mapt Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description microtubule-associated protein tau|This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4137)
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Genes

17 genes co-occuring with the biological term mapt in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
C9ORF72 chromosome 9 open reading frame 72
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
GRN granulin
GSK3B glycogen synthase kinase 3 beta
LRRK2 leucine-rich repeat kinase 2
MAPT microtubule-associated protein tau
MIR34C microRNA 34c
MYC v-myc avian myelocytomatosis viral oncogene homolog
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PSEN1 presenilin 1
PSEN2 presenilin 2
SNAP25 synaptosomal-associated protein, 25kDa
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SYP synaptophysin
TARDBP TAR DNA binding protein