mantle Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description A fold or lobe or pair of lobes of the body wall of a mollusk or brachiopod that in shell-bearing forms lines the shell and bears shell-secreting glands. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000825)
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Genes

373 proteins co-occuring with the tissue mantle in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) 3.24742
CCND1 cyclin D1 2.16285
CD5 CD5 molecule 2.10272
MGAM maltase-glucoamylase 1.69799
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2 1.67256
CRNN cornulin 1.67106
BCL6 B-cell CLL/lymphoma 6 1.64156
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 1.52903
CD22 CD22 molecule 1.40892
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 1.38825
SOX11 SRY (sex determining region Y)-box 11 1.37408
PHYH phytanoyl-CoA 2-hydroxylase 1.33003
HEBP1 heme binding protein 1 1.30298
CD19 CD19 molecule 1.25994
BCL2 B-cell CLL/lymphoma 2 1.24074
FUCA1 fucosidase, alpha-L- 1, tissue 1.16737
CD38 CD38 molecule 1.11022
ISL1 ISL LIM homeobox 1 1.08325
PPY pancreatic polypeptide 1.07176
IGHV4-39 immunoglobulin heavy variable 4-39 1.05149
HYLS1 hydrolethalus syndrome 1 1.04885
GCG glucagon 1.03214
ARTN artemin 1.02469
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.992379
NUB1 negative regulator of ubiquitin-like proteins 1 0.991509
IGHV5-51 immunoglobulin heavy variable 5-51 0.989335
SOWAHA sosondowah ankyrin repeat domain family member A 0.977616
LITAF lipopolysaccharide-induced TNF factor 0.945226
CXCR5 chemokine (C-X-C motif) receptor 5 0.937488
IGHV4-34 immunoglobulin heavy variable 4-34 0.934482
SST somatostatin 0.931908
TP53 tumor protein p53 0.92291
ZSWIM5 zinc finger, SWIM-type containing 5 0.922055
FAS Fas cell surface death receptor 0.917779
SOX12 SRY (sex determining region Y)-box 12 0.907535
FCRL4 Fc receptor-like 4 0.901573
PCGF6 polycomb group ring finger 6 0.899445
B3GAT1 beta-1,3-glucuronyltransferase 1 0.881627
CD79B CD79b molecule, immunoglobulin-associated beta 0.879089
GSX2 GS homeobox 2 0.878243
TCL1A T-cell leukemia/lymphoma 1A 0.862627
LYZ lysozyme 0.85505
CDH4 cadherin 4, type 1, R-cadherin (retinal) 0.85505
SETMAR SET domain and mariner transposase fusion gene 0.853368
MBIP MAP3K12 binding inhibitory protein 1 0.834899
LYPLA1 lysophospholipase I 0.834061
BCL10 B-cell CLL/lymphoma 10 0.798125
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 0.794792
SLC22A16 solute carrier family 22 (organic cation/carnitine transporter), member 16 0.791044
ALPP alkaline phosphatase, placental 0.790628
CTSC cathepsin C 0.762397
NKX2-2 NK2 homeobox 2 0.761984
C5ORF49 chromosome 5 open reading frame 49 0.754124
ADGRG3 adhesion G protein-coupled receptor G3 0.753297
CD4 CD4 molecule 0.752884
SPATC1 spermatogenesis and centriole associated 1 0.751645
CXCL13 chemokine (C-X-C motif) ligand 13 0.740915
ALPL alkaline phosphatase, liver/bone/kidney 0.740915
CD79A CD79a molecule, immunoglobulin-associated alpha 0.738442
CD40 CD40 molecule, TNF receptor superfamily member 5 0.738442
IGHV3-9 immunoglobulin heavy variable 3-9 0.73803
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C 0.70968
AKAP17A A kinase (PRKA) anchor protein 17A 0.706812
PGLYRP1 peptidoglycan recognition protein 1 0.706402
ALPPL2 alkaline phosphatase, placental-like 2 0.705583
RCC1 regulator of chromosome condensation 1 0.700262
RPA3 replication protein A3, 14kDa 0.699853
GPRIN1 G protein regulated inducer of neurite outgrowth 1 0.699444
MALT1 MALT1 paracaspase 0.699444
PTPRC protein tyrosine phosphatase, receptor type, C 0.699035
CD1C CD1c molecule 0.696172
DRGX dorsal root ganglia homeobox 0.696172
INS insulin 0.689226
CCND3 cyclin D3 0.683511
CD37 CD37 molecule 0.665182
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.660304
HPGDS hematopoietic prostaglandin D synthase 0.658678
PAX5 paired box 5 0.658272
RB1 retinoblastoma 1 0.638404
CYTH4 cytohesin 4 0.636785
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.635167
IQSEC1 IQ motif and Sec7 domain 1 0.629101
PLXNA1 plexin A1 0.629101
RPL18 ribosomal protein L18 0.625061
CAT catalase 0.623043
TUBD1 tubulin, delta 1 0.61941
BMI1 BMI1 proto-oncogene, polycomb ring finger 0.617796
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.616183
HSPA4 heat shock 70kDa protein 4 0.604099
SOD2 superoxide dismutase 2, mitochondrial 0.602892
RING1 ring finger protein 1 0.600077
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.598469
ACHE acetylcholinesterase (Yt blood group) 0.594853
DLX1 distal-less homeobox 1 0.576415
PKLR pyruvate kinase, liver and RBC 0.572418
FCRL1 Fc receptor-like 1 0.567626
CDH7 cadherin 7, type 2 0.567626
CD9 CD9 molecule 0.567227
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase 0.566828
CD68 CD68 molecule 0.562042
CD27 CD27 molecule 0.561245
RPL10 ribosomal protein L10 0.559652
PAXBP1 PAX3 and PAX7 binding protein 1 0.559254
CHAT choline O-acetyltransferase 0.558856
NTN1 netrin 1 0.557661
IGKC immunoglobulin kappa constant 0.556865
CDH8 cadherin 8, type 2 0.556467
DNAH8 dynein, axonemal, heavy chain 8 0.551695
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.549312
ZNF503 zinc finger protein 503 0.548914
NGFR nerve growth factor receptor 0.546533
CDH20 cadherin 20, type 2 0.546136
IGLV3-19 immunoglobulin lambda variable 3-19 0.543756
PYGB phosphorylase, glycogen; brain 0.538604
PYGL phosphorylase, glycogen, liver 0.537416
DSPP dentin sialophosphoprotein 0.535438
LBX1 ladybird homeobox 1 0.535042
CDH19 cadherin 19, type 2 0.53267
SAP18 Sin3A-associated protein, 18kDa 0.532274
PYGM phosphorylase, glycogen, muscle 0.532274
POU3F3 POU class 3 homeobox 3 0.530298
GPSM2 G-protein signaling modulator 2 0.528323
APCS amyloid P component, serum 0.527139
DRAXIN dorsal inhibitory axon guidance protein 0.526744
PKM pyruvate kinase, muscle 0.522011
THEMIS thymocyte selection associated 0.521223
SOX4 SRY (sex determining region Y)-box 4 0.520435
ATM ATM serine/threonine kinase 0.518465
STMN1 stathmin 1 0.516891
MFAP2 microfibrillar-associated protein 2 0.51453
LHX9 LIM homeobox 9 0.514136
ALK anaplastic lymphoma receptor tyrosine kinase 0.50471
ACPP acid phosphatase, prostate 0.503926
PRELID1 PRELI domain containing 1 0.503141
CDH12 cadherin 12, type 2 (N-cadherin 2) 0.50275
HOXA6 homeobox A6 0.499615
BCL3 B-cell CLL/lymphoma 3 0.498048
SELL selectin L 0.492182
MAX MYC associated factor X 0.490619
DLX5 distal-less homeobox 5 0.489447
IGHV3-21 immunoglobulin heavy variable 3-21 0.485545
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.484766
GBX1 gastrulation brain homeobox 1 0.482428
FCRLA Fc receptor-like A 0.476201
TYR tyrosinase 0.473869
NCDN neurochondrin 0.472704
IRF4 interferon regulatory factor 4 0.464561
SH3GLB1 SH3-domain GRB2-like endophilin B1 0.463013
B2M beta-2-microglobulin 0.455284
RNPS1 RNA binding protein S1, serine-rich domain 0.452198
PAX6 paired box 6 0.452198
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 0.452198
TPM1 tropomyosin 1 (alpha) 0.450657
CCND2 cyclin D2 0.447961
OAT ornithine aminotransferase 0.440274
SHH sonic hedgehog 0.438739
SPAG4 sperm associated antigen 4 0.438356
PCNA proliferating cell nuclear antigen 0.437972
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.437205
LHX1 LIM homeobox 1 0.436055
CDK4 cyclin-dependent kinase 4 0.434523
LRMP lymphoid-restricted membrane protein 0.43146
CDH9 cadherin 9, type 2 (T1-cadherin) 0.429547
PIGB phosphatidylinositol glycan anchor biosynthesis, class B 0.429547
PNMA6A paraneoplastic Ma antigen family member 6A 0.427254
CD1B CD1b molecule 0.426872
ICAM2 intercellular adhesion molecule 2 0.42649
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 0.420004
ELN elastin 0.419242
A1BG alpha-1-B glycoprotein 0.417718
VCX variable charge, X-linked 0.416576
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.416576
ADSL adenylosuccinate lyase 0.415434
PAX2 paired box 2 0.414673
VCX2 variable charge, X-linked 2 0.412011
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.411251
RPTOR regulatory associated protein of MTOR, complex 1 0.407073
PVALB parvalbumin 0.406315
FTL ferritin, light polypeptide 0.405555
DSP desmoplakin 0.404797
VCX3B variable charge, X-linked 3B 0.402523
ACIN1 apoptotic chromatin condensation inducer 1 0.402144
NGF nerve growth factor (beta polypeptide) 0.401765
SYK spleen tyrosine kinase 0.398735
FTH1 ferritin, heavy polypeptide 1 0.398357
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.394953
UBQLN2 ubiquilin 2 0.393442
AMER1 APC membrane recruitment protein 1 0.393064
VCX3A variable charge, X-linked 3A 0.390799
TDP2 tyrosyl-DNA phosphodiesterase 2 0.387027
ICAM1 intercellular adhesion molecule 1 0.38439
TFDP1 transcription factor Dp-1 0.380251
GSTA3 glutathione S-transferase alpha 3 0.377621
CD24 CD24 molecule 0.377621
HOXA2 homeobox A2 0.377245
PDCD2 programmed cell death 2 0.377245
MNX1 motor neuron and pancreas homeobox 1 0.376119
GSTA4 glutathione S-transferase alpha 4 0.375743
GSTA2 glutathione S-transferase alpha 2 0.375743
PIM2 Pim-2 proto-oncogene, serine/threonine kinase 0.374243
TUBA1A tubulin, alpha 1a 0.374243
GSTA1 glutathione S-transferase alpha 1 0.371619
EBF1 early B-cell factor 1 0.371245
LCK LCK proto-oncogene, Src family tyrosine kinase 0.369747
BLNK B-cell linker 0.368998
CDKN2A cyclin-dependent kinase inhibitor 2A 0.367129
CNOT8 CCR4-NOT transcription complex, subunit 8 0.366754
GJB4 gap junction protein, beta 4, 30.3kDa 0.366007
FSCN3 fascin actin-bundling protein 3, testicular 0.364886
LZTS1 leucine zipper, putative tumor suppressor 1 0.35557
FOXB1 forkhead box B1 0.354455
HDAC10 histone deacetylase 10 0.353712
NKX2-1 NK2 homeobox 1 0.35334
FSCN2 fascin actin-bundling protein 2, retinal 0.352598
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.352598
TXN thioredoxin 0.350743
TYRL tyrosinase-like (pseudogene) 0.346298
AMELY amelogenin, Y-linked 0.344079
STPG1 sperm-tail PG-rich repeat containing 1 0.341126
TFRC transferrin receptor 0.340388
CD70 CD70 molecule 0.340388
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 0.340019
PCDH8 protocadherin 8 0.339282
SEPT1 septin 1 0.339282
CPVL carboxypeptidase, vitellogenic-like 0.336704
CYLD cylindromatosis (turban tumor syndrome) 0.335233
AMELX amelogenin, X-linked 0.335233
RYBP RING1 and YY1 binding protein 0.334498
RICTOR RPTOR independent companion of MTOR, complex 2 0.331927
OLIG3 oligodendrocyte transcription factor 3 0.329727
FKTN fukutin 0.328628
GBX2 gastrulation brain homeobox 2 0.328628
BAX BCL2-associated X protein 0.326067
LHX2 LIM homeobox 2 0.325701
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 0.324239
CDC14A cell division cycle 14A 0.324239
CP ceruloplasmin (ferroxidase) 0.322779
TH tyrosine hydroxylase 0.322779
GPX1 glutathione peroxidase 1 0.32205
CDA cytidine deaminase 0.320956
FCRL3 Fc receptor-like 3 0.319134
MARK1 MAP/microtubule affinity-regulating kinase 1 0.318042
PCDH7 protocadherin 7 0.317679
PCDH9 protocadherin 9 0.315861
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 0.315861
TMC1 transmembrane channel-like 1 0.314046
ARF4 ADP-ribosylation factor 4 0.312595
HOXD8 homeobox D8 0.312232
UBP1 upstream binding protein 1 (LBP-1a) 0.31187
RBP1 retinol binding protein 1, cellular 0.311145
NT5E 5'-nucleotidase, ecto (CD73) 0.310421
VCAM1 vascular cell adhesion molecule 1 0.310421
PFKM phosphofructokinase, muscle 0.310059
GFAP glial fibrillary acidic protein 0.308612
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 0.307889
FBF1 Fas (TNFRSF6) binding factor 1 0.307528
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.307528
CCL14 chemokine (C-C motif) ligand 14 0.306083
CD40LG CD40 ligand 0.305001
RNF2 ring finger protein 2 0.30464
HOXD1 homeobox D1 0.30464
MECOM MDS1 and EVI1 complex locus 0.303198
SIGLEC10 sialic acid binding Ig-like lectin 10 0.301398
CCNK cyclin K 0.300679
SERPINA9 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9 0.297447
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain 0.29673
REL v-rel avian reticuloendotheliosis viral oncogene homolog 0.294939
FN1 fibronectin 1 0.294581
BIRC3 baculoviral IAP repeat containing 3 0.294223
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 0.294223
NPS neuropeptide S 0.292793
KLF10 Kruppel-like factor 10 0.292436
CD52 CD52 molecule 0.292436
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain 0.291722
IGLV7-43 immunoglobulin lambda variable 7-43 0.291365
MSC musculin 0.289939
NKX6-1 NK6 homeobox 1 0.28887
PYY peptide YY 0.286381
POLM polymerase (DNA directed), mu 0.285671
POU2F2 POU class 2 homeobox 2 0.284962
MLF1 myeloid leukemia factor 1 0.284253
MFAP5 microfibrillar associated protein 5 0.283899
LIF leukemia inhibitory factor 0.279659
ARF1 ADP-ribosylation factor 1 0.278603
LHX5 LIM homeobox 5 0.278603
IGHMBP2 immunoglobulin mu binding protein 2 0.278603
PIGT phosphatidylinositol glycan anchor biosynthesis, class T 0.277549
SKP1 S-phase kinase-associated protein 1 0.277197
PGM2 phosphoglucomutase 2 0.275444
MPEG1 macrophage expressed 1 0.274394
DAP death-associated protein 0.273346
INSRR insulin receptor-related receptor 0.272649
CD72 CD72 molecule 0.270561
DBX1 developing brain homeobox 1 0.268828
BTK Bruton agammaglobulinemia tyrosine kinase 0.268482
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.266757
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.266413
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.265381
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 0.264011
GSX1 GS homeobox 1 0.262304
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like 0.261624
STRBP spermatid perinuclear RNA binding protein 0.259254
NEUROD6 neuronal differentiation 6 0.257237
SOX13 SRY (sex determining region Y)-box 13 0.255567
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 0.255567
CD69 CD69 molecule 0.25457
FAIM2 Fas apoptotic inhibitory molecule 2 0.253578
MGP matrix Gla protein 0.251934
ABRA actin binding Rho activating protein 0.250627
IL4I1 interleukin 4 induced 1 0.249437
ING3 inhibitor of growth family, member 3 0.249329
IL1A interleukin 1, alpha 0.249006
CDT1 chromatin licensing and DNA replication factor 1 0.24804
FEZF1 FEZ family zinc finger 1 0.247719
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha 0.24676
LRRC4C leucine rich repeat containing 4C 0.24676
ODF1 outer dense fiber of sperm tails 1 0.244232
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2 0.243918
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 0.241746
CD44 CD44 molecule (Indian blood group) 0.241438
KRT15 keratin 15, type I 0.239913
SELM selenoprotein M 0.239007
RGN regucalcin 0.238406
NRCAM neuronal cell adhesion molecule 0.23781
ACTB actin, beta 0.237513
INTU inturned planar cell polarity protein 0.237216
IGH immunoglobulin heavy locus 0.236921
NCAN neurocan 0.236332
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 0.23604
LMO2 LIM domain only 2 (rhombotin-like 1) 0.235457
CHIT1 chitinase 1 (chitotriosidase) 0.231482
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4 0.229299
GJB3 gap junction protein, beta 3, 31kDa 0.22684
CSF3 colony stimulating factor 3 (granulocyte) 0.226155
NODAL nodal growth differentiation factor 0.225144
GCSAM germinal center-associated, signaling and motility 0.225144
FGR FGR proto-oncogene, Src family tyrosine kinase 0.224893
ASCL1 achaete-scute family bHLH transcription factor 1 0.224398
ACTG1 actin gamma 1 0.224398
AATF apoptosis antagonizing transcription factor 0.222858
KIRREL2 kin of IRRE like 2 (Drosophila) 0.22246
VIL1 villin 1 0.221521
MAP2 microtubule-associated protein 2 0.220378
RXRG retinoid X receptor, gamma 0.219264
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.219264
MAP1A microtubule-associated protein 1A 0.217346
CDK20 cyclin-dependent kinase 20 0.216933
MRO maestro 0.216528
TECTA tectorin alpha 0.215928
CD34 CD34 molecule 0.215341
FGF19 fibroblast growth factor 19 0.214576
CDK6 cyclin-dependent kinase 6 0.214388
KCNIP4 Kv channel interacting protein 4 0.214388
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.214202
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.213833
ELAVL1 ELAV like RNA binding protein 1 0.200773
PAX3 paired box 3 0.198796
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 0.19534
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.194487
TTN titin 0.194153
CSN1S1 casein alpha s1 0.191785
CTSS cathepsin S 0.190994
GSR glutathione reductase 0.190708
PTPRD protein tyrosine phosphatase, receptor type, D 0.190323
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.190245
CS citrate synthase 0.188257
CTSD cathepsin D 0.18732
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.186448
TNNT2 troponin T type 2 (cardiac) 0.185899
GDNF glial cell derived neurotrophic factor 0.183524
FLT1 fms-related tyrosine kinase 1 0.182491
GPX5 glutathione peroxidase 5 0.179917
GPX4 glutathione peroxidase 4 0.179601