| Dataset | GeneRIF Biological Term Annotations |
| Category | structural or functional annotations |
| Type | biological term |
| Description | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase|The protein encoded by this gene is a serine/threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF-kappa-B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N-terminus and phospho-kinase activity conferred by a kinase domain in its C-terminus. [provided by RefSeq, Mar 2012] (NCBI Entrez Gene Database, 4214) |
| Similar Terms | |
| Downloads & Tools |
7 genes co-occuring with the biological term map3k1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
