| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the mebeverine-7147 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCF2 | ATP-binding cassette, sub-family F (GCN20), member 2 |
| ADCK2 | aarF domain containing kinase 2 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
| ARMC9 | armadillo repeat containing 9 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| BTN3A1 | butyrophilin, subfamily 3, member A1 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CALML4 | calmodulin-like 4 |
| CASKIN2 | CASK interacting protein 2 |
| CCNJL | cyclin J-like |
| CDK10 | cyclin-dependent kinase 10 |
| CFDP1 | craniofacial development protein 1 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHD7 | chromodomain helicase DNA binding protein 7 |
| CLDN1 | claudin 1 |
| CNTNAP2 | contactin associated protein-like 2 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
| CUL9 | cullin 9 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| DOCK9 | dedicator of cytokinesis 9 |
| EGF | epidermal growth factor |
| EIF3M | eukaryotic translation initiation factor 3, subunit M |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EPOR | erythropoietin receptor |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EVI5 | ecotropic viral integration site 5 |
| FAM188A | family with sequence similarity 188, member A |
| FCMR | Fc fragment of IgM receptor |
| FKBP8 | FK506 binding protein 8, 38kDa |
| FOXO1 | forkhead box O1 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase |
| GATA3 | GATA binding protein 3 |
| GK | glycerol kinase |
| GREM1 | gremlin 1, DAN family BMP antagonist |
| H2AFX | H2A histone family, member X |
| HOXA4 | homeobox A4 |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| KIAA0319L | KIAA0319-like |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LPIN2 | lipin 2 |
| MAP1S | microtubule-associated protein 1S |
| MAP4 | microtubule-associated protein 4 |
| MAPT | microtubule-associated protein tau |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MTAP | methylthioadenosine phosphorylase |
| MYO9A | myosin IXA |
| N4BP1 | NEDD4 binding protein 1 |
| NDE1 | nudE neurodevelopment protein 1 |
| OPTN | optineurin |
| PARVA | parvin, alpha |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PRDX2 | peroxiredoxin 2 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
| PRMT2IP | PRMT2 interacting protein |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| PTPRH | protein tyrosine phosphatase, receptor type, H |
| RAB33B | RAB33B, member RAS oncogene family |
| RANGAP1 | Ran GTPase activating protein 1 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats |
| RUNDC3B | RUN domain containing 3B |
| RUNX3 | runt-related transcription factor 3 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SEC24D | SEC24 family member D |
| SETDB1 | SET domain, bifurcated 1 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 |
| SIRT6 | sirtuin 6 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SMEK1 | SMEK homolog 1, suppressor of mek1 (Dictyostelium) |
| SPATA2L | spermatogenesis associated 2-like |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| STAC | SH3 and cysteine rich domain |
| STAG3 | stromal antigen 3 |
| STC1 | stanniocalcin 1 |
| STRN4 | striatin, calmodulin binding protein 4 |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
| TDRKH | tudor and KH domain containing |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TMEM80 | transmembrane protein 80 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TNIK | TRAF2 and NCK interacting kinase |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRIM2 | tripartite motif containing 2 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF224 | zinc finger protein 224 |
| ZNF318 | zinc finger protein 318 |
| ZNF512B | zinc finger protein 512B |
| ZSCAN32 | zinc finger and SCAN domain containing 32 |
| Symbol | Name |
|---|---|
| ABCA11P | ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADM | adrenomedullin |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| AVPI1 | arginine vasopressin-induced 1 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BCL2A1 | BCL2-related protein A1 |
| C9ORF91 | chromosome 9 open reading frame 91 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CBY1 | chibby homolog 1 (Drosophila) |
| CCDC68 | coiled-coil domain containing 68 |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DESI1 | desumoylating isopeptidase 1 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| EDC3 | enhancer of mRNA decapping 3 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| FAM193B | family with sequence similarity 193, member B |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| HIRA | histone cell cycle regulator |
| HSPA2 | heat shock 70kDa protein 2 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFT54 | intraflagellar transport 54 |
| IL17RA | interleukin 17 receptor A |
| INCENP | inner centromere protein antigens 135/155kDa |
| IPO8 | importin 8 |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| KCTD15 | potassium channel tetramerization domain containing 15 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MANEA | mannosidase, endo-alpha |
| METTL16 | methyltransferase like 16 |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MOB3B | MOB kinase activator 3B |
| MYLK | myosin light chain kinase |
| NCS1 | neuronal calcium sensor 1 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NID2 | nidogen 2 (osteonidogen) |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 |
| OPLAH | 5-oxoprolinase (ATP-hydrolysing) |
| OSMR | oncostatin M receptor |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PARD6A | par-6 family cell polarity regulator alpha |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLA2G15 | phospholipase A2, group XV |
| PLAC8 | placenta-specific 8 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| POLL | polymerase (DNA directed), lambda |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRMT7 | protein arginine methyltransferase 7 |
| PSENEN | presenilin enhancer gamma secretase subunit |
| ROGDI | rogdi homolog (Drosophila) |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| RUNX1-IT1 | RUNX1 intronic transcript 1 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STK16 | serine/threonine kinase 16 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TBX19 | T-box 19 |
| TGS1 | trimethylguanosine synthase 1 |
| THAP10 | THAP domain containing 10 |
| THBS3 | thrombospondin 3 |
| TMEM242 | transmembrane protein 242 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRIM16 | tripartite motif containing 16 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TUBA3C | tubulin, alpha 3c |
| ULBP2 | UL16 binding protein 2 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| YOD1 | YOD1 deubiquitinase |
| ZKSCAN4 | zinc finger with KRAB and SCAN domains 4 |
| ZNF250 | zinc finger protein 250 |
| ZNF415 | zinc finger protein 415 |
| ZNF770 | zinc finger protein 770 |
| ZXDC | ZXD family zinc finger C |