| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the mebendazole-7370 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| ANKMY1 | ankyrin repeat and MYND domain containing 1 |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ARIH2 | ariadne RBR E3 ubiquitin protein ligase 2 |
| ARMC8 | armadillo repeat containing 8 |
| C1ORF116 | chromosome 1 open reading frame 116 |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit |
| CACYBP | calcyclin binding protein |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CES2 | carboxylesterase 2 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) |
| CLDN11 | claudin 11 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 |
| CNN2 | calponin 2 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DCTN1 | dynactin 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DSC2 | desmocollin 2 |
| DUSP1 | dual specificity phosphatase 1 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| FAS | Fas cell surface death receptor |
| FBN2 | fibrillin 2 |
| FST | follistatin |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GPR161 | G protein-coupled receptor 161 |
| HBEGF | heparin-binding EGF-like growth factor |
| HMHA1 | histocompatibility (minor) HA-1 |
| HOXC4 | homeobox C4 |
| HS1BP3 | HCLS1 binding protein 3 |
| HSF1 | heat shock transcription factor 1 |
| IL11 | interleukin 11 |
| IL32 | interleukin 32 |
| IL6 | interleukin 6 |
| INO80B | INO80 complex subunit B |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KDM2A | lysine (K)-specific demethylase 2A |
| KLF6 | Kruppel-like factor 6 |
| KRBOX4 | KRAB box domain containing 4 |
| KRT34 | keratin 34, type I |
| KRT6B | keratin 6B, type II |
| LIG3 | ligase III, DNA, ATP-dependent |
| LIN7C | lin-7 homolog C (C. elegans) |
| LINC00260 | long intergenic non-protein coding RNA 260 |
| LPIN1 | lipin 1 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MYOZ3 | myozenin 3 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NF2 | neurofibromin 2 (merlin) |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| ORC5 | origin recognition complex, subunit 5 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PAPOLA | poly(A) polymerase alpha |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PDLIM5 | PDZ and LIM domain 5 |
| PPP1R3D | protein phosphatase 1, regulatory subunit 3D |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PSKH1 | protein serine kinase H1 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RBM12B | RNA binding motif protein 12B |
| RGS4 | regulator of G-protein signaling 4 |
| RPL28 | ribosomal protein L28 |
| S1PR1 | sphingosine-1-phosphate receptor 1 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SEC31A | SEC31 homolog A (S. cerevisiae) |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SMC4 | structural maintenance of chromosomes 4 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SND1-IT1 | SND1 intronic transcript 1 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SPATA2L | spermatogenesis associated 2-like |
| STC1 | stanniocalcin 1 |
| SYT1 | synaptotagmin I |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TAGLN3 | transgelin 3 |
| TAOK1 | TAO kinase 1 |
| TENM1 | teneurin transmembrane protein 1 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| TLN2 | talin 2 |
| TMEM242 | transmembrane protein 242 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRIB3 | tribbles pseudokinase 3 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TSFM | Ts translation elongation factor, mitochondrial |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF606 | zinc finger protein 606 |
| Symbol | Name |
|---|---|
| ADGRF1 | adhesion G protein-coupled receptor F1 |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BBS10 | Bardet-Biedl syndrome 10 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| C11ORF68 | chromosome 11 open reading frame 68 |
| C16ORF62 | chromosome 16 open reading frame 62 |
| CCNE1 | cyclin E1 |
| CDH7 | cadherin 7, type 2 |
| CDK3 | cyclin-dependent kinase 3 |
| CEP70 | centrosomal protein 70kDa |
| CHEK2 | checkpoint kinase 2 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CPA4 | carboxypeptidase A4 |
| CTSK | cathepsin K |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| EHD3 | EH-domain containing 3 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| EPN3 | epsin 3 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FRAT2 | frequently rearranged in advanced T-cell lymphomas 2 |
| GALK1 | galactokinase 1 |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GRAMD4 | GRAM domain containing 4 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2BJ | histone cluster 1, H2bj |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| IRF9 | interferon regulatory factor 9 |
| KIAA0513 | KIAA0513 |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| MAGEF1 | melanoma antigen family F1 |
| MAP1S | microtubule-associated protein 1S |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MMP1 | matrix metallopeptidase 1 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MON1B | MON1 secretory trafficking family member B |
| MOXD1 | monooxygenase, DBH-like 1 |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| MYO1D | myosin ID |
| NBEAL2 | neurobeachin-like 2 |
| NOL12 | nucleolar protein 12 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PLCD1 | phospholipase C, delta 1 |
| POMT1 | protein-O-mannosyltransferase 1 |
| PPP2R2D | protein phosphatase 2, regulatory subunit B, delta |
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 |
| RCOR3 | REST corepressor 3 |
| RGS17 | regulator of G-protein signaling 17 |
| RIN1 | Ras and Rab interactor 1 |
| RNF2 | ring finger protein 2 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| SAMD9 | sterile alpha motif domain containing 9 |
| SCARA3 | scavenger receptor class A, member 3 |
| SETBP1 | SET binding protein 1 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| SLC35E3 | solute carrier family 35, member E3 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SMAD7 | SMAD family member 7 |
| SMYD3 | SET and MYND domain containing 3 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 |
| TASP1 | taspase, threonine aspartase, 1 |
| TMEM53 | transmembrane protein 53 |
| TRIM13 | tripartite motif containing 13 |
| TRIM21 | tripartite motif containing 21 |
| TRIM9 | tripartite motif containing 9 |
| TUBA1A | tubulin, alpha 1a |
| TUBA4A | tubulin, alpha 4a |
| TUBB | tubulin, beta class I |
| TUBB3 | tubulin, beta 3 class III |
| TUBB4B | tubulin, beta 4B class IVb |
| TXLNG | taxilin gamma |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZKSCAN4 | zinc finger with KRAB and SCAN domains 4 |
| ZNF230 | zinc finger protein 230 |
| ZNF253 | zinc finger protein 253 |
| ZNF350 | zinc finger protein 350 |
| ZNF574 | zinc finger protein 574 |
| ZNF675 | zinc finger protein 675 |
| ZNF816 | zinc finger protein 816 |
| ZNF84 | zinc finger protein 84 |
| ZXDC | ZXD family zinc finger C |
