odontogenic, ameloblast asssociated 0.23176
CXCL14 chemokine (C-X-C motif) ligand 14 0.228764
SPON2 spondin 2, extracellular matrix protein 0.227445
FGG fibrinogen gamma chain 0.226667
TNXA tenascin XA (pseudogene) 0.223825
TNXB tenascin XB 0.223743
SYP synaptophysin 0.223419
RSPO2 R-spondin 2 0.222224
SUGP1 SURP and G patch domain containing 1 0.221291
OPA1 optic atrophy 1 (autosomal dominant) 0.221291
EHD1 EH-domain containing 1 0.219928
DDO D-aspartate oxidase 0.218115
NGF nerve growth factor (beta polypeptide) 0.217762
MRAP melanocortin 2 receptor accessory protein 0.21673
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.216325
FXR2 fragile X mental retardation, autosomal homolog 2 0.216325
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 0.216126
PER2 period circadian clock 2 0.214954
GBA glucosidase, beta, acid 0.214576
TWIST2 twist family bHLH transcription factor 2 0.213895
TGFBR1 transforming growth factor, beta receptor 1 0.213833
SMCP sperm mitochondria-associated cysteine-rich protein 0.213833
FGF13 fibroblast growth factor 13 0.213833
ONECUT3 one cut homeobox 3 0.21365
DLK1 delta-like 1 homolog (Drosophila) 0.213471
APOC1 apolipoprotein C-I 0.213231
ESR2 estrogen receptor 2 (ER beta) 0.213231
NOTCH3 notch 3 0.212936
BMX BMX non-receptor tyrosine kinase 0.212877
AQP3 aquaporin 3 (Gill blood group) 0.211571
DYNLT1 dynein, light chain, Tctex-type 1 0.203992
EGLN3 egl-9 family hypoxia-inducible factor 3 0.202883
BIN1 bridging integrator 1 0.202524
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 0.200434
UGDH UDP-glucose 6-dehydrogenase 0.199975
MCM8 minichromosome maintenance complex component 8 0.199918
NOTCH4 notch 4 0.199348
JUNB jun B proto-oncogene 0.197602
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.197229
DKK3 dickkopf WNT signaling pathway inhibitor 3 0.197032
IL1A interleukin 1, alpha 0.196279
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 0.196109
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 0.19402
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 0.193227
NR2F6 nuclear receptor subfamily 2, group F, member 6 0.192591
TPR translocated promoter region, nuclear basket protein 0.191987
GALNS galactosamine (N-acetyl)-6-sulfatase 0.188226
CCL15 chemokine (C-C motif) ligand 15 0.186411
MAP2K4 mitogen-activated protein kinase kinase 4 0.180793
FXYD1 FXYD domain containing ion transport regulator 1 0.180317
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.179917
TGFBI transforming growth factor, beta-induced, 68kDa 0.179665