| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the mebendazole-2300 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| ALDOB | aldolase B, fructose-bisphosphate |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| AREG | amphiregulin |
| ATF3 | activating transcription factor 3 |
| C17ORF59 | chromosome 17 open reading frame 59 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CALD1 | caldesmon 1 |
| CD28 | CD28 molecule |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CFHR4 | complement factor H-related 4 |
| CLDN1 | claudin 1 |
| CSN3 | casein kappa |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP2W1 | cytochrome P450, family 2, subfamily W, polypeptide 1 |
| DFNB31 | deafness, autosomal recessive 31 |
| DMP1 | dentin matrix acidic phosphoprotein 1 |
| DSC2 | desmocollin 2 |
| DUSP4 | dual specificity phosphatase 4 |
| EGR1 | early growth response 1 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| ETV5 | ets variant 5 |
| F5 | coagulation factor V (proaccelerin, labile factor) |
| FOSL1 | FOS-like antigen 1 |
| FRMD1 | FERM domain containing 1 |
| G0S2 | G0/G1 switch 2 |
| GMPR | guanosine monophosphate reductase |
| GRB10 | growth factor receptor-bound protein 10 |
| GREB1 | growth regulation by estrogen in breast cancer 1 |
| GSTA1 | glutathione S-transferase alpha 1 |
| HCG4 | HLA complex group 4 (non-protein coding) |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| HYAL4 | hyaluronoglucosaminidase 4 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| ICAM1 | intercellular adhesion molecule 1 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IL23A | interleukin 23, alpha subunit p19 |
| INHBE | inhibin, beta E |
| KLF6 | Kruppel-like factor 6 |
| KLK1 | kallikrein 1 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LAT2 | linker for activation of T cells family, member 2 |
| LENEP | lens epithelial protein |
| LIF | leukemia inhibitory factor |
| LOC157562 | uncharacterized LOC157562 |
| LPIN1 | lipin 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MALL | mal, T-cell differentiation protein-like |
| MMP11 | matrix metallopeptidase 11 |
| MSI1 | musashi RNA-binding protein 1 |
| MTSS1L | metastasis suppressor 1-like |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NME5 | NME/NM23 family member 5 |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PHOX2A | paired-like homeobox 2a |
| PHTF2 | putative homeodomain transcription factor 2 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PML | promyelocytic leukemia |
| PRKCA | protein kinase C, alpha |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RS1 | retinoschisin 1 |
| RSL1D1 | ribosomal L1 domain containing 1 |
| RUNX1 | runt-related transcription factor 1 |
| S100A13 | S100 calcium binding protein A13 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A |
| SERPINB13 | serpin peptidase inhibitor, clade B (ovalbumin), member 13 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC45A2 | solute carrier family 45, member 2 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SRCAP | Snf2-related CREBBP activator protein |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TAS2R10 | taste receptor, type 2, member 10 |
| TECPR2 | tectonin beta-propeller repeat containing 2 |
| TLR2 | toll-like receptor 2 |
| TM4SF5 | transmembrane 4 L six family member 5 |
| TRIM49 | tripartite motif containing 49 |
| ZBTB43 | zinc finger and BTB domain containing 43 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZNF76 | zinc finger protein 76 |
| ZYX | zyxin |
| Symbol | Name |
|---|---|
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BCLAF1 | BCL2-associated transcription factor 1 |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| C11ORF68 | chromosome 11 open reading frame 68 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CA2 | carbonic anhydrase II |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CCDC132 | coiled-coil domain containing 132 |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CRY2 | cryptochrome circadian clock 2 |
| DEAF1 | DEAF1 transcription factor |
| DENND4A | DENN/MADD domain containing 4A |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM114A2 | family with sequence similarity 114, member A2 |
| FKBP5 | FK506 binding protein 5 |
| FOXD1 | forkhead box D1 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GTPBP3 | GTP binding protein 3 (mitochondrial) |
| HIST1H2AI | histone cluster 1, H2ai |
| HOXC6 | homeobox C6 |
| HPN | hepsin |
| HSPA1L | heat shock 70kDa protein 1-like |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| IGSF1 | immunoglobulin superfamily, member 1 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KCNJ3 | potassium channel, inwardly rectifying subfamily J, member 3 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 |
| LAS1L | LAS1-like (S. cerevisiae) |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MAP9 | microtubule-associated protein 9 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MED15 | mediator complex subunit 15 |
| METTL16 | methyltransferase like 16 |
| MSANTD2 | Myb/SANT-like DNA-binding domain containing 2 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NPY5R | neuropeptide Y receptor Y5 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| NUPL2 | nucleoporin like 2 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PCDHA6 | protocadherin alpha 6 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PITX2 | paired-like homeodomain 2 |
| PMM1 | phosphomannomutase 1 |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRF1 | perforin 1 (pore forming protein) |
| PRKAA1 | protein kinase, AMP-activated, alpha 1 catalytic subunit |
| PRKX | protein kinase, X-linked |
| PRR15L | proline rich 15-like |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RBM4B | RNA binding motif protein 4B |
| RCOR3 | REST corepressor 3 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNF38 | ring finger protein 38 |
| RNF39 | ring finger protein 39 |
| SALL2 | spalt-like transcription factor 2 |
| SETD1A | SET domain containing 1A |
| SIX1 | SIX homeobox 1 |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| SP1 | Sp1 transcription factor |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| SYBU | syntabulin (syntaxin-interacting) |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TESK2 | testis-specific kinase 2 |
| THOP1 | thimet oligopeptidase 1 |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TRIM25 | tripartite motif containing 25 |
| TUBA4A | tubulin, alpha 4a |
| USP19 | ubiquitin specific peptidase 19 |
| USP20 | ubiquitin specific peptidase 20 |
| WDR4 | WD repeat domain 4 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZFHX2 | zinc finger homeobox 2 |
| ZKSCAN4 | zinc finger with KRAB and SCAN domains 4 |
| ZNF205 | zinc finger protein 205 |
| ZNF248 | zinc finger protein 248 |
| ZNF35 | zinc finger protein 35 |
| ZNF675 | zinc finger protein 675 |
| ZNF85 | zinc finger protein 85 |
