mantle zone of the PBC Gene Set

Dataset Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles
Category transcriptomics
Type tissue
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Genes

269 genes with high or low expression in mantle zone of the PBC relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
H2BFM H2B histone family, member M 2.16531
ITGA8 integrin, alpha 8 2.14054
IL12A interleukin 12A 1.99326
FAM120C family with sequence similarity 120C 1.97903
S100A13 S100 calcium binding protein A13 1.96934
CCDC17 coiled-coil domain containing 17 1.82021
ZCCHC4 zinc finger, CCHC domain containing 4 1.79914
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 1.78813
C8G complement component 8, gamma polypeptide 1.78654
KRT39 keratin 39, type I 1.75522
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 1.71387
STBD1 starch binding domain 1 1.66858
PAX5 paired box 5 1.62049
TAMM41 TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae) 1.61655
BTNL9 butyrophilin-like 9 1.58096
HMGCLL1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 1.52471
TMEM117 transmembrane protein 117 1.49486
MYO1E myosin IE 1.48445
RPGRIP1L RPGRIP1-like 1.48261
FAM47A family with sequence similarity 47, member A 1.43218
ASGR2 asialoglycoprotein receptor 2 1.41368
CRYGB crystallin, gamma B 1.39971
TTC16 tetratricopeptide repeat domain 16 1.39497
DNHD1 dynein heavy chain domain 1 1.39488
OCRL oculocerebrorenal syndrome of Lowe 1.39073
SCRT2 scratch family zinc finger 2 1.38253
PHF1 PHD finger protein 1 1.3791
PPAPDC1A phosphatidic acid phosphatase type 2 domain containing 1A 1.3673
KIAA1033 KIAA1033 1.36495
SMAD9 SMAD family member 9 1.35983
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 1.35481
UGT2A2 UDP glucuronosyltransferase 2 family, polypeptide A2 1.35289
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 1.35026
RWDD2A RWD domain containing 2A 1.34517
SPX spexin hormone 1.33703
METTL16 methyltransferase like 16 1.33289
OPTC opticin 1.30979
FTO fat mass and obesity associated 1.2977
CERS1 ceramide synthase 1 1.29753
SIMC1 SUMO-interacting motifs containing 1 1.2973
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 1.29675
LRRC43 leucine rich repeat containing 43 1.29536
MNX1 motor neuron and pancreas homeobox 1 1.28256
RPS4Y1 ribosomal protein S4, Y-linked 1 1.28063
WDPCP WD repeat containing planar cell polarity effector 1.27916
TTLL10 tubulin tyrosine ligase-like family member 10 1.27842
USP35 ubiquitin specific peptidase 35 1.27182
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 1.26031
HPSE heparanase 1.26012
MSANTD1 Myb/SANT-like DNA-binding domain containing 1 1.24554
HIGD1A HIG1 hypoxia inducible domain family, member 1A 1.23177
CCL28 chemokine (C-C motif) ligand 28 1.22926
DRD5 dopamine receptor D5 1.22276
HTRA4 HtrA serine peptidase 4 1.21426
RPS8 ribosomal protein S8 1.1987
AMIGO3 adhesion molecule with Ig-like domain 3 1.19596
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.19455
TSEN15 TSEN15 tRNA splicing endonuclease subunit 1.19079
NT5C1A 5'-nucleotidase, cytosolic IA 1.18939
RPS18 ribosomal protein S18 1.17966
WDR54 WD repeat domain 54 1.16748
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 1.16524
RGS17 regulator of G-protein signaling 17 1.16142
SQLE squalene epoxidase 1.15695
SETD1A SET domain containing 1A 1.15434
CYTH4 cytohesin 4 1.15211
PCM1 pericentriolar material 1 1.15143
LARP4 La ribonucleoprotein domain family, member 4 1.14946
C21ORF2 chromosome 21 open reading frame 2 1.14561
C1ORF112 chromosome 1 open reading frame 112 1.14416
ZNF688 zinc finger protein 688 1.14054
BBS9 Bardet-Biedl syndrome 9 1.14041
TTC21A tetratricopeptide repeat domain 21A 1.13924
CYSRT1 cysteine-rich tail protein 1 1.13821
APOH apolipoprotein H (beta-2-glycoprotein I) 1.1368
PCDHGC4 protocadherin gamma subfamily C, 4 1.1367
FEN1 flap structure-specific endonuclease 1 1.13603
CFDP1 craniofacial development protein 1 1.13366
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 1.13229
AIDA axin interactor, dorsalization associated 1.1259
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 1.1182
C19ORF40 chromosome 19 open reading frame 40 1.11632
CBFB core-binding factor, beta subunit 1.10395
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 1.10354
C2ORF54 chromosome 2 open reading frame 54 1.10308
PCSK6 proprotein convertase subtilisin/kexin type 6 1.10114
CYTH3 cytohesin 3 1.10109
POGLUT1 protein O-glucosyltransferase 1 1.09828
SH2D6 SH2 domain containing 6 1.09251
IFT43 intraflagellar transport 43 1.08966
MCOLN3 mucolipin 3 1.08899
GJD3 gap junction protein, delta 3, 31.9kDa 1.08665
TTC1 tetratricopeptide repeat domain 1 1.082
HNRNPR heterogeneous nuclear ribonucleoprotein R 1.07942
PDRG1 p53 and DNA-damage regulated 1 1.07548
TCP11X2 t-complex 11 family, X-linked 2 1.07303
PTH parathyroid hormone 1.0712
KCNK5 potassium channel, two pore domain subfamily K, member 5 1.06954
RTKN2 rhotekin 2 1.06369
DUSP27 dual specificity phosphatase 27 (putative) 1.06342
C6ORF163 chromosome 6 open reading frame 163 1.06182
PEG3 paternally expressed 3 1.06161
NAE1 NEDD8 activating enzyme E1 subunit 1 1.06034
DNAI2 dynein, axonemal, intermediate chain 2 1.0603
TMX4 thioredoxin-related transmembrane protein 4 1.05469
IRX4 iroquois homeobox 4 1.05273
B3GALNT2 beta-1,3-N-acetylgalactosaminyltransferase 2 1.04764
RPAIN RPA interacting protein 1.04744
EN1 engrailed homeobox 1 1.04407
EPHB1 EPH receptor B1 1.04272
FIGNL1 fidgetin-like 1 1.03784
EYA3 EYA transcriptional coactivator and phosphatase 3 1.02596
JAG2 jagged 2 1.02145
AFF4 AF4/FMR2 family, member 4 1.02
KIF16B kinesin family member 16B 1.01977
PAQR6 progestin and adipoQ receptor family member VI 1.01329
DUSP22 dual specificity phosphatase 22 1.01284
RPS26 ribosomal protein S26 1.00651
B3GNT5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 1.00463
FCHSD1 FCH and double SH3 domains 1 1.00429
CALCB calcitonin-related polypeptide beta 1.00346

low expression

Symbol Name Standardized Value
MAGT1 magnesium transporter 1 -2.09912
TMEM160 transmembrane protein 160 -1.96044
A3GALT2 alpha 1,3-galactosyltransferase 2 -1.90436
ZDHHC4 zinc finger, DHHC-type containing 4 -1.86762
ARL14 ADP-ribosylation factor-like 14 -1.81509
SERP1 stress-associated endoplasmic reticulum protein 1 -1.75498
OR2T6 olfactory receptor, family 2, subfamily T, member 6 -1.74246
EMCN endomucin -1.733
TAPBPL TAP binding protein-like -1.72323
CLEC4G C-type lectin domain family 4, member G -1.67281
MKRN1 makorin ring finger protein 1 -1.65993
NDC80 NDC80 kinetochore complex component -1.6541
CABP2 calcium binding protein 2 -1.62996
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 -1.62429
DEFB116 defensin, beta 116 -1.61837
MPG N-methylpurine-DNA glycosylase -1.6167
TGM6 transglutaminase 6 -1.59729
LTF lactotransferrin -1.59067
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) -1.5824
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 -1.5765
EBP emopamil binding protein (sterol isomerase) -1.57004
NARFL nuclear prelamin A recognition factor-like -1.50961
RFC4 replication factor C (activator 1) 4, 37kDa -1.4819
ANXA13 annexin A13 -1.46544
CINP cyclin-dependent kinase 2 interacting protein -1.44401
EEFSEC eukaryotic elongation factor, selenocysteine-tRNA-specific -1.44341
SETDB2 SET domain, bifurcated 2 -1.43911
C14ORF39 chromosome 14 open reading frame 39 -1.43699
STMND1 stathmin domain containing 1 -1.43548
PPEF2 protein phosphatase, EF-hand calcium binding domain 2 -1.42703
WDR86 WD repeat domain 86 -1.42619
C1QTNF7 C1q and tumor necrosis factor related protein 7 -1.40114
L3HYPDH L-3-hydroxyproline dehydratase (trans-) -1.40008
SECTM1 secreted and transmembrane 1 -1.39774
ARHGAP30 Rho GTPase activating protein 30 -1.39595
ARL15 ADP-ribosylation factor-like 15 -1.38962
CLDN6 claudin 6 -1.38774
TWF2 twinfilin actin binding protein 2 -1.37847
CCDC182 coiled-coil domain containing 182 -1.37831
WBSCR16 Williams-Beuren syndrome chromosome region 16 -1.37106
EFCAB7 EF-hand calcium binding domain 7 -1.35351
PIGW phosphatidylinositol glycan anchor biosynthesis, class W -1.35315
FAM45A family with sequence similarity 45, member A -1.35216
ADAM21 ADAM metallopeptidase domain 21 -1.34728
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa -1.33047
CCS copper chaperone for superoxide dismutase -1.32524
KRT8 keratin 8, type II -1.32157
OR4C45 olfactory receptor, family 4, subfamily C, member 45 -1.32049
PLEK pleckstrin -1.31545
KLRG1 killer cell lectin-like receptor subfamily G, member 1 -1.31221
THPO thrombopoietin -1.30944
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) -1.2992
SURF6 surfeit 6 -1.28851
CXCL17 chemokine (C-X-C motif) ligand 17 -1.28445
SEC63 SEC63 homolog (S. cerevisiae) -1.28287
HGFAC HGF activator -1.27903
AZIN1 antizyme inhibitor 1 -1.27501
ACOT8 acyl-CoA thioesterase 8 -1.2749
ZNF616 zinc finger protein 616 -1.27275
TRIB3 tribbles pseudokinase 3 -1.26846
PRRX1 paired related homeobox 1 -1.26675
ZNF623 zinc finger protein 623 -1.26536
FTCD formimidoyltransferase cyclodeaminase -1.26065
PRDM9 PR domain containing 9 -1.25834
SOCS6 suppressor of cytokine signaling 6 -1.25778
AP5M1 adaptor-related protein complex 5, mu 1 subunit -1.25724
TNFAIP8L1 tumor necrosis factor, alpha-induced protein 8-like 1 -1.25595
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic -1.24291
EAF2 ELL associated factor 2 -1.24235
GP6 glycoprotein VI (platelet) -1.24033
HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 -1.23709
OR56A3 olfactory receptor, family 56, subfamily A, member 3 -1.22846
TMEM248 transmembrane protein 248 -1.22825
FANCE Fanconi anemia, complementation group E -1.21599
CENPO centromere protein O -1.21519
PATE2 prostate and testis expressed 2 -1.2133
RNF224 ring finger protein 224 -1.21246
ALG9 ALG9, alpha-1,2-mannosyltransferase -1.21238
ZNF507 zinc finger protein 507 -1.20733
RPL3L ribosomal protein L3-like -1.20647
TRPM6 transient receptor potential cation channel, subfamily M, member 6 -1.20516
BLOC1S3 biogenesis of lysosomal organelles complex-1, subunit 3 -1.20372
TMEM241 transmembrane protein 241 -1.20126
HYAL3 hyaluronoglucosaminidase 3 -1.20031
KRT15 keratin 15, type I -1.199
KDF1 keratinocyte differentiation factor 1 -1.19638
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa -1.19375
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) -1.18848
TOP3B topoisomerase (DNA) III beta -1.18791
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 -1.18041
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 -1.17785
PAH phenylalanine hydroxylase -1.17418
DHFR dihydrofolate reductase -1.17269
FAM198A family with sequence similarity 198, member A -1.17072
RAD51AP1 RAD51 associated protein 1 -1.16706
CCDC79 coiled-coil domain containing 79 -1.16294
WDR36 WD repeat domain 36 -1.16018
ERCC8 excision repair cross-complementation group 8 -1.15738
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 -1.15666
GBP7 guanylate binding protein 7 -1.15474
TRAM2 translocation associated membrane protein 2 -1.15473
GALC galactosylceramidase -1.15465
DDN dendrin -1.1533
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 -1.14247
NPBWR1 neuropeptides B/W receptor 1 -1.1408
NUP155 nucleoporin 155kDa -1.13704
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 -1.13138
IL18BP interleukin 18 binding protein -1.12641
SPRYD4 SPRY domain containing 4 -1.11845
ATAD2 ATPase family, AAA domain containing 2 -1.11724
LMO7 LIM domain 7 -1.1138
ATP10B ATPase, class V, type 10B -1.11354
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 -1.1127
NMT2 N-myristoyltransferase 2 -1.11146
XKR8 XK, Kell blood group complex subunit-related family, member 8 -1.10992
C11ORF94 chromosome 11 open reading frame 94 -1.10532
CTSK cathepsin K -1.10286
FANCB Fanconi anemia, complementation group B -1.10149
GNRHR gonadotropin-releasing hormone receptor -1.09926
MESP1 mesoderm posterior basic helix-loop-helix transcription factor 1 -1.09728
UGT3A1 UDP glycosyltransferase 3 family, polypeptide A1 -1.09071
NEURL4 neuralized E3 ubiquitin protein ligase 4 -1.08197
TICAM1 toll-like receptor adaptor molecule 1 -1.07757
INMT indolethylamine N-methyltransferase -1.07728
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -1.07502
DMBT1 deleted in malignant brain tumors 1 -1.06309
NEURL2 neuralized E3 ubiquitin protein ligase 2 -1.06209
ISY1-RAB43 ISY1-RAB43 readthrough -1.05147
APOPT1 apoptogenic 1, mitochondrial -1.05036
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase -1.04364
ERN2 endoplasmic reticulum to nucleus signaling 2 -1.03716
IL6R interleukin 6 receptor -1.03684
ZPLD1 zona pellucida-like domain containing 1 -1.03575
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit -1.03366
CCDC115 coiled-coil domain containing 115 -1.03202
OR2T1 olfactory receptor, family 2, subfamily T, member 1 -1.03012
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -1.02944
ADAM11 ADAM metallopeptidase domain 11 -1.02705
HAO2 hydroxyacid oxidase 2 (long chain) -1.02476
LBR lamin B receptor -1.02294
CFAP74 cilia and flagella associated protein 74 -1.01689
CD226 CD226 molecule -1.01541
ZBED3 zinc finger, BED-type containing 3 -1.0111
ARHGAP25 Rho GTPase activating protein 25 -1.00914
ALPI alkaline phosphatase, intestinal -1.00833
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial -1.00622
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa -1.00387
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled -1.00367