mcm complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A hexameric protein complex required for the initiation and regulation of DNA replication. (Gene Ontology, GO_0042555)
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Genes

112 proteins co-occuring with the mcm complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
MCM7 minichromosome maintenance complex component 7 3.64801
MCM2 minichromosome maintenance complex component 2 3.28658
MCM6 minichromosome maintenance complex component 6 2.49945
MCM3 minichromosome maintenance complex component 3 2.40092
MCM4 minichromosome maintenance complex component 4 2.39105
MCM5 minichromosome maintenance complex component 5 2.20148
MUT methylmalonyl CoA mutase 2.10638
CDC6 cell division cycle 6 1.95653
CDT1 chromatin licensing and DNA replication factor 1 1.95232
GMNN geminin, DNA replication inhibitor 1.82457
CDC45 cell division cycle 45 1.58737
CDC7 cell division cycle 7 1.56389
MCM10 minichromosome maintenance complex component 10 1.5565
MCMBP minichromosome maintenance complex binding protein 1.54122
DBF4 DBF4 zinc finger 1.38073
MCM9 minichromosome maintenance complex component 9 1.31627
CDK2 cyclin-dependent kinase 2 1.20241
PRIM2 primase, DNA, polypeptide 2 (58kDa) 1.15723
KAT7 K(lysine) acetyltransferase 7 1.06094
PCNA proliferating cell nuclear antigen 0.980987
TOP2A topoisomerase (DNA) II alpha 170kDa 0.926074
MCM8 minichromosome maintenance complex component 8 0.925135
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.767715
MCM3AP minichromosome maintenance complex component 3 associated protein 0.758161
GINS4 GINS complex subunit 4 (Sld5 homolog) 0.701304
E2F5 E2F transcription factor 5, p130-binding 0.628613
ZNF143 zinc finger protein 143 0.620529
CDKN2A cyclin-dependent kinase inhibitor 2A 0.577999
MMS22L MMS22-like, DNA repair protein 0.572578
PRIM1 primase, DNA, polypeptide 1 (49kDa) 0.565923
MKI67 marker of proliferation Ki-67 0.557214
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 0.548122
TONSL tonsoku-like, DNA repair protein 0.539883
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 0.520206
EVI2B ecotropic viral integration site 2B 0.518165
TP53 tumor protein p53 0.51694
CCND1 cyclin D1 0.507163
POLD3 polymerase (DNA-directed), delta 3, accessory subunit 0.497015
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.486096
VSIG4 V-set and immunoglobulin domain containing 4 0.480855
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.472813
CHEK1 checkpoint kinase 1 0.468001
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 0.457208
MT1F metallothionein 1F 0.454019
AKAP8 A kinase (PRKA) anchor protein 8 0.440124
PLK1 polo-like kinase 1 0.433407
CKS1B CDC28 protein kinase regulatory subunit 1B 0.426711
RFC3 replication factor C (activator 1) 3, 38kDa 0.425924
RFC5 replication factor C (activator 1) 5, 36.5kDa 0.423567
RFC4 replication factor C (activator 1) 4, 37kDa 0.422389
CINP cyclin-dependent kinase 2 interacting protein 0.41886
DNAH8 dynein, axonemal, heavy chain 8 0.418468
RBMY1F RNA binding motif protein, Y-linked, family 1, member F 0.415728
CDK4 cyclin-dependent kinase 4 0.407919
ATRIP ATR interacting protein 0.405193
ATM ATM serine/threonine kinase 0.388909
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 0.385051
TIPIN TIMELESS interacting protein 0.380814
MT1X metallothionein 1X 0.368153
RFC2 replication factor C (activator 1) 2, 40kDa 0.365859
RBMY1J RNA binding motif protein, Y-linked, family 1, member J 0.363949
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 0.359752
JADE1 jade family PHD finger 1 0.355183
HNRNPL heterogeneous nuclear ribonucleoprotein L 0.341529
WDR83 WD repeat domain 83 0.338506
UBD ubiquitin D 0.332848
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) 0.330589
PRSS50 protease, serine, 50 0.316334
WDHD1 WD repeat and HMG-box DNA binding protein 1 0.310732
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.308122
H3F3B H3 histone, family 3B (H3.3B) 0.304771
H3F3A H3 histone, family 3A 0.304771
MRGBP MRG/MORF4L binding protein 0.301797
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 0.286614
TOP3A topoisomerase (DNA) III alpha 0.283663
CDK1 cyclin-dependent kinase 1 0.281821
TAGLN2 transgelin 2 0.27998
NCOA4 nuclear receptor coactivator 4 0.279612
RAD51 RAD51 recombinase 0.279061
RFC1 replication factor C (activator 1) 1, 145kDa 0.270068
ATR ATR serine/threonine kinase 0.266774
KLF15 Kruppel-like factor 15 0.266774
CCNB2 cyclin B2 0.266042
TIMELESS timeless circadian clock 0.265677
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.254017
CCNB1 cyclin B1 0.251114
SETD1B SET domain containing 1B 0.233459
DDAH2 dimethylarginine dimethylaminohydrolase 2 0.225622
THOC1 THO complex 1 0.214714
BTF3 basic transcription factor 3 0.212627
RBM3 RNA binding motif (RNP1, RRM) protein 3 0.211933
CAPRIN1 cell cycle associated protein 1 0.209169
IRS4 insulin receptor substrate 4 0.206082
RB1 retinoblastoma 1 0.19733
SNF8 SNF8, ESCRT-II complex subunit 0.196669
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.193719
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) 0.18796
PLK2 polo-like kinase 2 0.187333
S100A13 S100 calcium binding protein A13 0.184547
UBE2C ubiquitin-conjugating enzyme E2C 0.183025
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.179752
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24 0.178299
MYB v-myb avian myeloblastosis viral oncogene homolog 0.177724
HMGB2 high mobility group box 2 0.171937
MSH5 mutS homolog 5 0.169859
CDC25A cell division cycle 25A 0.168598
CCNE2 cyclin E2 0.168101
KLK3 kallikrein-related peptidase 3 0.166884
ADGRE5 adhesion G protein-coupled receptor E5 0.165932
ATAD5 ATPase family, AAA domain containing 5 0.16342
DCX doublecortin 0.1632
AURKA aurora kinase A 0.158129