mebeverine-1576 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the mebeverine-1576 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACP6 acid phosphatase 6, lysophosphatidic
ACVRL1 activin A receptor type II-like 1
AGRP agouti related neuropeptide
AKAP8L A kinase (PRKA) anchor protein 8-like
ALPK1 alpha-kinase 1
ANKRD12 ankyrin repeat domain 12
ANKRD46 ankyrin repeat domain 46
AXIN1 axin 1
BAD BCL2-associated agonist of cell death
CCPG1 cell cycle progression 1
CEP152 centrosomal protein 152kDa
CEP70 centrosomal protein 70kDa
CIITA class II, major histocompatibility complex, transactivator
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
CTRL chymotrypsin-like
CYB561 cytochrome b561
DEAF1 DEAF1 transcription factor
DUSP2 dual specificity phosphatase 2
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
ELAC2 elaC ribonuclease Z 2
ELK1 ELK1, member of ETS oncogene family
ERC1 ELKS/RAB6-interacting/CAST family member 1
ETV5 ets variant 5
FAM13A family with sequence similarity 13, member A
FAM57A family with sequence similarity 57, member A
FKBP1A FK506 binding protein 1A, 12kDa
FOLR1 folate receptor 1 (adult)
FSCN1 fascin actin-bundling protein 1
FSCN3 fascin actin-bundling protein 3, testicular
FYB FYN binding protein
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GCKR glucokinase (hexokinase 4) regulator
GIMAP5 GTPase, IMAP family member 5
GPSM3 G-protein signaling modulator 3
GRK6 G protein-coupled receptor kinase 6
GSK3A glycogen synthase kinase 3 alpha
GSS glutathione synthetase
HCAR3 hydroxycarboxylic acid receptor 3
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HOXA10 homeobox A10
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IGFBP7 insulin-like growth factor binding protein 7
IL1RAP interleukin 1 receptor accessory protein
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KIAA1109 KIAA1109
KIFC1 kinesin family member C1
KPNB1 karyopherin (importin) beta 1
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LMAN2L lectin, mannose-binding 2-like
MAP4 microtubule-associated protein 4
MYL10 myosin, light chain 10, regulatory
N4BP1 NEDD4 binding protein 1
NBN nibrin
NDRG2 NDRG family member 2
NR2F2 nuclear receptor subfamily 2, group F, member 2
NXPH3 neurexophilin 3
PCSK7 proprotein convertase subtilisin/kexin type 7
PELI2 pellino E3 ubiquitin protein ligase family member 2
PIGV phosphatidylinositol glycan anchor biosynthesis, class V
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLCD1 phospholipase C, delta 1
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PTMA prothymosin, alpha
RBM3 RNA binding motif (RNP1, RRM) protein 3
RECQL4 RecQ protein-like 4
RNASE3 ribonuclease, RNase A family, 3
RNGTT RNA guanylyltransferase and 5'-phosphatase
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPHS1 selenophosphate synthetase 1
SH3GL1 SH3-domain GRB2-like 1
SKAP1 src kinase associated phosphoprotein 1
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SOCS2 suppressor of cytokine signaling 2
SON SON DNA binding protein
SPATA5L1 spermatogenesis associated 5-like 1
SPN sialophorin
TBC1D22A TBC1 domain family, member 22A
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TM2D1 TM2 domain containing 1
TMEM127 transmembrane protein 127
TPT1 tumor protein, translationally-controlled 1
TRAIP TRAF interacting protein
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TUBB3 tubulin, beta 3 class III
UBE2L3 ubiquitin-conjugating enzyme E2L 3
UBQLN4 ubiquilin 4
USF2 upstream transcription factor 2, c-fos interacting
WDR48 WD repeat domain 48
ZMYM2 zinc finger, MYM-type 2
ZNF124 zinc finger protein 124
ZNF280D zinc finger protein 280D
ZNF408 zinc finger protein 408
ZNF574 zinc finger protein 574
ZSWIM8 zinc finger, SWIM-type containing 8

decreased expression

Symbol Name
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ABHD11 abhydrolase domain containing 11
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADAM23 ADAM metallopeptidase domain 23
AGO2 argonaute RISC catalytic component 2
APH1B APH1B gamma secretase subunit
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASAP1-IT1 ASAP1 intronic transcript 1
BRPF1 bromodomain and PHD finger containing, 1
C12ORF4 chromosome 12 open reading frame 4
C19ORF54 chromosome 19 open reading frame 54
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
C5ORF22 chromosome 5 open reading frame 22
CAMTA2 calmodulin binding transcription activator 2
CD248 CD248 molecule, endosialin
CD82 CD82 molecule
CER1 cerberus 1, DAN family BMP antagonist
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CIDEC cell death-inducing DFFA-like effector c
CIR1 corepressor interacting with RBPJ, 1
CRYL1 crystallin, lambda 1
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
DHDDS dehydrodolichyl diphosphate synthase
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DPF2 D4, zinc and double PHD fingers family 2
DRD5 dopamine receptor D5
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1
FAM188A family with sequence similarity 188, member A
FAM50B family with sequence similarity 50, member B
GBAP1 glucosidase, beta, acid pseudogene 1
GMIP GEM interacting protein
GOLGA3 golgin A3
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1
INO80D INO80 complex subunit D
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
KCTD15 potassium channel tetramerization domain containing 15
KDM5C lysine (K)-specific demethylase 5C
KIAA0894 KIAA0894 protein
KPNA4 karyopherin alpha 4 (importin alpha 3)
LYPLA2P1 lysophospholipase II pseudogene 1
MAP1S microtubule-associated protein 1S
MEAF6 MYST/Esa1-associated factor 6
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MID1IP1 MID1 interacting protein 1
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MNAT1 MNAT CDK-activating kinase assembly factor 1
MNS1 meiosis-specific nuclear structural 1
MTG1 mitochondrial ribosome-associated GTPase 1
MX2 MX dynamin-like GTPase 2
MYL12B myosin, light chain 12B, regulatory
MYO9A myosin IXA
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1
NCOA4 nuclear receptor coactivator 4
NMB neuromedin B
NPIPB15 nuclear pore complex interacting protein family, member B15
NR1D2 nuclear receptor subfamily 1, group D, member 2
NSUN3 NOP2/Sun domain family, member 3
NUCB2 nucleobindin 2
PADI1 peptidyl arginine deiminase, type I
PAQR3 progestin and adipoQ receptor family member III
PARPBP PARP1 binding protein
PCDHGB5 protocadherin gamma subfamily B, 5
PHLDA2 pleckstrin homology-like domain, family A, member 2
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PNRC1 proline-rich nuclear receptor coactivator 1
POTEKP POTE ankyrin domain family, member K, pseudogene
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
RBM47 RNA binding motif protein 47
RCL1 RNA terminal phosphate cyclase-like 1
RIC8A RIC8 guanine nucleotide exchange factor A
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SFXN1 sideroflexin 1
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMG8 SMG8 nonsense mediated mRNA decay factor
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
STEAP3 STEAP family member 3, metalloreductase
STRA13 stimulated by retinoic acid 13
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
TAC3 tachykinin 3
THOP1 thimet oligopeptidase 1
THUMPD2 THUMP domain containing 2
TIPIN TIMELESS interacting protein
TMEM11 transmembrane protein 11
TRIM45 tripartite motif containing 45
TRIM5 tripartite motif containing 5
TSLIG2 tRNA splicing ligase complex subunit 2
TTBK2 tau tubulin kinase 2
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
USP6 ubiquitin specific peptidase 6
YIPF1 Yip1 domain family, member 1
ZBTB39 zinc finger and BTB domain containing 39
ZNF197 zinc finger protein 197
ZNF211 zinc finger protein 211
ZNF212 zinc finger protein 212