| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the mebendazole-3671 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AADAC | arylacetamide deacetylase |
| ADH1A | alcohol dehydrogenase 1A (class I), alpha polypeptide |
| AHSP | alpha hemoglobin stabilizing protein |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| ANGPTL2 | angiopoietin-like 2 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C22ORF24 | chromosome 22 open reading frame 24 |
| CAMSAP1 | calmodulin regulated spectrin-associated protein 1 |
| CD1E | CD1e molecule |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CFAP45 | cilia and flagella associated protein 45 |
| CHRNA1 | cholinergic receptor, nicotinic, alpha 1 (muscle) |
| CLDN18 | claudin 18 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DHRS12 | dehydrogenase/reductase (SDR family) member 12 |
| DSCC1 | DNA replication and sister chromatid cohesion 1 |
| DUSP1 | dual specificity phosphatase 1 |
| EDN1 | endothelin 1 |
| EMC3 | ER membrane protein complex subunit 3 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
| FST | follistatin |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GP6 | glycoprotein VI (platelet) |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B |
| GRIP2 | glutamate receptor interacting protein 2 |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HEPH | hephaestin |
| HIST1H3E | histone cluster 1, H3e |
| HR | hair growth associated |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IFT140 | intraflagellar transport 140 |
| IL11 | interleukin 11 |
| INSR | insulin receptor |
| ITIH4 | inter-alpha-trypsin inhibitor heavy chain family, member 4 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KRT34 | keratin 34, type I |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog |
| MFAP3L | microfibrillar-associated protein 3-like |
| MFI2 | antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 |
| MIP | major intrinsic protein of lens fiber |
| MMP28 | matrix metallopeptidase 28 |
| MPPE1 | metallophosphoesterase 1 |
| MVB12B | multivesicular body subunit 12B |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NEU3 | sialidase 3 (membrane sialidase) |
| NF1 | neurofibromin 1 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OGFR | opioid growth factor receptor |
| OR2B2 | olfactory receptor, family 2, subfamily B, member 2 |
| PADI2 | peptidyl arginine deiminase, type II |
| PDE8B | phosphodiesterase 8B |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| PER2 | period circadian clock 2 |
| PGLYRP4 | peptidoglycan recognition protein 4 |
| PHYHIP | phytanoyl-CoA 2-hydroxylase interacting protein |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| POU5F1B | POU class 5 homeobox 1B |
| PYY | peptide YY |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
| SH2D3A | SH2 domain containing 3A |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 |
| SLC22A1 | solute carrier family 22 (organic cation transporter), member 1 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SOX2 | SRY (sex determining region Y)-box 2 |
| SPHK2 | sphingosine kinase 2 |
| SPON2 | spondin 2, extracellular matrix protein |
| SRD5A2 | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) |
| STMN4 | stathmin-like 4 |
| STRN3 | striatin, calmodulin binding protein 3 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TBC1D1 | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 |
| TBCD | tubulin folding cofactor D |
| TBXAS1 | thromboxane A synthase 1 (platelet) |
| TCF7 | transcription factor 7 (T-cell specific, HMG-box) |
| TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain |
| TOP3B | topoisomerase (DNA) III beta |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TSHR | thyroid stimulating hormone receptor |
| TSKS | testis-specific serine kinase substrate |
| UST | uronyl-2-sulfotransferase |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZFHX2 | zinc finger homeobox 2 |
| ZFP64 | ZFP64 zinc finger protein |
| ZMAT4 | zinc finger, matrin-type 4 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| Symbol | Name |
|---|---|
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| BCL9 | B-cell CLL/lymphoma 9 |
| BCLAF1 | BCL2-associated transcription factor 1 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CA9 | carbonic anhydrase IX |
| CCDC106 | coiled-coil domain containing 106 |
| CISH | cytokine inducible SH2-containing protein |
| CNTFR | ciliary neurotrophic factor receptor |
| CORT | cortistatin |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CXORF56 | chromosome X open reading frame 56 |
| DBR1 | debranching RNA lariats 1 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 |
| FAM105A | family with sequence similarity 105, member A |
| FAM184A | family with sequence similarity 184, member A |
| FBXO3 | F-box protein 3 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| HIST1H2AG | histone cluster 1, H2ag |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H2BC | histone cluster 1, H2bc |
| HIST1H3G | histone cluster 1, H3g |
| HIST1H4E | histone cluster 1, H4e |
| HOXB9 | homeobox B9 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIAA1549L | KIAA1549-like |
| LAMC3 | laminin, gamma 3 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LOC390998 | ribosomal protein L10 pseudogene |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| LRRC61 | leucine rich repeat containing 61 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MAP3K7CL | MAP3K7 C-terminal like |
| MCTP2 | multiple C2 domains, transmembrane 2 |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MMP3 | matrix metallopeptidase 3 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| MYLIP | myosin regulatory light chain interacting protein |
| NID2 | nidogen 2 (osteonidogen) |
| NPFFR1 | neuropeptide FF receptor 1 |
| NUS1P3 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PALMD | palmdelphin |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRAMEF11 | PRAME family member 11 |
| PRR14L | proline rich 14-like |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RAB23 | RAB23, member RAS oncogene family |
| RAB3A | RAB3A, member RAS oncogene family |
| RBM4B | RNA binding motif protein 4B |
| RCOR3 | REST corepressor 3 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RPGR | retinitis pigmentosa GTPase regulator |
| RRAGB | Ras-related GTP binding B |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SESN1 | sestrin 1 |
| SETBP1 | SET binding protein 1 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SMO | smoothened, frizzled class receptor |
| SPATA7 | spermatogenesis associated 7 |
| SPC25 | SPC25, NDC80 kinetochore complex component |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| TENM4 | teneurin transmembrane protein 4 |
| THBS3 | thrombospondin 3 |
| TMEM180 | transmembrane protein 180 |
| TMEM53 | transmembrane protein 53 |
| TMSB15A | thymosin beta 15a |
| TRIM45 | tripartite motif containing 45 |
| TUBA1A | tubulin, alpha 1a |
| TUBA4A | tubulin, alpha 4a |
| TUBB3 | tubulin, beta 3 class III |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| VN1R1 | vomeronasal 1 receptor 1 |
| WDR41 | WD repeat domain 41 |
| WNT7A | wingless-type MMTV integration site family, member 7A |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF197 | zinc finger protein 197 |
| ZNF215 | zinc finger protein 215 |
| ZNF350 | zinc finger protein 350 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF665 | zinc finger protein 665 |
| ZNF74 | zinc finger protein 74 |
| ZNF76 | zinc finger protein 76 |
