| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the mebendazole-4694 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSBG1 | acyl-CoA synthetase bubblegum family member 1 |
| ADORA1 | adenosine A1 receptor |
| ALDOB | aldolase B, fructose-bisphosphate |
| ANO2 | anoctamin 2, calcium activated chloride channel |
| AQP3 | aquaporin 3 (Gill blood group) |
| AREG | amphiregulin |
| ARTN | artemin |
| ATF3 | activating transcription factor 3 |
| BDKRB2 | bradykinin receptor B2 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C11ORF16 | chromosome 11 open reading frame 16 |
| C16ORF45 | chromosome 16 open reading frame 45 |
| C5AR1 | complement component 5a receptor 1 |
| C8ORF4 | chromosome 8 open reading frame 4 |
| CCDC186 | coiled-coil domain containing 186 |
| CCDC33 | coiled-coil domain containing 33 |
| CDH5 | cadherin 5, type 2 (vascular endothelium) |
| CFAP69 | cilia and flagella associated protein 69 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLK3 | CDC-like kinase 3 |
| COL5A1 | collagen, type V, alpha 1 |
| CRISP2 | cysteine-rich secretory protein 2 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CTGF | connective tissue growth factor |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DCT | dopachrome tautomerase |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DUSP4 | dual specificity phosphatase 4 |
| EGR1 | early growth response 1 |
| ETV5 | ets variant 5 |
| FOSL1 | FOS-like antigen 1 |
| GPR1 | G protein-coupled receptor 1 |
| GPR37L1 | G protein-coupled receptor 37 like 1 |
| HBEGF | heparin-binding EGF-like growth factor |
| HLA-DRB6 | major histocompatibility complex, class II, DR beta 6 (pseudogene) |
| HOXB6 | homeobox B6 |
| HSD3B1 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
| ICAM1 | intercellular adhesion molecule 1 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IL5RA | interleukin 5 receptor, alpha |
| INHBE | inhibin, beta E |
| IRS2 | insulin receptor substrate 2 |
| ITGB6 | integrin, beta 6 |
| JUND | jun D proto-oncogene |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KIAA0125 | KIAA0125 |
| KIAA1456 | KIAA1456 |
| LIF | leukemia inhibitory factor |
| LOC157562 | uncharacterized LOC157562 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LRRN3 | leucine rich repeat neuronal 3 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MALL | mal, T-cell differentiation protein-like |
| MEFV | Mediterranean fever |
| NAV2 | neuron navigator 2 |
| NCAM1 | neural cell adhesion molecule 1 |
| NDE1 | nudE neurodevelopment protein 1 |
| NF2 | neurofibromin 2 (merlin) |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| ONECUT2 | one cut homeobox 2 |
| PAPPA2 | pappalysin 2 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDE8B | phosphodiesterase 8B |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLAUR | plasminogen activator, urokinase receptor |
| PLVAP | plasmalemma vesicle associated protein |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| POFUT1 | protein O-fucosyltransferase 1 |
| PTGES | prostaglandin E synthase |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RCE1 | Ras converting CAAX endopeptidase 1 |
| RSL1D1 | ribosomal L1 domain containing 1 |
| RUNX1 | runt-related transcription factor 1 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 |
| SMAD3 | SMAD family member 3 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPRY4 | sprouty homolog 4 (Drosophila) |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
| TEX14 | testis expressed 14 |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| THSD4 | thrombospondin, type I, domain containing 4 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TLR2 | toll-like receptor 2 |
| TMPRSS4 | transmembrane protease, serine 4 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| ZNF385D | zinc finger protein 385D |
| ZNF473 | zinc finger protein 473 |
| Symbol | Name |
|---|---|
| ABCA11P | ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) |
| ARMCX5 | armadillo repeat containing, X-linked 5 |
| ATG2B | autophagy related 2B |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BCL2L2 | BCL2-like 2 |
| BCLAF1 | BCL2-associated transcription factor 1 |
| BMP4 | bone morphogenetic protein 4 |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| CA2 | carbonic anhydrase II |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CRY2 | cryptochrome circadian clock 2 |
| DBR1 | debranching RNA lariats 1 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| FAM155A | family with sequence similarity 155, member A |
| FAM184A | family with sequence similarity 184, member A |
| FANCE | Fanconi anemia, complementation group E |
| FBXO3 | F-box protein 3 |
| FPGS | folylpolyglutamate synthase |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GHR | growth hormone receptor |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIRA | histone cell cycle regulator |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| IRS1 | insulin receptor substrate 1 |
| KIAA0894 | KIAA0894 protein |
| KRT31 | keratin 31, type I |
| KRT8P12 | keratin 8 pseudogene 12 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LYPD1 | LY6/PLAUR domain containing 1 |
| LYRM9 | LYR motif containing 9 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MCOLN3 | mucolipin 3 |
| MSANTD2 | Myb/SANT-like DNA-binding domain containing 2 |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NKX3-2 | NK3 homeobox 2 |
| NLK | nemo-like kinase |
| NLRX1 | NLR family member X1 |
| NUDT13 | nudix (nucleoside diphosphate linked moiety X)-type motif 13 |
| NXN | nucleoredoxin |
| ODF2 | outer dense fiber of sperm tails 2 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PCDHB3 | protocadherin beta 3 |
| PITX2 | paired-like homeodomain 2 |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| POLA2 | polymerase (DNA directed), alpha 2, accessory subunit |
| POM121 | POM121 transmembrane nucleoporin |
| PRR15L | proline rich 15-like |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RBM4B | RNA binding motif protein 4B |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| SALL2 | spalt-like transcription factor 2 |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SP140L | SP140 nuclear body protein-like |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TMEM184C | transmembrane protein 184C |
| TMUB2 | transmembrane and ubiquitin-like domain containing 2 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TRIM45 | tripartite motif containing 45 |
| TRIM52 | tripartite motif containing 52 |
| TSPYL4 | TSPY-like 4 |
| VASH2 | vasohibin 2 |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| WDR62 | WD repeat domain 62 |
| WDR76 | WD repeat domain 76 |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZKSCAN4 | zinc finger with KRAB and SCAN domains 4 |
| ZNF14 | zinc finger protein 14 |
| ZNF180 | zinc finger protein 180 |
| ZNF253 | zinc finger protein 253 |
| ZNF273 | zinc finger protein 273 |
| ZNF586 | zinc finger protein 586 |
| ZNF74 | zinc finger protein 74 |
| ZNF816 | zinc finger protein 816 |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |
| ZXDC | ZXD family zinc finger C |
