| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the maprotiline-3236 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAA2 | acetyl-CoA acyltransferase 2 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADH1A | alcohol dehydrogenase 1A (class I), alpha polypeptide |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| AHNAK2 | AHNAK nucleoprotein 2 |
| AIF1 | allograft inflammatory factor 1 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 |
| ATP1A3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| CA4 | carbonic anhydrase IV |
| CCPG1 | cell cycle progression 1 |
| CDHR2 | cadherin-related family member 2 |
| CDK13 | cyclin-dependent kinase 13 |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CEL | carboxyl ester lipase |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| CTSF | cathepsin F |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DENND5B | DENN/MADD domain containing 5B |
| DNM3 | dynamin 3 |
| DST | dystonin |
| DUSP4 | dual specificity phosphatase 4 |
| EDNRA | endothelin receptor type A |
| EFNB3 | ephrin-B3 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FAM105A | family with sequence similarity 105, member A |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| GSK3A | glycogen synthase kinase 3 alpha |
| HBS1L | HBS1-like translational GTPase |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HOXA4 | homeobox A4 |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| INSIG1 | insulin induced gene 1 |
| IQCG | IQ motif containing G |
| LDLR | low density lipoprotein receptor |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LPIN1 | lipin 1 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MAN2A2 | mannosidase, alpha, class 2A, member 2 |
| MTAP | methylthioadenosine phosphorylase |
| MTSS1 | metastasis suppressor 1 |
| NDRG2 | NDRG family member 2 |
| NEU3 | sialidase 3 (membrane sialidase) |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NPR1 | natriuretic peptide receptor 1 |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCBP3 | poly(rC) binding protein 3 |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PLA2G3 | phospholipase A2, group III |
| POU5F1B | POU class 5 homeobox 1B |
| PSD3 | pleckstrin and Sec7 domain containing 3 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RBFA | ribosome binding factor A (putative) |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RS1 | retinoschisin 1 |
| RUNX1 | runt-related transcription factor 1 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 |
| SHOX2 | short stature homeobox 2 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 |
| SIRT5 | sirtuin 5 |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SMIM14 | small integral membrane protein 14 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPARCL1 | SPARC-like 1 (hevin) |
| SQLE | squalene epoxidase |
| SRF | serum response factor (c-fos serum response element-binding transcription factor) |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
| STIM1 | stromal interaction molecule 1 |
| TAGLN3 | transgelin 3 |
| TBC1D2 | TBC1 domain family, member 2 |
| TEX14 | testis expressed 14 |
| TGFB2 | transforming growth factor, beta 2 |
| TGFBR1 | transforming growth factor, beta receptor 1 |
| TGM2 | transglutaminase 2 |
| TLK1 | tousled-like kinase 1 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TM6SF2 | transmembrane 6 superfamily member 2 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TPM2 | tropomyosin 2 (beta) |
| TRPM8 | transient receptor potential cation channel, subfamily M, member 8 |
| VWA5A | von Willebrand factor A domain containing 5A |
| ZXDB | zinc finger, X-linked, duplicated B |
| Symbol | Name |
|---|---|
| AIPL1 | aryl hydrocarbon receptor interacting protein-like 1 |
| ALOX15 | arachidonate 15-lipoxygenase |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BMP4 | bone morphogenetic protein 4 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
| CD82 | CD82 molecule |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDK5 | cyclin-dependent kinase 5 |
| CDON | cell adhesion associated, oncogene regulated |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CFAP69 | cilia and flagella associated protein 69 |
| CGA | glycoprotein hormones, alpha polypeptide |
| CORO7 | coronin 7 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CRYGC | crystallin, gamma C |
| CSF1R | colony stimulating factor 1 receptor |
| CSTA | cystatin A (stefin A) |
| CUEDC1 | CUE domain containing 1 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DAGLA | diacylglycerol lipase, alpha |
| DEAF1 | DEAF1 transcription factor |
| DOK2 | docking protein 2, 56kDa |
| DPYS | dihydropyrimidinase |
| DYSF | dysferlin |
| EXO5 | exonuclease 5 |
| FAAH | fatty acid amide hydrolase |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FBXO31 | F-box protein 31 |
| FGF6 | fibroblast growth factor 6 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FOSL1 | FOS-like antigen 1 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPATCH2L | G patch domain containing 2-like |
| HAMP | hepcidin antimicrobial peptide |
| HIST1H2AL | histone cluster 1, H2al |
| HIST1H2BC | histone cluster 1, H2bc |
| IL15RA | interleukin 15 receptor, alpha |
| IL4R | interleukin 4 receptor |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KCNA6 | potassium channel, voltage gated shaker related subfamily A, member 6 |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 |
| KLHL26 | kelch-like family member 26 |
| LDHB | lactate dehydrogenase B |
| LIN7B | lin-7 homolog B (C. elegans) |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LYZ | lysozyme |
| MSI1 | musashi RNA-binding protein 1 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NLGN1 | neuroligin 1 |
| NLRX1 | NLR family member X1 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| OLFML3 | olfactomedin-like 3 |
| PC | pyruvate carboxylase |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PDE12 | phosphodiesterase 12 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PODNL1 | podocan-like 1 |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RAPSN | receptor-associated protein of the synapse |
| RIN2 | Ras and Rab interactor 2 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCG2 | secretogranin II |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| STAB2 | stabilin 2 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TCTN1 | tectonic family member 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM120B | transmembrane protein 120B |
| TRIM25 | tripartite motif containing 25 |
| TUBA3C | tubulin, alpha 3c |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| TWF2 | twinfilin actin binding protein 2 |
| UBTD1 | ubiquitin domain containing 1 |
| ULBP2 | UL16 binding protein 2 |
| ZIC3 | Zic family member 3 |
| ZNF16 | zinc finger protein 16 |
| ZNF205 | zinc finger protein 205 |
| ZNF34 | zinc finger protein 34 |
