|Dataset||GO Biological Process Annotations|
|Category||structural or functional annotations|
|Description||The process in which a B cell in the spleen acquires the specialized features of a marginal zone B cell. Marginal zone B cells are localized in a distinct anatomical region of the spleen that represents the major antigen-filtering and scavenging area (by specialized macrophages resident there). It appears that they are preselected to express a BCR repertoire similar to B-1 B cells, biased toward bacterial cell wall constituents and senescent self-components (such as oxidized LDL). (Gene Ontology, GO_0002315)|
|Downloads & Tools|
2 genes participating in the marginal zone b cell differentiation biological process from the curated GO Biological Process Annotations dataset.