mbl2 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description mannose-binding lectin (protein C) 2, soluble|This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4153)
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Genes

20 genes co-occuring with the biological term mbl2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACE angiotensin I converting enzyme
APOE apolipoprotein E
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CHIT1 chitinase 1 (chitotriosidase)
DEFB1 defensin, beta 1
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
IL1RN interleukin 1 receptor antagonist
IL4 interleukin 4
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MASP2 mannan-binding lectin serine peptidase 2
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MBL2 mannose-binding lectin (protein C) 2, soluble
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
PDGFB platelet-derived growth factor beta polypeptide
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
TGFB1 transforming growth factor, beta 1
TLR4 toll-like receptor 4
VEGFA vascular endothelial growth factor A