mebhydrolin-4211 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

196 genes differentially expressed following the mebhydrolin-4211 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOT11 acyl-CoA thioesterase 11
ACVR1B activin A receptor, type IB
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AKR1D1 aldo-keto reductase family 1, member D1
ARHGAP35 Rho GTPase activating protein 35
ATF7IP activating transcription factor 7 interacting protein
ATG10 autophagy related 10
BMP4 bone morphogenetic protein 4
C4ORF29 chromosome 4 open reading frame 29
CALB2 calbindin 2
CASP2 caspase 2, apoptosis-related cysteine peptidase
CATR1 CATR tumorigenicity conversion 1
CCIN calicin
CCNO cyclin O
CD58 CD58 molecule
CDC14B cell division cycle 14B
CEL carboxyl ester lipase
CEP164 centrosomal protein 164kDa
CLTB clathrin, light chain B
COL7A1 collagen, type VII, alpha 1
CXCR2 chemokine (C-X-C motif) receptor 2
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DENND2A DENN/MADD domain containing 2A
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DIO2 deiodinase, iodothyronine, type II
DLX2 distal-less homeobox 2
DPEP2 dipeptidase 2
DRICH1 aspartate-rich 1
DTX2 deltex 2, E3 ubiquitin ligase
EMID1 EMI domain containing 1
EML3 echinoderm microtubule associated protein like 3
EPHA1 EPH receptor A1
FAM188A family with sequence similarity 188, member A
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GABARAPL1 GABA(A) receptor-associated protein like 1
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPR75 G protein-coupled receptor 75
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene)
HABP2 hyaluronan binding protein 2
HBB hemoglobin, beta
ICA1 islet cell autoantigen 1, 69kDa
IFITM1 interferon induced transmembrane protein 1
IGFBP1 insulin-like growth factor binding protein 1
INO80D INO80 complex subunit D
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
INSIG1 insulin induced gene 1
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KRT17 keratin 17, type I
LAT2 linker for activation of T cells family, member 2
LCAT lecithin-cholesterol acyltransferase
LGALS4 lectin, galactoside-binding, soluble, 4
LIMK1 LIM domain kinase 1
MAPK11 mitogen-activated protein kinase 11
MECOM MDS1 and EVI1 complex locus
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRP2 neuropilin 2
OSBPL10 oxysterol binding protein-like 10
PCDHA5 protocadherin alpha 5
PCSK6 proprotein convertase subtilisin/kexin type 6
PDE4DIP phosphodiesterase 4D interacting protein
PHKG1 phosphorylase kinase, gamma 1 (muscle)
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PTPRR protein tyrosine phosphatase, receptor type, R
PTPRU protein tyrosine phosphatase, receptor type, U
RAB36 RAB36, member RAS oncogene family
RBFA ribosome binding factor A (putative)
RBMS3 RNA binding motif, single stranded interacting protein 3
RFPL3S RFPL3 antisense
RXRB retinoid X receptor, beta
SAMD4A sterile alpha motif domain containing 4A
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCARB1 scavenger receptor class B, member 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SFTPA2 surfactant protein A2
SLA Src-like-adaptor
SLMO1 slowmo homolog 1 (Drosophila)
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPATA2L spermatogenesis associated 2-like
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SVIL supervillin
TEX40 testis expressed 40
TFDP3 transcription factor Dp family, member 3
THSD4 thrombospondin, type I, domain containing 4
TRPM1 transient receptor potential cation channel, subfamily M, member 1
TTC30A tetratricopeptide repeat domain 30A
UPK1B uroplakin 1B
UPK2 uroplakin 2
USP53 ubiquitin specific peptidase 53
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
ZC2HC1C zinc finger, C2HC-type containing 1C
ZMIZ2 zinc finger, MIZ-type containing 2

decreased expression

Symbol Name
ACSBG2 acyl-CoA synthetase bubblegum family member 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ARHGAP22 Rho GTPase activating protein 22
ARPIN actin-related protein 2/3 complex inhibitor
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATAD5 ATPase family, AAA domain containing 5
BFSP1 beaded filament structural protein 1, filensin
C14ORF105 chromosome 14 open reading frame 105
C19ORF40 chromosome 19 open reading frame 40
C22ORF29 chromosome 22 open reading frame 29
C3ORF36 chromosome 3 open reading frame 36
C8A complement component 8, alpha polypeptide
C9ORF40 chromosome 9 open reading frame 40
CASP5 caspase 5, apoptosis-related cysteine peptidase
CASS4 Cas scaffolding protein family member 4
CBX8 chromobox homolog 8
CCNE1 cyclin E1
CEMP1 cementum protein 1
CES1 carboxylesterase 1
CIDEB cell death-inducing DFFA-like effector b
CLDN15 claudin 15
CLTCL1 clathrin, heavy chain-like 1
CNN1 calponin 1, basic, smooth muscle
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CPB1 carboxypeptidase B1 (tissue)
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DNM3 dynamin 3
DSPP dentin sialophosphoprotein
ENO3 enolase 3 (beta, muscle)
ERCC4 excision repair cross-complementation group 4
FKRP fukutin related protein
FLJ21369 uncharacterized protein FLJ21369
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GLS2 glutaminase 2 (liver, mitochondrial)
GPATCH2L G patch domain containing 2-like
GRM4 glutamate receptor, metabotropic 4
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HIST1H2AK histone cluster 1, H2ak
HOXA6 homeobox A6
ICOS inducible T-cell co-stimulator
IDI2-AS1 IDI2 antisense RNA 1
IFNA17 interferon, alpha 17
IFNA8 interferon, alpha 8
IFT140 intraflagellar transport 140
IMPG1 interphotoreceptor matrix proteoglycan 1
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KANSL3 KAT8 regulatory NSL complex subunit 3
KIAA1456 KIAA1456
KRT20 keratin 20, type I
LAX1 lymphocyte transmembrane adaptor 1
LOC157562 uncharacterized LOC157562
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LTC4S leukotriene C4 synthase
LY86 lymphocyte antigen 86
MRAS muscle RAS oncogene homolog
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPL41 mitochondrial ribosomal protein L41
MTCP1 mature T-cell proliferation 1
MTSS1L metastasis suppressor 1-like
MYO15A myosin XVA
NBEAL2 neurobeachin-like 2
NDRG4 NDRG family member 4
NOTCH4 notch 4
OTOF otoferlin
PBOV1 prostate and breast cancer overexpressed 1
PHKG2 phosphorylase kinase, gamma 2 (testis)
PLA2G1B phospholipase A2, group IB (pancreas)
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRB3 proline-rich protein BstNI subfamily 3
PRM2 protamine 2
PROL1 proline rich, lacrimal 1
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
RIBC2 RIB43A domain with coiled-coils 2
S1PR1 sphingosine-1-phosphate receptor 1
SAYSD1 SAYSVFN motif domain containing 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
TDRD1 tudor domain containing 1
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TIMP4 TIMP metallopeptidase inhibitor 4
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMEM53 transmembrane protein 53
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TUBA3C tubulin, alpha 3c
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UGT8 UDP glycosyltransferase 8
VGF VGF nerve growth factor inducible
VGLL3 vestigial-like family member 3
ZBTB22 zinc finger and BTB domain containing 22
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF480 zinc finger protein 480