mantle Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A fold or lobe or pair of lobes of the body wall of a mollusk or brachiopod that in shell-bearing forms lines the shell and bears shell-secreting glands. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000825)
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Genes

102 genes co-occuring with the biological term mantle in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ADAM10 ADAM metallopeptidase domain 10
AICDA activation-induced cytidine deaminase
AKT1 v-akt murine thymoma viral oncogene homolog 1
ATM ATM serine/threonine kinase
AURKA aurora kinase A
AURKB aurora kinase B
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BMI1 BMI1 proto-oncogene, polycomb ring finger
BMP7 bone morphogenetic protein 7
BTK Bruton agammaglobulinemia tyrosine kinase
CCDC50 coiled-coil domain containing 50
CCL19 chemokine (C-C motif) ligand 19
CCND1 cyclin D1
CCND2 cyclin D2
CCND3 cyclin D3
CD160 CD160 molecule
CD274 CD274 molecule
CD5 CD5 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDK4 cyclin-dependent kinase 4
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CKS1B CDC28 protein kinase regulatory subunit 1B
CNR1 cannabinoid receptor 1 (brain)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR4 chemokine (C-X-C motif) receptor 4
CXCR5 chemokine (C-X-C motif) receptor 5
DPP4 dipeptidyl-peptidase 4
FBXO25 F-box protein 25
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FMOD fibromodulin
FOXO3 forkhead box O3
GLI1 GLI family zinc finger 1
GSK3B glycogen synthase kinase 3 beta
GSTP1 glutathione S-transferase pi 1
HAX1 HCLS1 associated protein X-1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
IGF1R insulin-like growth factor 1 receptor
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL10 interleukin 10
IL12A interleukin 12A
IL12B interleukin 12B
IL6 interleukin 6
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
MAOA monoamine oxidase A
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MIR16-1 microRNA 16-1
MIR16-2 microRNA 16-2
MIR17 microRNA 17
MIR20A microRNA 20a
MKI67 marker of proliferation Ki-67
MLH1 mutL homolog 1
MME membrane metallo-endopeptidase
MTAP methylthioadenosine phosphorylase
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NOTCH1 notch 1
PARP1 poly (ADP-ribose) polymerase 1
PDE7B phosphodiesterase 7B
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
PRDM1 PR domain containing 1, with ZNF domain
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKCD protein kinase C, delta
PTPRJ protein tyrosine phosphatase, receptor type, J
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RB1 retinoblastoma 1
RGS13 regulator of G-protein signaling 13
ROR1 receptor tyrosine kinase-like orphan receptor 1
RRM2 ribonucleotide reductase M2
S1PR1 sphingosine-1-phosphate receptor 1
SHH sonic hedgehog
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SOCS3 suppressor of cytokine signaling 3
SOX11 SRY (sex determining region Y)-box 11
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SUZ12 SUZ12 polycomb repressive complex 2 subunit
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TTK TTK protein kinase
UBR5 ubiquitin protein ligase E3 component n-recognin 5
VEGFA vascular endothelial growth factor A
WNT10A wingless-type MMTV integration site family, member 10A
WNT3 wingless-type MMTV integration site family, member 3
XPO1 exportin 1