| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the maprotiline-5022 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit |
| AQP3 | aquaporin 3 (Gill blood group) |
| ASIC4 | acid sensing (proton gated) ion channel family member 4 |
| ATF3 | activating transcription factor 3 |
| ATXN1 | ataxin 1 |
| BAX | BCL2-associated X protein |
| BBS9 | Bardet-Biedl syndrome 9 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| CCNG2 | cyclin G2 |
| CDK13 | cyclin-dependent kinase 13 |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CXORF21 | chromosome X open reading frame 21 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP4 | dual specificity phosphatase 4 |
| ECE1 | endothelin converting enzyme 1 |
| EGR1 | early growth response 1 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B |
| ETV5 | ets variant 5 |
| FAM117A | family with sequence similarity 117, member A |
| FLJ42627 | uncharacterized LOC645644 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GLRX3 | glutaredoxin 3 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST1H4E | histone cluster 1, H4e |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMOX1 | heme oxygenase 1 |
| HSD17B7 | hydroxysteroid (17-beta) dehydrogenase 7 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| ICAM1 | intercellular adhesion molecule 1 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IGSF6 | immunoglobulin superfamily, member 6 |
| IL23A | interleukin 23, alpha subunit p19 |
| ING1 | inhibitor of growth family, member 1 |
| INSIG1 | insulin induced gene 1 |
| IRS2 | insulin receptor substrate 2 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| KLF2 | Kruppel-like factor 2 |
| KLF6 | Kruppel-like factor 6 |
| KLHL24 | kelch-like family member 24 |
| LDLR | low density lipoprotein receptor |
| LIF | leukemia inhibitory factor |
| LPIN1 | lipin 1 |
| LPXN | leupaxin |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MSMO1 | methylsterol monooxygenase 1 |
| MT1F | metallothionein 1F |
| MVD | mevalonate (diphospho) decarboxylase |
| MVK | mevalonate kinase |
| MYBPC3 | myosin binding protein C, cardiac |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NF1 | neurofibromin 1 |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| POLM | polymerase (DNA directed), mu |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RUNX1 | runt-related transcription factor 1 |
| S100A13 | S100 calcium binding protein A13 |
| S100A8 | S100 calcium binding protein A8 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SMC1A | structural maintenance of chromosomes 1A |
| SMG7 | SMG7 nonsense mediated mRNA decay factor |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SQLE | squalene epoxidase |
| TLR2 | toll-like receptor 2 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 |
| TRIB3 | tribbles pseudokinase 3 |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| VASH2 | vasohibin 2 |
| Symbol | Name |
|---|---|
| AGMAT | agmatine ureohydrolase (agmatinase) |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALPK1 | alpha-kinase 1 |
| AMT | aminomethyltransferase |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CBX8 | chromobox homolog 8 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCDC121 | coiled-coil domain containing 121 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CD83 | CD83 molecule |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CISH | cytokine inducible SH2-containing protein |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CLDN9 | claudin 9 |
| CSF1R | colony stimulating factor 1 receptor |
| DBR1 | debranching RNA lariats 1 |
| DUSP2 | dual specificity phosphatase 2 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| FAM50B | family with sequence similarity 50, member B |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FOXN2 | forkhead box N2 |
| FRMD1 | FERM domain containing 1 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GALK1 | galactokinase 1 |
| GK3P | glycerol kinase 3 pseudogene |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| INO80D | INO80 complex subunit D |
| KDM8 | lysine (K)-specific demethylase 8 |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase |
| LIN7A | lin-7 homolog A (C. elegans) |
| LOC390998 | ribosomal protein L10 pseudogene |
| LOC729164 | hCG1732469 |
| MCOLN1 | mucolipin 1 |
| MSI1 | musashi RNA-binding protein 1 |
| MSX1 | msh homeobox 1 |
| MYOZ3 | myozenin 3 |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NME5 | NME/NM23 family member 5 |
| NPR3 | natriuretic peptide receptor 3 |
| NPY5R | neuropeptide Y receptor Y5 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PER3 | period circadian clock 3 |
| PGBD5 | piggyBac transposable element derived 5 |
| PLCD1 | phospholipase C, delta 1 |
| PRF1 | perforin 1 (pore forming protein) |
| PRKCE | protein kinase C, epsilon |
| PTCD1 | pentatricopeptide repeat domain 1 |
| PVRL3 | poliovirus receptor-related 3 |
| RAB3A | RAB3A, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF25 | ring finger protein 25 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPL10L | ribosomal protein L10-like |
| RWDD3 | RWD domain containing 3 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SLC10A3 | solute carrier family 10, member 3 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SLN | sarcolipin |
| SOX3 | SRY (sex determining region Y)-box 3 |
| SPAG4 | sperm associated antigen 4 |
| STOML1 | stomatin (EPB72)-like 1 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| SYCP2 | synaptonemal complex protein 2 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TBC1D19 | TBC1 domain family, member 19 |
| TCHH | trichohyalin |
| TCP10 | t-complex 10 |
| TEX40 | testis expressed 40 |
| TGFBR3 | transforming growth factor, beta receptor III |
| TMC5 | transmembrane channel-like 5 |
| TMEM180 | transmembrane protein 180 |
| TRIM45 | tripartite motif containing 45 |
| TSGA10 | testis specific, 10 |
| TUBA4B | tubulin, alpha 4b |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| WDR25 | WD repeat domain 25 |
| WDR3 | WD repeat domain 3 |
| XK | X-linked Kx blood group |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZNF227 | zinc finger protein 227 |
| ZNF573 | zinc finger protein 573 |
| ZNF639 | zinc finger protein 639 |
| ZNF862 | zinc finger protein 862 |
