mebeverine-3193 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the mebeverine-3193 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ADAM22 ADAM metallopeptidase domain 22
ADH6 alcohol dehydrogenase 6 (class V)
AGER advanced glycosylation end product-specific receptor
AMPD3 adenosine monophosphate deaminase 3
ANG angiogenin, ribonuclease, RNase A family, 5
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
BIN1 bridging integrator 1
BTF3P11 basic transcription factor 3 pseudogene 11
C10ORF12 chromosome 10 open reading frame 12
CCDC102B coiled-coil domain containing 102B
CD1A CD1a molecule
CD226 CD226 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD70 CD70 molecule
CDC25A cell division cycle 25A
CGA glycoprotein hormones, alpha polypeptide
CLEC10A C-type lectin domain family 10, member A
COMMD4 COMM domain containing 4
CSHL1 chorionic somatomammotropin hormone-like 1
CST1 cystatin SN
CTSE cathepsin E
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
DDO D-aspartate oxidase
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DEFA5 defensin, alpha 5, Paneth cell-specific
DSPP dentin sialophosphoprotein
EFHC2 EF-hand domain (C-terminal) containing 2
EMC3 ER membrane protein complex subunit 3
FBXO40 F-box protein 40
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCMR Fc fragment of IgM receptor
FPR1 formyl peptide receptor 1
GAS7 growth arrest-specific 7
GLIPR1 GLI pathogenesis-related 1
GLS2 glutaminase 2 (liver, mitochondrial)
GPR27 G protein-coupled receptor 27
GREM2 gremlin 2, DAN family BMP antagonist
HERC2P3 hect domain and RLD 2 pseudogene 3
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LPCAT4 lysophosphatidylcholine acyltransferase 4
MLLT4-AS1 MLLT4 antisense RNA 1 (head to head)
MOCS1 molybdenum cofactor synthesis 1
MTSS1L metastasis suppressor 1-like
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MZF1 myeloid zinc finger 1
NEURL1 neuralized E3 ubiquitin protein ligase 1
NPR1 natriuretic peptide receptor 1
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PDE4B phosphodiesterase 4B, cAMP-specific
PDLIM5 PDZ and LIM domain 5
PHC3 polyhomeotic homolog 3 (Drosophila)
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PRKCQ protein kinase C, theta
PRKD1 protein kinase D1
PRSS50 protease, serine, 50
PTGDR2 prostaglandin D2 receptor 2
RAB33A RAB33A, member RAS oncogene family
RASAL2 RAS protein activator like 2
RPH3A rabphilin 3A
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SLURP1 secreted LY6/PLAUR domain containing 1
SNTA1 syntrophin, alpha 1
SPAG8 sperm associated antigen 8
SPTBN2 spectrin, beta, non-erythrocytic 2
SYN3 synapsin III
TECPR2 tectonin beta-propeller repeat containing 2
TEF thyrotrophic embryonic factor
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFDP3 transcription factor Dp family, member 3
TK2 thymidine kinase 2, mitochondrial
TLE4 transducin-like enhancer of split 4
TM4SF1 transmembrane 4 L six family member 1
TPMT thiopurine S-methyltransferase
TRDMT1 tRNA aspartic acid methyltransferase 1
TREM2 triggering receptor expressed on myeloid cells 2
TSNAXIP1 translin-associated factor X interacting protein 1
TTC28 tetratricopeptide repeat domain 28
TTN titin
UBE2B ubiquitin-conjugating enzyme E2B
USP22 ubiquitin specific peptidase 22
USP29 ubiquitin specific peptidase 29
VCAN versican
WDR4 WD repeat domain 4
WNT3 wingless-type MMTV integration site family, member 3
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF214 zinc finger protein 214
ZNF358 zinc finger protein 358
ZNF507 zinc finger protein 507

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ADCY7 adenylate cyclase 7
ADGRG2 adhesion G protein-coupled receptor G2
AFAP1 actin filament associated protein 1
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ASPHD1 aspartate beta-hydroxylase domain containing 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BAHCC1 BAH domain and coiled-coil containing 1
CAMKV CaM kinase-like vesicle-associated
CAPN15 calpain 15
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCDC69 coiled-coil domain containing 69
CCDC88C coiled-coil domain containing 88C
CCNK cyclin K
CD53 CD53 molecule
CFD complement factor D (adipsin)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHST10 carbohydrate sulfotransferase 10
CLCF1 cardiotrophin-like cytokine factor 1
CRYBG3 beta-gamma crystallin domain containing 3
CSF1R colony stimulating factor 1 receptor
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DCAF13 DDB1 and CUL4 associated factor 13
DNAH17 dynein, axonemal, heavy chain 17
DNAL4 dynein, axonemal, light chain 4
DYSF dysferlin
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ELOVL4 ELOVL fatty acid elongase 4
EXOC6B exocyst complex component 6B
FAM189A2 family with sequence similarity 189, member A2
FAM86C1 family with sequence similarity 86, member C1
FBXO4 F-box protein 4
FKBP8 FK506 binding protein 8, 38kDa
FLCN folliculin
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GBP2 guanylate binding protein 2, interferon-inducible
GMPR guanosine monophosphate reductase
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNG4 guanine nucleotide binding protein (G protein), gamma 4
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HOXC5 homeobox C5
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IDI2-AS1 IDI2 antisense RNA 1
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL17RA interleukin 17 receptor A
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KCTD7 potassium channel tetramerization domain containing 7
KRT83 keratin 83, type II
LATS1 large tumor suppressor kinase 1
LDHB lactate dehydrogenase B
LOC729164 hCG1732469
LYZ lysozyme
MEIS1 Meis homeobox 1
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
NAT6 N-acetyltransferase 6 (GCN5-related)
NDE1 nudE neurodevelopment protein 1
NEUROD4 neuronal differentiation 4
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NHEJ1 nonhomologous end-joining factor 1
NLRX1 NLR family member X1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PCDHA5 protocadherin alpha 5
PECR peroxisomal trans-2-enoyl-CoA reductase
PHC1 polyhomeotic homolog 1 (Drosophila)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLD2 phospholipase D2
POLL polymerase (DNA directed), lambda
PPT2 palmitoyl-protein thioesterase 2
PRSS22 protease, serine, 22
PTK6 protein tyrosine kinase 6
QSER1 glutamine and serine rich 1
RPL10L ribosomal protein L10-like
SCAI suppressor of cancer cell invasion
SCGB2A2 secretoglobin, family 2A, member 2
SCNN1B sodium channel, non voltage gated 1 beta subunit
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SLC12A9 solute carrier family 12, member 9
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC22A14 solute carrier family 22, member 14
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SND1-IT1 SND1 intronic transcript 1
SPRY2 sprouty homolog 2 (Drosophila)
SRD5A3 steroid 5 alpha-reductase 3
SRGN serglycin
ST5 suppression of tumorigenicity 5
STARD5 StAR-related lipid transfer (START) domain containing 5
TCTN2 tectonic family member 2
TIGD6 tigger transposable element derived 6
TMEM120B transmembrane protein 120B
TSC22D4 TSC22 domain family, member 4
ULBP2 UL16 binding protein 2
ZBTB6 zinc finger and BTB domain containing 6
ZNF227 zinc finger protein 227
ZNF768 zinc finger protein 768
ZSCAN2 zinc finger and SCAN domain containing 2