| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
198 genes differentially expressed following the maprotiline-1621 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAR | adenosine deaminase, RNA-specific |
| AQR | aquarius intron-binding spliceosomal factor |
| ARF3 | ADP-ribosylation factor 3 |
| ARG1 | arginase 1 |
| ARL4A | ADP-ribosylation factor-like 4A |
| ATG10 | autophagy related 10 |
| ATG13 | autophagy related 13 |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) |
| CAP2 | CAP, adenylate cyclase-associated protein, 2 (yeast) |
| CAST | calpastatin |
| CCDC64 | coiled-coil domain containing 64 |
| CD300A | CD300a molecule |
| CEP85 | centrosomal protein 85kDa |
| CHPF2 | chondroitin polymerizing factor 2 |
| CLCN3 | chloride channel, voltage-sensitive 3 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CRY2 | cryptochrome circadian clock 2 |
| CTH | cystathionine gamma-lyase |
| CUL4B | cullin 4B |
| CYLD | cylindromatosis (turban tumor syndrome) |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DALRD3 | DALR anticodon binding domain containing 3 |
| DCTN4 | dynactin 4 (p62) |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DOK3 | docking protein 3 |
| DYRK4 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 |
| EGR3 | early growth response 3 |
| ELMO2 | engulfment and cell motility 2 |
| FBXO9 | F-box protein 9 |
| FLI1 | Fli-1 proto-oncogene, ETS transcription factor |
| GAB2 | GRB2-associated binding protein 2 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 |
| GIMAP5 | GTPase, IMAP family member 5 |
| GOLM1 | golgi membrane protein 1 |
| GOLPH3L | golgi phosphoprotein 3-like |
| GP1BA | glycoprotein Ib (platelet), alpha polypeptide |
| GPNMB | glycoprotein (transmembrane) nmb |
| GPSM3 | G-protein signaling modulator 3 |
| H3F3B | H3 histone, family 3B (H3.3B) |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) |
| INTS9 | integrator complex subunit 9 |
| ITSN1 | intersectin 1 (SH3 domain protein) |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LHFP | lipoma HMGIC fusion partner |
| LPAR1 | lysophosphatidic acid receptor 1 |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| LUC7L | LUC7-like (S. cerevisiae) |
| MAP2K6 | mitogen-activated protein kinase kinase 6 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| METTL8 | methyltransferase like 8 |
| MLH3 | mutL homolog 3 |
| MPPE1 | metallophosphoesterase 1 |
| MST1 | macrophage stimulating 1 |
| MTRR | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase |
| NBR1 | neighbor of BRCA1 gene 1 |
| NCOA3 | nuclear receptor coactivator 3 |
| NDE1 | nudE neurodevelopment protein 1 |
| NPAT | nuclear protein, ataxia-telangiectasia locus |
| PCGF1 | polycomb group ring finger 1 |
| PDCL | phosducin-like |
| PGC | progastricsin (pepsinogen C) |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) |
| PRKAB1 | protein kinase, AMP-activated, beta 1 non-catalytic subunit |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 |
| RAB6B | RAB6B, member RAS oncogene family |
| RASSF4 | Ras association (RalGDS/AF-6) domain family member 4 |
| RFX5 | regulatory factor X, 5 (influences HLA class II expression) |
| RHOT2 | ras homolog family member T2 |
| RIN3 | Ras and Rab interactor 3 |
| RNF2 | ring finger protein 2 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SETD4 | SET domain containing 4 |
| SIRAL2 | SIR2 antiphage like 2 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 |
| SLC45A2 | solute carrier family 45, member 2 |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SPTLC1 | serine palmitoyltransferase, long chain base subunit 1 |
| SRR | serine racemase |
| STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 |
| STK4 | serine/threonine kinase 4 |
| TBC1D29 | TBC1 domain family, member 29 |
| TMEM127 | transmembrane protein 127 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TRAM2 | translocation associated membrane protein 2 |
| VILL | villin-like |
| ZCCHC14 | zinc finger, CCHC domain containing 14 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF134 | zinc finger protein 134 |
| ZNF408 | zinc finger protein 408 |
| ZNF510 | zinc finger protein 510 |
| ZNF518A | zinc finger protein 518A |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ARMC7 | armadillo repeat containing 7 |
| ATG2A | autophagy related 2A |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BRD9 | bromodomain containing 9 |
| C19ORF24 | chromosome 19 open reading frame 24 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CAPN15 | calpain 15 |
| CD69 | CD69 molecule |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CIDEC | cell death-inducing DFFA-like effector c |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 |
| CSK | c-src tyrosine kinase |
| CTSC | cathepsin C |
| DIXDC1 | DIX domain containing 1 |
| DOLK | dolichol kinase |
| DPP3 | dipeptidyl-peptidase 3 |
| EDEM2 | ER degradation enhancer, mannosidase alpha-like 2 |
| EGR2 | early growth response 2 |
| ERF | Ets2 repressor factor |
| FBXL14 | F-box and leucine-rich repeat protein 14 |
| FBXO5 | F-box protein 5 |
| FCHO1 | FCH domain only 1 |
| FMO4 | flavin containing monooxygenase 4 |
| FTO | fat mass and obesity associated |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GOLGA3 | golgin A3 |
| GRPR | gastrin-releasing peptide receptor |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HOOK2 | hook microtubule-tethering protein 2 |
| IFNA17 | interferon, alpha 17 |
| INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa |
| JMJD4 | jumonji domain containing 4 |
| LIN7C | lin-7 homolog C (C. elegans) |
| LOC642236 | FSHD region gene 1 pseudogene |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) |
| MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MMP2 | matrix metallopeptidase 2 |
| MOSPD3 | motile sperm domain containing 3 |
| MPP6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
| MPST | mercaptopyruvate sulfurtransferase |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit |
| NABP2 | nucleic acid binding protein 2 |
| NAPG | N-ethylmaleimide-sensitive factor attachment protein, gamma |
| NHLRC2 | NHL repeat containing 2 |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| OCEL1 | occludin/ELL domain containing 1 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| PANX1 | pannexin 1 |
| PDCD10 | programmed cell death 10 |
| PDZD8 | PDZ domain containing 8 |
| PEX7 | peroxisomal biogenesis factor 7 |
| PMM1 | phosphomannomutase 1 |
| PMM2 | phosphomannomutase 2 |
| PNOC | prepronociceptin |
| PODNL1 | podocan-like 1 |
| POLE | polymerase (DNA directed), epsilon, catalytic subunit |
| PSTPIP1 | proline-serine-threonine phosphatase interacting protein 1 |
| PTBP2 | polypyrimidine tract binding protein 2 |
| RNF167 | ring finger protein 167 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPP38 | ribonuclease P/MRP 38kDa subunit |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| RRP1 | ribosomal RNA processing 1 |
| SASH3 | SAM and SH3 domain containing 3 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SCRIB | scribbled planar cell polarity protein |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| TAC3 | tachykinin 3 |
| TFCP2L1 | transcription factor CP2-like 1 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) |
| TMEM14A | transmembrane protein 14A |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TSPYL4 | TSPY-like 4 |
| TTC13 | tetratricopeptide repeat domain 13 |
| TUBB3 | tubulin, beta 3 class III |
| TWIST1 | twist family bHLH transcription factor 1 |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 |
| VASP | vasodilator-stimulated phosphoprotein |
| WFDC2 | WAP four-disulfide core domain 2 |
| YTHDF2 | YTH N(6)-methyladenosine RNA binding protein 2 |
| ZBTB24 | zinc finger and BTB domain containing 24 |
| ZNF443 | zinc finger protein 443 |
| ZNF562 | zinc finger protein 562 |
