| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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193 genes differentially expressed following the mecamylamine-3525 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACPP | acid phosphatase, prostate |
| ADAM22 | ADAM metallopeptidase domain 22 |
| AIM1L | absent in melanoma 1-like |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 |
| ALS2CL | ALS2 C-terminal like |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATP1A3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| B9D1 | B9 protein domain 1 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit |
| CD83 | CD83 molecule |
| CDH8 | cadherin 8, type 2 |
| COMMD4 | COMM domain containing 4 |
| CTIF | CBP80/20-dependent translation initiation factor |
| CTRL | chymotrypsin-like |
| CTSZ | cathepsin Z |
| DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
| DYM | dymeclin |
| DYSF | dysferlin |
| EML2 | echinoderm microtubule associated protein like 2 |
| EPHB2 | EPH receptor B2 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| EXTL3 | exostosin-like glycosyltransferase 3 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FYB | FYN binding protein |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GM2A | GM2 ganglioside activator |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits |
| GPR135 | G protein-coupled receptor 135 |
| GSPT1 | G1 to S phase transition 1 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IFT27 | intraflagellar transport 27 |
| IGLJ3 | immunoglobulin lambda joining 3 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| IL24 | interleukin 24 |
| IL6 | interleukin 6 |
| KCNA5 | potassium channel, voltage gated shaker related subfamily A, member 5 |
| KCNAB3 | potassium channel, voltage gated subfamily A regulatory beta subunit 3 |
| KCNJ8 | potassium channel, inwardly rectifying subfamily J, member 8 |
| KIAA0754 | KIAA0754 |
| KIAA1109 | KIAA1109 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MSMB | microseminoprotein, beta- |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NCOA2 | nuclear receptor coactivator 2 |
| NEUROD1 | neuronal differentiation 1 |
| NF2 | neurofibromin 2 (merlin) |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 |
| NLGN1 | neuroligin 1 |
| NME5 | NME/NM23 family member 5 |
| NOP16 | NOP16 nucleolar protein |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NRF1 | nuclear respiratory factor 1 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PARD6B | par-6 family cell polarity regulator beta |
| PCDHB3 | protocadherin beta 3 |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta |
| PLK3 | polo-like kinase 3 |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| PTRF | polymerase I and transcript release factor |
| RAB6B | RAB6B, member RAS oncogene family |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 |
| RPS3A | ribosomal protein S3A |
| RUFY3 | RUN and FYVE domain containing 3 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SERPINB13 | serpin peptidase inhibitor, clade B (ovalbumin), member 13 |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SNTA1 | syntrophin, alpha 1 |
| SP100 | SP100 nuclear antigen |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| STAB2 | stabilin 2 |
| SVIL | supervillin |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TEX15 | testis expressed 15 |
| TMEM19 | transmembrane protein 19 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TRD | T cell receptor delta locus |
| WDR1 | WD repeat domain 1 |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| ZEB1 | zinc finger E-box binding homeobox 1 |
| ZNF440 | zinc finger protein 440 |
| Symbol | Name |
|---|---|
| ALPK1 | alpha-kinase 1 |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| ATP6V0A4 | ATPase, H+ transporting, lysosomal V0 subunit a4 |
| BMP4 | bone morphogenetic protein 4 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| CA11 | carbonic anhydrase XI |
| CAMTA1 | calmodulin binding transcription activator 1 |
| CAPN15 | calpain 15 |
| CCDC186 | coiled-coil domain containing 186 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CD302 | CD302 molecule |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CEP170B | centrosomal protein 170B |
| CHST10 | carbohydrate sulfotransferase 10 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CORT | cortistatin |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DEAF1 | DEAF1 transcription factor |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DVL1 | dishevelled segment polarity protein 1 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| ENO2 | enolase 2 (gamma, neuronal) |
| ERCC4 | excision repair cross-complementation group 4 |
| FAAH | fatty acid amide hydrolase |
| FAM169A | family with sequence similarity 169, member A |
| FAM46C | family with sequence similarity 46, member C |
| GALK1 | galactokinase 1 |
| GCHFR | GTP cyclohydrolase I feedback regulator |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIST1H2BO | histone cluster 1, H2bo |
| HOXC8 | homeobox C8 |
| INPP1 | inositol polyphosphate-1-phosphatase |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KIAA0894 | KIAA0894 protein |
| KIF13B | kinesin family member 13B |
| KLF2 | Kruppel-like factor 2 |
| KRT8P12 | keratin 8 pseudogene 12 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LMNB2 | lamin B2 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAGEA6 | melanoma antigen family A6 |
| MBTD1 | mbt domain containing 1 |
| MGC12488 | |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| NBEAL2 | neurobeachin-like 2 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NPTX1 | neuronal pentraxin I |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| PTDSS2 | phosphatidylserine synthase 2 |
| PTK6 | protein tyrosine kinase 6 |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC16A2 | solute carrier family 16, member 2 (thyroid hormone transporter) |
| SLC35F5 | solute carrier family 35, member F5 |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| STON1 | stonin 1 |
| STX1A | syntaxin 1A (brain) |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAOK1 | TAO kinase 1 |
| TCP10 | t-complex 10 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TMEM184B | transmembrane protein 184B |
| TMEM53 | transmembrane protein 53 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TRIM25 | tripartite motif containing 25 |
| TSSC4 | tumor suppressing subtransferable candidate 4 |
| TTC30A | tetratricopeptide repeat domain 30A |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| UBQLN4 | ubiquilin 4 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) |
| XAB2 | XPA binding protein 2 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF573 | zinc finger protein 573 |
| ZNF606 | zinc finger protein 606 |
| ZNF652 | zinc finger protein 652 |
| ZNF747 | zinc finger protein 747 |
