mebeverine-6795 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

192 genes differentially expressed following the mebeverine-6795 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
ADARB1 adenosine deaminase, RNA-specific, B1
AKR1C1 aldo-keto reductase family 1, member C1
ARHGAP44 Rho GTPase activating protein 44
ARID1A AT rich interactive domain 1A (SWI-like)
ATF7IP activating transcription factor 7 interacting protein
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
C1ORF105 chromosome 1 open reading frame 105
CALCOCO1 calcium binding and coiled-coil domain 1
CALD1 caldesmon 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CDK14 cyclin-dependent kinase 14
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CHKB choline kinase beta
CLCN6 chloride channel, voltage-sensitive 6
COL4A1 collagen, type IV, alpha 1
CROCC ciliary rootlet coiled-coil, rootletin
DAPK2 death-associated protein kinase 2
DBN1 drebrin 1
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOCK9 dedicator of cytokinesis 9
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DRD2 dopamine receptor D2
DUSP9 dual specificity phosphatase 9
EDEM3 ER degradation enhancer, mannosidase alpha-like 3
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
EWSR1 EWS RNA-binding protein 1
FAM174B family with sequence similarity 174, member B
FCMR Fc fragment of IgM receptor
FLJ22184
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GIMAP6 GTPase, IMAP family member 6
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPR153 G protein-coupled receptor 153
GPR4 G protein-coupled receptor 4
HFE hemochromatosis
HIST1H2BO histone cluster 1, H2bo
HLA-DMB major histocompatibility complex, class II, DM beta
IL6R interleukin 6 receptor
IQCC IQ motif containing C
IRF8 interferon regulatory factor 8
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGB6 integrin, beta 6
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KIAA0040 KIAA0040
KLHL25 kelch-like family member 25
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LMF2 lipase maturation factor 2
MAGEB2 melanoma antigen family B2
MAGOH2P mago-nashi homolog 2, pseudogene
MAP1S microtubule-associated protein 1S
MAST4 microtubule associated serine/threonine kinase family member 4
MBNL3 muscleblind-like splicing regulator 3
MRC2 mannose receptor, C type 2
MYL10 myosin, light chain 10, regulatory
NLE1 notchless homolog 1 (Drosophila)
NOD1 nucleotide-binding oligomerization domain containing 1
NPTX1 neuronal pentraxin I
NRSN2 neurensin 2
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
PCDHA9 protocadherin alpha 9
PGAP1 post-GPI attachment to proteins 1
PLIN2 perilipin 2
PLK3 polo-like kinase 3
PPARD peroxisome proliferator-activated receptor delta
PSD3 pleckstrin and Sec7 domain containing 3
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RERE arginine-glutamic acid dipeptide (RE) repeats
RUSC2 RUN and SH3 domain containing 2
SCAND2P SCAN domain containing 2 pseudogene
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
SLC14A2 solute carrier family 14 (urea transporter), member 2
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SMIM14 small integral membrane protein 14
SPAG8 sperm associated antigen 8
SPTAN1 spectrin, alpha, non-erythrocytic 1
STAT2 signal transducer and activator of transcription 2, 113kDa
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TAPBP TAP binding protein (tapasin)
TGFBR3 transforming growth factor, beta receptor III
THBS1 thrombospondin 1
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TPM3 tropomyosin 3
UBA7 ubiquitin-like modifier activating enzyme 7
UBOX5 U-box domain containing 5
UPK3B uroplakin 3B
USP20 ubiquitin specific peptidase 20
VNN2 vanin 2
WNT10B wingless-type MMTV integration site family, member 10B
XYLB xylulokinase homolog (H. influenzae)
YOD1 YOD1 deubiquitinase
ZBED1 zinc finger, BED-type containing 1
ZNF280B zinc finger protein 280B

decreased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AKAP12 A kinase (PRKA) anchor protein 12
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASPHD1 aspartate beta-hydroxylase domain containing 1
B9D2 B9 protein domain 2
BGLAP bone gamma-carboxyglutamate (gla) protein
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CBR4 carbonyl reductase 4
CBX8 chromobox homolog 8
CCDC88C coiled-coil domain containing 88C
CCNE1 cyclin E1
CEP97 centrosomal protein 97kDa
CORO7 coronin 7
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DGAT1 diacylglycerol O-acyltransferase 1
DUSP5 dual specificity phosphatase 5
EAF2 ELL associated factor 2
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
FAAH fatty acid amide hydrolase
FAM188A family with sequence similarity 188, member A
FBXO31 F-box protein 31
FIP1L1 factor interacting with PAPOLA and CPSF1
FRS2 fibroblast growth factor receptor substrate 2
GAMT guanidinoacetate N-methyltransferase
GAREM GRB2 associated, regulator of MAPK1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNL1 guanine nucleotide binding protein-like 1
GPR27 G protein-coupled receptor 27
GPX2 glutathione peroxidase 2
GSTM2 glutathione S-transferase mu 2 (muscle)
HDAC7 histone deacetylase 7
HIST1H2AE histone cluster 1, H2ae
HIST1H2AJ histone cluster 1, H2aj
HIST2H2AA3 histone cluster 2, H2aa3
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HTRA1 HtrA serine peptidase 1
IFI6 interferon, alpha-inducible protein 6
IRAK4 interleukin-1 receptor-associated kinase 4
KDM8 lysine (K)-specific demethylase 8
KIAA0125 KIAA0125
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LGALS4 lectin, galactoside-binding, soluble, 4
LIF leukemia inhibitory factor
LY6E lymphocyte antigen 6 complex, locus E
LZTR1 leucine-zipper-like transcription regulator 1
MAGOHB mago-nashi homolog B (Drosophila)
MAPKBP1 mitogen-activated protein kinase binding protein 1
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MFAP2 microfibrillar-associated protein 2
MMP9 matrix metallopeptidase 9
MRPL44 mitochondrial ribosomal protein L44
MVP major vault protein
NDE1 nudE neurodevelopment protein 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NIPAL2 NIPA-like domain containing 2
NNAT neuronatin
PAQR6 progestin and adipoQ receptor family member VI
PARP12 poly (ADP-ribose) polymerase family, member 12
PCDH12 protocadherin 12
PGP phosphoglycolate phosphatase
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLXNA3 plexin A3
PMP22 peripheral myelin protein 22
PPT2 palmitoyl-protein thioesterase 2
PRODH proline dehydrogenase (oxidase) 1
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB23 RAB23, member RAS oncogene family
RASAL1 RAS protein activator like 1 (GAP1 like)
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RGS2 regulator of G-protein signaling 2
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPRR2B small proline-rich protein 2B
STARD5 StAR-related lipid transfer (START) domain containing 5
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TCTN2 tectonic family member 2
TFPI2 tissue factor pathway inhibitor 2
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM209 transmembrane protein 209
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRAIP TRAF interacting protein
TSPAN14 tetraspanin 14
TXNL4B thioredoxin-like 4B
UBQLN4 ubiquilin 4
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WDR91 WD repeat domain 91
YY2 YY2 transcription factor
ZNF227 zinc finger protein 227
ZNF239 zinc finger protein 239
ZNF286A zinc finger protein 286A