mebhydrolin-3269 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the mebhydrolin-3269 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD6 abhydrolase domain containing 6
ACVR1B activin A receptor, type IB
ADGRL1 adhesion G protein-coupled receptor L1
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APLP2 amyloid beta (A4) precursor-like protein 2
APOM apolipoprotein M
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
C1QL1 complement component 1, q subcomponent-like 1
CA5B carbonic anhydrase VB, mitochondrial
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CD82 CD82 molecule
CDC25A cell division cycle 25A
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
COPZ2 coatomer protein complex, subunit zeta 2
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa
CRIP1 cysteine-rich protein 1 (intestinal)
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DGCR2 DiGeorge syndrome critical region gene 2
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
EGFL7 EGF-like-domain, multiple 7
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAS Fas cell surface death receptor
FGF12 fibroblast growth factor 12
FKBP10 FK506 binding protein 10, 65 kDa
FLJ42627 uncharacterized LOC645644
FSCN1 fascin actin-bundling protein 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
G6PC2 glucose-6-phosphatase, catalytic, 2
GZMK granzyme K (granzyme 3; tryptase II)
HIPK2 homeodomain interacting protein kinase 2
IGFBP3 insulin-like growth factor binding protein 3
IL5RA interleukin 5 receptor, alpha
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
KAT6A K(lysine) acetyltransferase 6A
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KRT15 keratin 15, type I
LMF2 lipase maturation factor 2
LPCAT3 lysophosphatidylcholine acyltransferase 3
LRP2 low density lipoprotein receptor-related protein 2
LY86 lymphocyte antigen 86
LZTR1 leucine-zipper-like transcription regulator 1
MAGOH2P mago-nashi homolog 2, pseudogene
MARK2 MAP/microtubule affinity-regulating kinase 2
MED25 mediator complex subunit 25
MIIP migration and invasion inhibitory protein
MOCS1 molybdenum cofactor synthesis 1
MTAP methylthioadenosine phosphorylase
MUC1 mucin 1, cell surface associated
MXD4 MAX dimerization protein 4
NECAB2 N-terminal EF-hand calcium binding protein 2
NOL10 nucleolar protein 10
NR2F1 nuclear receptor subfamily 2, group F, member 1
NRF1 nuclear respiratory factor 1
NRP2 neuropilin 2
NRTN neurturin
PCDHB3 protocadherin beta 3
PDCD2 programmed cell death 2
PDCD6 programmed cell death 6
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PER1 period circadian clock 1
PLAUR plasminogen activator, urokinase receptor
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PROS1 protein S (alpha)
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RAB27B RAB27B, member RAS oncogene family
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
REC8 REC8 meiotic recombination protein
REPS1 RALBP1 associated Eps domain containing 1
RHBG Rh family, B glycoprotein (gene/pseudogene)
RHOBTB2 Rho-related BTB domain containing 2
RIMS3 regulating synaptic membrane exocytosis 3
RPL10L ribosomal protein L10-like
RUSC2 RUN and SH3 domain containing 2
SCAND2P SCAN domain containing 2 pseudogene
SIK3 SIK family kinase 3
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SLC35E2 solute carrier family 35, member E2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STMN1 stathmin 1
STON1 stonin 1
STS steroid sulfatase (microsomal), isozyme S
STX7 syntaxin 7
SWAP70 SWAP switching B-cell complex 70kDa subunit
SYMPK symplekin
SYNRG synergin, gamma
SZT2 seizure threshold 2 homolog (mouse)
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TMEM120B transmembrane protein 120B
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRD T cell receptor delta locus
TRIM36 tripartite motif containing 36
VAMP5 vesicle-associated membrane protein 5
VIPR1 vasoactive intestinal peptide receptor 1
VLDLR very low density lipoprotein receptor
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
ZFP64 ZFP64 zinc finger protein
ZNF768 zinc finger protein 768

decreased expression

Symbol Name
ACTL8 actin-like 8
ADAP2 ArfGAP with dual PH domains 2
APOLD1 apolipoprotein L domain containing 1
ARMC4 armadillo repeat containing 4
ARRB1 arrestin, beta 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BAHCC1 BAH domain and coiled-coil containing 1
C19ORF73 chromosome 19 open reading frame 73
C9ORF9 chromosome 9 open reading frame 9
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CCNO cyclin O
CHRM3 cholinergic receptor, muscarinic 3
CORO2A coronin, actin binding protein, 2A
CSF1R colony stimulating factor 1 receptor
CXORF56 chromosome X open reading frame 56
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFHD2 EF-hand domain family, member D2
EMID1 EMI domain containing 1
F2R coagulation factor II (thrombin) receptor
FAM131A family with sequence similarity 131, member A
FAM155B family with sequence similarity 155, member B
FAM189A2 family with sequence similarity 189, member A2
FAM63A family with sequence similarity 63, member A
FBRS fibrosin
FBXO22 F-box protein 22
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FER fer (fps/fes related) tyrosine kinase
FILIP1L filamin A interacting protein 1-like
FOSL1 FOS-like antigen 1
GADD45G growth arrest and DNA-damage-inducible, gamma
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GFOD1 glucose-fructose oxidoreductase domain containing 1
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GINS4 GINS complex subunit 4 (Sld5 homolog)
GPR143 G protein-coupled receptor 143
GPR27 G protein-coupled receptor 27
HIST1H3B histone cluster 1, H3b
HOXC10 homeobox C10
HYI hydroxypyruvate isomerase (putative)
IFNAR1 interferon (alpha, beta and omega) receptor 1
IQSEC2 IQ motif and Sec7 domain 2
IRAK4 interleukin-1 receptor-associated kinase 4
KCNK15 potassium channel, two pore domain subfamily K, member 15
KCTD20 potassium channel tetramerization domain containing 20
KCTD7 potassium channel tetramerization domain containing 7
KIAA0754 KIAA0754
KLK5 kallikrein-related peptidase 5
LHX1 LIM homeobox 1
LIG4 ligase IV, DNA, ATP-dependent
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LYPLA2P1 lysophospholipase II pseudogene 1
LYRM9 LYR motif containing 9
MBNL3 muscleblind-like splicing regulator 3
MBTD1 mbt domain containing 1
MED15 mediator complex subunit 15
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NHEJ1 nonhomologous end-joining factor 1
NIPAL2 NIPA-like domain containing 2
NPIPB15 nuclear pore complex interacting protein family, member B15
NRGN neurogranin (protein kinase C substrate, RC3)
OSMR oncostatin M receptor
PACS1 phosphofurin acidic cluster sorting protein 1
PDIA3 protein disulfide isomerase family A, member 3
POM121 POM121 transmembrane nucleoporin
PPT2 palmitoyl-protein thioesterase 2
RAB3D RAB3D, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF122 ring finger protein 122
RNF2 ring finger protein 2
RPL23AP32 ribosomal protein L23a pseudogene 32
SLC12A8 solute carrier family 12, member 8
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC46A3 solute carrier family 46, member 3
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SNAI2 snail family zinc finger 2
TCHH trichohyalin
TMC7 transmembrane channel-like 7
TMEM209 transmembrane protein 209
TPST2 tyrosylprotein sulfotransferase 2
TTC17 tetratricopeptide repeat domain 17
VAX2 ventral anterior homeobox 2
WDR91 WD repeat domain 91
WFDC2 WAP four-disulfide core domain 2
WLS wntless Wnt ligand secretion mediator
XK X-linked Kx blood group
ZNF211 zinc finger protein 211
ZNF446 zinc finger protein 446
ZNF652 zinc finger protein 652
ZNF675 zinc finger protein 675
ZNRD1-AS1 ZNRD1 antisense RNA 1