mebeverine-7147 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the mebeverine-7147 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ADCK2 aarF domain containing kinase 2
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARMC9 armadillo repeat containing 9
ARNT aryl hydrocarbon receptor nuclear translocator
BTN3A1 butyrophilin, subfamily 3, member A1
C4ORF29 chromosome 4 open reading frame 29
C7ORF43 chromosome 7 open reading frame 43
CALML4 calmodulin-like 4
CASKIN2 CASK interacting protein 2
CCNJL cyclin J-like
CDK10 cyclin-dependent kinase 10
CFDP1 craniofacial development protein 1
CGREF1 cell growth regulator with EF-hand domain 1
CHD7 chromodomain helicase DNA binding protein 7
CLDN1 claudin 1
CNTNAP2 contactin associated protein-like 2
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CUL9 cullin 9
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DOCK9 dedicator of cytokinesis 9
EGF epidermal growth factor
EIF3M eukaryotic translation initiation factor 3, subunit M
ELP6 elongator acetyltransferase complex subunit 6
EPOR erythropoietin receptor
ERAP2 endoplasmic reticulum aminopeptidase 2
ERN2 endoplasmic reticulum to nucleus signaling 2
EVI5 ecotropic viral integration site 5
FAM188A family with sequence similarity 188, member A
FCMR Fc fragment of IgM receptor
FKBP8 FK506 binding protein 8, 38kDa
FOXO1 forkhead box O1
FYN FYN proto-oncogene, Src family tyrosine kinase
GATA3 GATA binding protein 3
GK glycerol kinase
GREM1 gremlin 1, DAN family BMP antagonist
H2AFX H2A histone family, member X
HOXA4 homeobox A4
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KIAA0319L KIAA0319-like
LIMS2 LIM and senescent cell antigen-like domains 2
LPIN2 lipin 2
MAP1S microtubule-associated protein 1S
MAP4 microtubule-associated protein 4
MAPT microtubule-associated protein tau
MAST3 microtubule associated serine/threonine kinase 3
MAST4 microtubule associated serine/threonine kinase family member 4
MFGE8 milk fat globule-EGF factor 8 protein
MTAP methylthioadenosine phosphorylase
MYO9A myosin IXA
N4BP1 NEDD4 binding protein 1
NDE1 nudE neurodevelopment protein 1
OPTN optineurin
PARVA parvin, alpha
PBX2 pre-B-cell leukemia homeobox 2
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PRDX2 peroxiredoxin 2
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PRMT2IP PRMT2 interacting protein
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PTPRH protein tyrosine phosphatase, receptor type, H
RAB33B RAB33B, member RAS oncogene family
RANGAP1 Ran GTPase activating protein 1
RERE arginine-glutamic acid dipeptide (RE) repeats
RUNDC3B RUN domain containing 3B
RUNX3 runt-related transcription factor 3
RUSC2 RUN and SH3 domain containing 2
SEC24D SEC24 family member D
SETDB1 SET domain, bifurcated 1
SIPA1L3 signal-induced proliferation-associated 1 like 3
SIRT6 sirtuin 6
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SPATA2L spermatogenesis associated 2-like
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
STAC SH3 and cysteine rich domain
STAG3 stromal antigen 3
STC1 stanniocalcin 1
STRN4 striatin, calmodulin binding protein 4
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TDRKH tudor and KH domain containing
TESPA1 thymocyte expressed, positive selection associated 1
TMEM80 transmembrane protein 80
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNIK TRAF2 and NCK interacting kinase
TPRA1 transmembrane protein, adipocyte asscociated 1
TRIM2 tripartite motif containing 2
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF224 zinc finger protein 224
ZNF318 zinc finger protein 318
ZNF512B zinc finger protein 512B
ZSCAN32 zinc finger and SCAN domain containing 32

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ACTG2 actin, gamma 2, smooth muscle, enteric
ADM adrenomedullin
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
AVPI1 arginine vasopressin-induced 1
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BCL2A1 BCL2-related protein A1
C9ORF91 chromosome 9 open reading frame 91
CALCOCO1 calcium binding and coiled-coil domain 1
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBY1 chibby homolog 1 (Drosophila)
CCDC68 coiled-coil domain containing 68
CIR1 corepressor interacting with RBPJ, 1
CPEB1 cytoplasmic polyadenylation element binding protein 1
CXCL2 chemokine (C-X-C motif) ligand 2
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DESI1 desumoylating isopeptidase 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
EDC3 enhancer of mRNA decapping 3
EDIL3 EGF-like repeats and discoidin I-like domains 3
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM193B family with sequence similarity 193, member B
FAM86C1 family with sequence similarity 86, member C1
FGD1 FYVE, RhoGEF and PH domain containing 1
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
HIRA histone cell cycle regulator
HSPA2 heat shock 70kDa protein 2
IFI6 interferon, alpha-inducible protein 6
IFT54 intraflagellar transport 54
IL17RA interleukin 17 receptor A
INCENP inner centromere protein antigens 135/155kDa
IPO8 importin 8
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
KCTD15 potassium channel tetramerization domain containing 15
KCTD20 potassium channel tetramerization domain containing 20
LINC00341 long intergenic non-protein coding RNA 341
LTBP2 latent transforming growth factor beta binding protein 2
LYPD1 LY6/PLAUR domain containing 1
LZTR1 leucine-zipper-like transcription regulator 1
MANEA mannosidase, endo-alpha
METTL16 methyltransferase like 16
MNX1 motor neuron and pancreas homeobox 1
MOB3B MOB kinase activator 3B
MYLK myosin light chain kinase
NCS1 neuronal calcium sensor 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NECAB3 N-terminal EF-hand calcium binding protein 3
NID2 nidogen 2 (osteonidogen)
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
OPLAH 5-oxoprolinase (ATP-hydrolysing)
OSMR oncostatin M receptor
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PARD6A par-6 family cell polarity regulator alpha
PCSK7 proprotein convertase subtilisin/kexin type 7
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLA2G15 phospholipase A2, group XV
PLAC8 placenta-specific 8
PLEKHO1 pleckstrin homology domain containing, family O member 1
POLL polymerase (DNA directed), lambda
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRMT7 protein arginine methyltransferase 7
PSENEN presenilin enhancer gamma secretase subunit
ROGDI rogdi homolog (Drosophila)
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RUNX1-IT1 RUNX1 intronic transcript 1
SCML2 sex comb on midleg-like 2 (Drosophila)
SENP7 SUMO1/sentrin specific peptidase 7
SETD8 SET domain containing (lysine methyltransferase) 8
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STK16 serine/threonine kinase 16
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TBX19 T-box 19
TGS1 trimethylguanosine synthase 1
THAP10 THAP domain containing 10
THBS3 thrombospondin 3
TMEM242 transmembrane protein 242
TPST2 tyrosylprotein sulfotransferase 2
TRIM16 tripartite motif containing 16
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TUBA3C tubulin, alpha 3c
ULBP2 UL16 binding protein 2
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
YOD1 YOD1 deubiquitinase
ZKSCAN4 zinc finger with KRAB and SCAN domains 4
ZNF250 zinc finger protein 250
ZNF415 zinc finger protein 415
ZNF770 zinc finger protein 770
ZXDC ZXD family zinc finger C