maximal Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

191 genes co-occuring with the biological term maximal in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACE angiotensin I converting enzyme
ACO1 aconitase 1, soluble
ACSS2 acyl-CoA synthetase short-chain family member 2
ACTB actin, beta
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRB3 adrenoceptor beta 3
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AHSG alpha-2-HS-glycoprotein
AKT1 v-akt murine thymoma viral oncogene homolog 1
APOA1 apolipoprotein A-I
APOE apolipoprotein E
ARRB1 arrestin, beta 1
ATF1 activating transcription factor 1
ATG14 autophagy related 14
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP4B ATPase, H+/K+ exchanging, beta polypeptide
AXIN2 axin 2
B2M beta-2-microglobulin
BECN1 beclin 1, autophagy related
BID BH3 interacting domain death agonist
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CAMP cathelicidin antimicrobial peptide
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCL20 chemokine (C-C motif) ligand 20
CCNB1 cyclin B1
CD28 CD28 molecule
CD34 CD34 molecule
CD44 CD44 molecule (Indian blood group)
CDC20 cell division cycle 20
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDK5 cyclin-dependent kinase 5
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CFL1 cofilin 1 (non-muscle)
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CGA glycoprotein hormones, alpha polypeptide
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal)
CISD1 CDGSH iron sulfur domain 1
COMT catechol-O-methyltransferase
COX4I2 cytochrome c oxidase subunit IV isoform 2 (lung)
CREB1 cAMP responsive element binding protein 1
CREB3 cAMP responsive element binding protein 3
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CXCL8 chemokine (C-X-C motif) ligand 8
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYTH1 cytohesin 1
DDB1 damage-specific DNA binding protein 1, 127kDa
DDT D-dopachrome tautomerase
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DNM1 dynamin 1
DNM3 dynamin 3
DRD4 dopamine receptor D4
EFNA1 ephrin-A1
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ELN elastin
EPAS1 endothelial PAS domain protein 1
F10 coagulation factor X
F2 coagulation factor II (thrombin)
FAS Fas cell surface death receptor
FBN2 fibrillin 2
FLT1 fms-related tyrosine kinase 1
FOXP3 forkhead box P3
FXN frataxin
GCSAM germinal center-associated, signaling and motility
GHRL ghrelin/obestatin prepropeptide
GLI1 GLI family zinc finger 1
GLRA1 glycine receptor, alpha 1
GP6 glycoprotein VI (platelet)
GUCA1A guanylate cyclase activator 1A (retina)
HCFC1 host cell factor C1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HIST1H1B histone cluster 1, H1b
HNF4A hepatocyte nuclear factor 4, alpha
IFIH1 interferon induced with helicase C domain 1
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IL10 interleukin 10
IL15 interleukin 15
IL6 interleukin 6
INS insulin
IRF3 interferon regulatory factor 3
IRS2 insulin receptor substrate 2
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KDR kinase insert domain receptor
KIF4A kinesin family member 4A
LAP3 leucine aminopeptidase 3
LEP leptin
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
MAOB monoamine oxidase B
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAVS mitochondrial antiviral signaling protein
MCL1 myeloid cell leukemia 1
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MMP1 matrix metallopeptidase 1
MMP26 matrix metallopeptidase 26
MYBPC3 myosin binding protein C, cardiac
MYH7 myosin, heavy chain 7, cardiac muscle, beta
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NPPB natriuretic peptide B
NPR2 natriuretic peptide receptor 2
NPY neuropeptide Y
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR1I3 nuclear receptor subfamily 1, group I, member 3
NR3C2 nuclear receptor subfamily 3, group C, member 2
NR5A1 nuclear receptor subfamily 5, group A, member 1
NR5A2 nuclear receptor subfamily 5, group A, member 2
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
PARP1 poly (ADP-ribose) polymerase 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLAUR plasminogen activator, urokinase receptor
PLN phospholamban
PON1 paraoxonase 1
PRKCA protein kinase C, alpha
PRODH proline dehydrogenase (oxidase) 1
PROM1 prominin 1
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH parathyroid hormone
PTK2 protein tyrosine kinase 2
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RET ret proto-oncogene
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RUNX3 runt-related transcription factor 3
RYR1 ryanodine receptor 1 (skeletal)
SAMHD1 SAM domain and HD domain 1
SCN5A sodium channel, voltage gated, type V alpha subunit
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SEPT7 septin 7
SEPW1 selenoprotein W, 1
SGK1 serum/glucocorticoid regulated kinase 1
SGK3 serum/glucocorticoid regulated kinase family, member 3
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC29A4 solute carrier family 29 (equilibrative nucleoside transporter), member 4
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SOD3 superoxide dismutase 3, extracellular
SP1 Sp1 transcription factor
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STK25 serine/threonine kinase 25
TFF1 trefoil factor 1
THBS1 thrombospondin 1
THPO thrombopoietin
TICAM1 toll-like receptor adaptor molecule 1
TIGAR TP53 induced glycolysis regulatory phosphatase
TIMP4 TIMP metallopeptidase inhibitor 4
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TNF tumor necrosis factor
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNNC1 troponin C type 1 (slow)
TNNI3 troponin I type 3 (cardiac)
TNNT2 troponin T type 2 (cardiac)
TP53 tumor protein p53
TPM1 tropomyosin 1 (alpha)
VASP vasodilator-stimulated phosphoprotein
VEGFA vascular endothelial growth factor A
VKORC1 vitamin K epoxide reductase complex, subunit 1
XYLT1 xylosyltransferase I
ZC3HAV1 zinc finger CCCH-type, antiviral 1