mecamylamine-hcl Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
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Genes

637 genes differentially expressed following the mecamylamine-hcl small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
TBP TATA box binding protein 6.69516
NME8 NME/NM23 family member 8 6.6224
ZNF467 zinc finger protein 467 5.91452
MTF2 metal response element binding transcription factor 2 5.81705
NOS3 nitric oxide synthase 3 (endothelial cell) 5.74835
GSTZ1 glutathione S-transferase zeta 1 5.73062
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 5.72105
DCAF6 DDB1 and CUL4 associated factor 6 5.69473
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 5.69128
RPS4Y1 ribosomal protein S4, Y-linked 1 5.64816
CEP57 centrosomal protein 57kDa 5.63229
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 5.31146
ACAA1 acetyl-CoA acyltransferase 1 5.2856
DLG2 discs, large homolog 2 (Drosophila) 5.28034
ZNF350 zinc finger protein 350 5.2185
RBM3 RNA binding motif (RNP1, RRM) protein 3 5.14024
ZNF667 zinc finger protein 667 5.11483
RDH5 retinol dehydrogenase 5 (11-cis/9-cis) 5.08316
CASP7 caspase 7, apoptosis-related cysteine peptidase 5.07337
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 5.00465
SEC62 SEC62 homolog (S. cerevisiae) 4.97332
DDN dendrin 4.94638
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 4.93771
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 4.93727
CFAP46 cilia and flagella associated protein 46 4.90935
IL9 interleukin 9 4.82084
PIGN phosphatidylinositol glycan anchor biosynthesis, class N 4.77144
CYCS cytochrome c, somatic 4.76597
EPN2 epsin 2 4.72937
RABGGTB Rab geranylgeranyltransferase, beta subunit 4.7247
CPM carboxypeptidase M 4.72415
CDA cytidine deaminase 4.69566
CRK v-crk avian sarcoma virus CT10 oncogene homolog 4.67864
IFNAR1 interferon (alpha, beta and omega) receptor 1 4.67647
OGG1 8-oxoguanine DNA glycosylase 4.66993
ADAM9 ADAM metallopeptidase domain 9 4.66195
PRKACB protein kinase, cAMP-dependent, catalytic, beta 4.64313
EFHC1 EF-hand domain (C-terminal) containing 1 4.62092
ZNF23 zinc finger protein 23 4.59185
E2F2 E2F transcription factor 2 4.57686
WBP4 WW domain binding protein 4 4.57683
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 4.56834
NAP1L1 nucleosome assembly protein 1-like 1 4.54511
TCL1B T-cell leukemia/lymphoma 1B 4.51584
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1 4.50559
AGTPBP1 ATP/GTP binding protein 1 4.48603
KLF1 Kruppel-like factor 1 (erythroid) 4.48566
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 4.45563
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 4.44481
DIPK1A divergent protein kinase domain 1A 4.43837
IL27RA interleukin 27 receptor, alpha 4.4212
NFE2 nuclear factor, erythroid 2 4.35207
ZP2 zona pellucida glycoprotein 2 (sperm receptor) 4.34781
RETREG1 reticulophagy regulator 1 4.30938
LEMD3 LEM domain containing 3 4.30907
SLITRK2 SLIT and NTRK-like family, member 2 4.27335
ZNF432 zinc finger protein 432 4.27136
VAMP4 vesicle-associated membrane protein 4 4.24555
JPH3 junctophilin 3 4.19195
ACVR1B activin A receptor, type IB 4.18831
PRPF38B pre-mRNA processing factor 38B 4.18168
TMEM80 transmembrane protein 80 4.1638
PTDSS1 phosphatidylserine synthase 1 4.15639
UBQLN2 ubiquilin 2 4.14818
EPHA5 EPH receptor A5 4.1391
GGCT gamma-glutamylcyclotransferase 4.13516
AMPD2 adenosine monophosphate deaminase 2 4.11143
TM2D3 TM2 domain containing 3 4.1014
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 4.09446
RAP1B RAP1B, member of RAS oncogene family 4.09256
RAP2C RAP2C, member of RAS oncogene family 4.08765
DMXL1 Dmx-like 1 4.08115
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 4.0779
GP2 glycoprotein 2 (zymogen granule membrane) 4.07786
ERC1 ELKS/RAB6-interacting/CAST family member 1 4.07352
PDZD2 PDZ domain containing 2 4.07253
RBMX2 RNA binding motif protein, X-linked 2 4.06988
FKBP1A FK506 binding protein 1A, 12kDa 4.05706
LINC01963 long intergenic non-protein coding RNA 1963 4.0457
EGR1 early growth response 1 4.03987
SNAP25 synaptosomal-associated protein, 25kDa 4.03646
APMAP adipocyte plasma membrane associated protein 4.03524
CYB561 cytochrome b561 4.02124
NME6 NME/NM23 nucleoside diphosphate kinase 6 4.00729
UQCRB ubiquinol-cytochrome c reductase binding protein 4.00395
PDIA5 protein disulfide isomerase family A, member 5 3.99765
ATG101 autophagy related 101 3.99141
TARBP1 TAR (HIV-1) RNA binding protein 1 3.98904
CRYM crystallin, mu 3.98709
BTBD3 BTB (POZ) domain containing 3 3.9788
SST somatostatin 3.97797
MRE11 MRE11 homolog, double strand break repair nuclease 3.97469
VAX2 ventral anterior homeobox 2 3.96413
KCTD12 potassium channel tetramerization domain containing 12 3.93912
ZNF7 zinc finger protein 7 3.9386
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 3.93703
KLK14 kallikrein-related peptidase 14 3.93551
DUSP13 dual specificity phosphatase 13 3.92734
CYTIP cytohesin 1 interacting protein 3.91621
SGPP1 sphingosine-1-phosphate phosphatase 1 3.91593
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 3.91214
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 3.89756
EML1 echinoderm microtubule associated protein like 1 3.88423
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 3.88324
FGF9 fibroblast growth factor 9 3.865
CALB1 calbindin 1, 28kDa 3.84137
ARPP21 cAMP-regulated phosphoprotein, 21kDa 3.82808
GPR6 G protein-coupled receptor 6 3.82584
YEATS2 YEATS domain containing 2 3.80814
ZNF215 zinc finger protein 215 3.79921
SUB1 SUB1 homolog (S. cerevisiae) 3.79823
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae) 3.78948
REXO5 RNA exonuclease 5 3.77771
JPH2 junctophilin 2 3.77192
RPH3AL rabphilin 3A-like (without C2 domains) 3.7601
CHGA chromogranin A 3.73185
TMSB10 thymosin beta 10 3.72953
CETP cholesteryl ester transfer protein, plasma 3.72759
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 3.72342
ZNF135 zinc finger protein 135 3.71736
ANO3 anoctamin 3 3.717
MYT1 myelin transcription factor 1 3.71603
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 3.70654
MYT1L myelin transcription factor 1-like 3.70609
RPS28 ribosomal protein S28 3.69426
MAN2B1 mannosidase, alpha, class 2B, member 1 3.69014
GALNT8 polypeptide N-acetylgalactosaminyltransferase 8 3.687
FOXG1 forkhead box G1 3.68586
ZNF556 zinc finger protein 556 3.68094
ANPEP alanyl (membrane) aminopeptidase 3.67584
PRSS21 protease, serine, 21 (testisin) 3.66798
MFAP5 microfibrillar associated protein 5 3.66635
ZNF345 zinc finger protein 345 3.65682
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 3.65152
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 3.6459
LIAS lipoic acid synthetase 3.64493
COL9A1 collagen, type IX, alpha 1 3.64393
MPO myeloperoxidase 3.62789
STXBP6 syntaxin binding protein 6 (amisyn) 3.62478
TICAM1 toll-like receptor adaptor molecule 1 3.62155
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 3.61529
MEOX2 mesenchyme homeobox 2 3.61341
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa 3.60752
BAALC brain and acute leukemia, cytoplasmic 3.60255
CKAP4 cytoskeleton-associated protein 4 3.59886
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 3.59145
NCDN neurochondrin 3.58641
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 3.58241
LAMA2 laminin, alpha 2 3.55455
CCT2 chaperonin containing TCP1, subunit 2 (beta) 3.55181
CYFIP2 cytoplasmic FMR1 interacting protein 2 3.54696
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 3.54183
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 3.54095
FAM131B family with sequence similarity 131, member B 3.53627
TEK TEK tyrosine kinase, endothelial 3.53109
RHOA ras homolog family member A 3.53009
ZKSCAN7 zinc finger with KRAB and SCAN domains 7 3.52561
DMXL2 Dmx-like 2 3.51173
LIMS3 LIM and senescent cell antigen-like domains 3 3.50447
IL1R2 interleukin 1 receptor, type II 3.5028
SRCAP Snf2-related CREBBP activator protein 3.50197
PLCL2 phospholipase C-like 2 3.49988
MTERF3 mitochondrial transcription termination factor 3 3.49648
BSN bassoon presynaptic cytomatrix protein 3.49643
MYOZ2 myozenin 2 3.48281
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 3.4775
CACNG3 calcium channel, voltage-dependent, gamma subunit 3 3.47491
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 3.46673
ZNF14 zinc finger protein 14 3.4644
PLA2G15 phospholipase A2, group XV 3.46006
ALOX15B arachidonate 15-lipoxygenase, type B 3.45808
EMX1 empty spiracles homeobox 1 3.45659
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 3.45611
GCG glucagon 3.4429
KLHL41 kelch-like family member 41 3.44023
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene 3.43981
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 3.43908
PTH parathyroid hormone 3.43831
YIF1B Yip1 interacting factor homolog B (S. cerevisiae) 3.43749
PCP4 Purkinje cell protein 4 3.43253
HBE1 hemoglobin, epsilon 1 3.43197
ZNF804A zinc finger protein 804A 3.43024
MCTP2 multiple C2 domains, transmembrane 2 3.42623
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 3.42137
ADGRG3 adhesion G protein-coupled receptor G3 3.40776
CLOCK clock circadian regulator 3.40614
ITM2C integral membrane protein 2C 3.40251
RIPK2 receptor-interacting serine-threonine kinase 2 3.39578
MTERF1 mitochondrial transcription termination factor 1 3.39318
COPS5 COP9 signalosome subunit 5 3.37856
RNF41 ring finger protein 41, E3 ubiquitin protein ligase 3.37797
IFITM1 interferon induced transmembrane protein 1 3.36655
EIF4E2 eukaryotic translation initiation factor 4E family member 2 3.36386
RNF115 ring finger protein 115 3.36348
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C 3.36026
TRIM5 tripartite motif containing 5 3.35869
TSPAN13 tetraspanin 13 3.35425
TMEM260 transmembrane protein 260 3.34579
TFEC transcription factor EC 3.33251
RAP1GAP2 RAP1 GTPase activating protein 2 3.32545
EBF2 early B-cell factor 2 3.32476
DPY19L1P1 DPY19L1 pseudogene 1 3.32344
ADD3 adducin 3 (gamma) 3.32253
CDK17 cyclin-dependent kinase 17 3.31908
ZNF302 zinc finger protein 302 3.31801
FBXO3 F-box protein 3 3.31562
HDAC4 histone deacetylase 4 3.31034
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 3.30952
TMEM11 transmembrane protein 11 3.30638
FAIM Fas apoptotic inhibitory molecule 3.29914
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 3.29815
UBE2D2 ubiquitin-conjugating enzyme E2D 2 3.29585
MID1IP1 MID1 interacting protein 1 3.29386
RIMBP2 RIMS binding protein 2 3.28483
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 3.27263
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 3.27068
AKAP8 A kinase (PRKA) anchor protein 8 3.26641
CRBN cereblon 3.26591
RCVRN recoverin 3.26522
AKTIP AKT interacting protein 3.26157
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa 3.26066
NPTX1 neuronal pentraxin I 3.25581
ADGRL3 adhesion G protein-coupled receptor L3 3.25552
GAS7 growth arrest-specific 7 3.25279
HYAL1 hyaluronoglucosaminidase 1 3.24911
PDHX pyruvate dehydrogenase complex, component X 3.24702
AMPD1 adenosine monophosphate deaminase 1 3.24323
WDR7 WD repeat domain 7 3.23988
MYH4 myosin, heavy chain 4, skeletal muscle 3.23606
FFAR2 free fatty acid receptor 2 3.22555
CTSZ cathepsin Z 3.22413
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4 3.22192
PINK1 PTEN induced putative kinase 1 3.21772
PLSCR3 phospholipid scramblase 3 3.2089
TAGLN3 transgelin 3 3.20736
ZNF136 zinc finger protein 136 3.2063
FKBP9 FK506 binding protein 9, 63 kDa 3.20422
ULK2 unc-51 like autophagy activating kinase 2 3.20388
ITPKA inositol-trisphosphate 3-kinase A 3.19507
BZW1 basic leucine zipper and W2 domains 1 3.19421
GPR173 G protein-coupled receptor 173 3.1933
GCA grancalcin, EF-hand calcium binding protein 3.19247
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 3.19233
FOXI1 forkhead box I1 3.19175
CHMP3 charged multivesicular body protein 3 3.18764
EIF5B eukaryotic translation initiation factor 5B 3.18753
KDM5D lysine (K)-specific demethylase 5D 3.18232
CDH16 cadherin 16, KSP-cadherin 3.1763
LSM1 LSM1, U6 small nuclear RNA associated 3.17388
LETMD1 LETM1 domain containing 1 3.17261
CCNI cyclin I 3.17182
PRTN3 proteinase 3 3.17032
BARX1 BARX homeobox 1 3.16938
ZDHHC17 zinc finger, DHHC-type containing 17 3.16795
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 3.16684
YTHDC2 YTH domain containing 2 3.16585
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 3.1653
SYP synaptophysin 3.16123
UFC1 ubiquitin-fold modifier conjugating enzyme 1 3.14761
NLRP1 NLR family, pyrin domain containing 1 3.14249
SLC26A2 solute carrier family 26 (anion exchanger), member 2 3.14067
TESK1 testis-specific kinase 1 3.14025
GRB14 growth factor receptor-bound protein 14 3.14017
ATP5PB ATP synthase peripheral stalk-membrane subunit b 3.13631
FAR2 fatty acyl CoA reductase 2 3.13262
EFNA2 ephrin-A2 3.12716
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) 3.12573
TOGARAM1 TOG array regulator of axonemal microtubules 1 3.12478
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 3.11751
LTB lymphotoxin beta (TNF superfamily, member 3) 3.11339
MMP10 matrix metallopeptidase 10 3.11154
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 3.10666
BMP5 bone morphogenetic protein 5 3.10594
SP110 SP110 nuclear body protein 3.10584
ART3 ADP-ribosyltransferase 3 3.09781
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 3.09749
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 3.09728
PPCS phosphopantothenoylcysteine synthetase 3.0958
CD244 CD244 molecule, natural killer cell receptor 2B4 3.09478
MAPRE3 microtubule-associated protein, RP/EB family, member 3 3.09274
TWF1 twinfilin actin binding protein 1 3.09101
FBN2 fibrillin 2 3.09
JTB jumping translocation breakpoint 3.07922
ANAPC15 anaphase promoting complex subunit 15 3.07912
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 3.07881
NAIP NLR family, apoptosis inhibitory protein 3.07708
ELMO1 engulfment and cell motility 1 3.07645
ARF4 ADP-ribosylation factor 4 3.06157
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 3.06052
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 3.05189
GFRA3 GDNF family receptor alpha 3 3.05126
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2 3.04753
CCS copper chaperone for superoxide dismutase 3.04576
SP140 SP140 nuclear body protein 3.03914
GOLPH3 golgi phosphoprotein 3 (coat-protein) 3.03081
TCIM transcriptional and immune response regulator 3.03007
SDC4 syndecan 4 3.0281
VPS13B vacuolar protein sorting 13 homolog B (yeast) 3.0257
SNU13 small nuclear ribonucleoprotein 13 3.02471
ATP4B ATPase, H+/K+ exchanging, beta polypeptide 3.02137
EDRF1 erythroid differentiation regulatory factor 1 3.02069
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa 3.01806
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 3.0143
CRHBP corticotropin releasing hormone binding protein 3.01426
ADGRB3 adhesion G protein-coupled receptor B3 3.01377
ZNF668 zinc finger protein 668 3.01335
SCAF11 SR-related CTD-associated factor 11 3.01304
ZNF266 zinc finger protein 266 3.01156
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 3.00212
C11ORF21 chromosome 11 open reading frame 21 3.001
NSD3 nuclear receptor binding SET domain protein 3 3.00063

decreased expression

Symbol Name Standardized Value
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -7.14406
RBKS ribokinase -6.93314
STAP2 signal transducing adaptor family member 2 -6.78795
UNC5C unc-5 homolog C (C. elegans) -6.14987
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 -6.0663
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) -5.87213
NELFE negative elongation factor complex member E -5.7065
SLC45A2 solute carrier family 45, member 2 -5.3583
CES1 carboxylesterase 1 -5.28275
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 -5.27759
CLCN7 chloride channel, voltage-sensitive 7 -5.27481
SUMO4 small ubiquitin-like modifier 4 -5.22505
MAPK13 mitogen-activated protein kinase 13 -5.20667
YME1L1 YME1-like 1 ATPase -5.14966
EREG epiregulin -5.13253
PER3 period circadian clock 3 -5.1296
PALB2 partner and localizer of BRCA2 -5.0786
FMO2 flavin containing monooxygenase 2 (non-functional) -5.05914
FSHR follicle stimulating hormone receptor -4.98127
HLA-DOA major histocompatibility complex, class II, DO alpha -4.963
HK1 hexokinase 1 -4.93607
RNF43 ring finger protein 43 -4.92056
PCYT2 phosphate cytidylyltransferase 2, ethanolamine -4.80038
BCL7B B-cell CLL/lymphoma 7B -4.79076
PPL periplakin -4.78685
PCCA propionyl CoA carboxylase, alpha polypeptide -4.77121
MUTYH mutY homolog -4.75941
CSNK1A1 casein kinase 1, alpha 1 -4.75773
CUL9 cullin 9 -4.73345
CDK18 cyclin-dependent kinase 18 -4.71661
CHMP6 charged multivesicular body protein 6 -4.68847
CX3CR1 chemokine (C-X3-C motif) receptor 1 -4.67787
GTF2IRD1 GTF2I repeat domain containing 1 -4.65844
IL21R interleukin 21 receptor -4.58116
TULP4 tubby like protein 4 -4.57695
RRH retinal pigment epithelium-derived rhodopsin homolog -4.54984
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein -4.52756
PMEL premelanosome protein -4.50929
CCDC7 coiled-coil domain containing 7 -4.50029
TDRD7 tudor domain containing 7 -4.49961
STIMATE STIM activating enhancer -4.48389
SLCO1A2 solute carrier organic anion transporter family, member 1A2 -4.48106
RGSL1 regulator of G-protein signaling like 1 -4.47501
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide -4.47309
ALS2CL ALS2 C-terminal like -4.45616
LAPTM5 lysosomal protein transmembrane 5 -4.4407
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -4.43555
CDKN2A cyclin-dependent kinase inhibitor 2A -4.42686
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20 -4.4173
NR1I2 nuclear receptor subfamily 1, group I, member 2 -4.4076
ANKRD6 ankyrin repeat domain 6 -4.39946
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic) -4.39497
EPHB2 EPH receptor B2 -4.39369
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) -4.38554
ADAM5 ADAM metallopeptidase domain 5 (pseudogene) -4.38258
HLA-DMA major histocompatibility complex, class II, DM alpha -4.35125
BCL2A1 BCL2-related protein A1 -4.34062
HOXA10 homeobox A10 -4.33691
HGS hepatocyte growth factor-regulated tyrosine kinase substrate -4.30133
VSIG10 V-set and immunoglobulin domain containing 10 -4.28464
ZC3H13 zinc finger CCCH-type containing 13 -4.27574
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -4.25543
CCDC85C coiled-coil domain containing 85C -4.23562
TGM5 transglutaminase 5 -4.2323
CMTR1 cap methyltransferase 1 -4.22771
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1 -4.22011
AGMAT agmatine ureohydrolase (agmatinase) -4.20083
ALK anaplastic lymphoma receptor tyrosine kinase -4.19592
CD80 CD80 molecule -4.18907
LAT2 linker for activation of T cells family, member 2 -4.17301
TFEB transcription factor EB -4.15992
DLG5 discs, large homolog 5 (Drosophila) -4.13883
CSK c-src tyrosine kinase -4.13719
KCNK12 potassium channel, two pore domain subfamily K, member 12 -4.10834
NOX1 NADPH oxidase 1 -4.10147
NTS neurotensin -4.0997
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) -4.09168
ACAT2 acetyl-CoA acetyltransferase 2 -4.07627
ZNF785 zinc finger protein 785 -4.07032
CTF1 cardiotrophin 1 -4.04548
RHEBP1 Ras-homolog enriched in brain pseudogene 1 -4.03326
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae) -4.01927
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7 -4.01418
PIWIL1 piwi-like RNA-mediated gene silencing 1 -4.00907
ADAP1 ArfGAP with dual PH domains 1 -3.99524
CAMSAP1 calmodulin regulated spectrin-associated protein 1 -3.99319
HAS2 hyaluronan synthase 2 -3.99237
CHI3L2 chitinase 3-like 2 -3.98096
RRAGD Ras-related GTP binding D -3.98066
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) -3.97879
DNAAF5 dynein, axonemal, assembly factor 5 -3.96942
GTF2I general transcription factor IIi -3.96893
DTNB dystrobrevin, beta -3.96767
FBXO22 F-box protein 22 -3.96443
APH1B APH1B gamma secretase subunit -3.96238
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa -3.95958
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1 -3.94993
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 -3.94059
GARRE1 granule associated Rac and RHOG effector 1 -3.93528
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal) -3.91784
WAC WW domain containing adaptor with coiled-coil -3.9177
IRAG2 inositol 1,4,5-triphosphate receptor associated 2 -3.89824
CXCR6 chemokine (C-X-C motif) receptor 6 -3.87532
CYLC2 cylicin, basic protein of sperm head cytoskeleton 2 -3.8682
MST1R macrophage stimulating 1 receptor -3.86388
FUT2 fucosyltransferase 2 (secretor status included) -3.84601
MAPK14 mitogen-activated protein kinase 14 -3.82585
ZNF318 zinc finger protein 318 -3.82569
EVPL envoplakin -3.79145
ULBP1 UL16 binding protein 1 -3.79104
GPR157 G protein-coupled receptor 157 -3.78936
EDAR ectodysplasin A receptor -3.78786
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 -3.78063
COLEC10 collectin sub-family member 10 (C-type lectin) -3.77742
NSUN5 NOP2/Sun domain family, member 5 -3.75822
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -3.74908
NPEPL1 aminopeptidase-like 1 -3.74274
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta) -3.7421
MROH9 maestro heat-like repeat family member 9 -3.74122
FRK fyn-related Src family tyrosine kinase -3.73959
MFSD6 major facilitator superfamily domain containing 6 -3.73876
MMRN1 multimerin 1 -3.72885
CDK11A cyclin-dependent kinase 11A -3.71144
FN3KRP fructosamine 3 kinase related protein -3.71074
PARP3 poly (ADP-ribose) polymerase family, member 3 -3.70685
BDNF brain-derived neurotrophic factor -3.70649
APOC2 apolipoprotein C-II -3.70478
PNPO pyridoxamine 5'-phosphate oxidase -3.70277
IL21 interleukin 21 -3.69383
KIFC1 kinesin family member C1 -3.69294
NRSN2 neurensin 2 -3.67904
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) -3.67745
NCAPG2 non-SMC condensin II complex, subunit G2 -3.66336
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 -3.65895
EPHX3 epoxide hydrolase 3 -3.63967
CCNB1 cyclin B1 -3.62555
NFX1 nuclear transcription factor, X-box binding 1 -3.6159
IDE insulin-degrading enzyme -3.61382
APOA2 apolipoprotein A-II -3.6111
ATP10B ATPase, class V, type 10B -3.60805
FAF1 Fas (TNFRSF6) associated factor 1 -3.60266
STK11 serine/threonine kinase 11 -3.60019
HSPA14 heat shock 70kDa protein 14 -3.58737
MNX1 motor neuron and pancreas homeobox 1 -3.58531
SCUBE2 signal peptide, CUB domain, EGF-like 2 -3.58243
HTN3 histatin 3 -3.57771
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog -3.57376
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 -3.57032
STX17 syntaxin 17 -3.56797
PFKL phosphofructokinase, liver -3.56671
PEX10 peroxisomal biogenesis factor 10 -3.54462
SPRING1 SREBF pathway regulator in golgi 1 -3.54441
OASL 2'-5'-oligoadenylate synthetase-like -3.54374
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) -3.53936
MBD5 methyl-CpG binding domain protein 5 -3.53273
SH3BP2 SH3-domain binding protein 2 -3.51572
FERMT1 fermitin family member 1 -3.51235
MSRB2 methionine sulfoxide reductase B2 -3.49993
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 -3.49689
PIM1 Pim-1 proto-oncogene, serine/threonine kinase -3.49231
EPN3 epsin 3 -3.48651
PLA1A phospholipase A1 member A -3.47638
TG thyroglobulin -3.47629
HEXA hexosaminidase A (alpha polypeptide) -3.47284
GTPBP4 GTP binding protein 4 -3.47053
SZRD1 SUZ RNA binding domain containing 1 -3.46872
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha -3.46756
VAMP3 vesicle-associated membrane protein 3 -3.46471
BRAF B-Raf proto-oncogene, serine/threonine kinase -3.45537
AKR1C1 aldo-keto reductase family 1, member C1 -3.45266
RASA3 RAS p21 protein activator 3 -3.45073
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) -3.44851
SLC16A6 solute carrier family 16, member 6 -3.44168
HR hair growth associated -3.42957
RALA v-ral simian leukemia viral oncogene homolog A (ras related) -3.42804
ZNF117 zinc finger protein 117 -3.41952
ASCC1 activating signal cointegrator 1 complex subunit 1 -3.41856
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 -3.41822
SLAMF1 signaling lymphocytic activation molecule family member 1 -3.40576
ZNF750 zinc finger protein 750 -3.40429
DBP D site of albumin promoter (albumin D-box) binding protein -3.39771
KPNA3 karyopherin alpha 3 (importin alpha 4) -3.38949
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 -3.38582
CACNB2 calcium channel, voltage-dependent, beta 2 subunit -3.38349
ARHGAP32 Rho GTPase activating protein 32 -3.37739
IKZF4 IKAROS family zinc finger 4 (Eos) -3.37643
CARHSP1 calcium regulated heat stable protein 1, 24kDa -3.37535
IRX5 iroquois homeobox 5 -3.37501
STAG3 stromal antigen 3 -3.37404
FAM184A family with sequence similarity 184, member A -3.37199
MTMR10 myotubularin related protein 10 -3.36936
MYH7B myosin, heavy chain 7B, cardiac muscle, beta -3.36899
TBX4 T-box 4 -3.36382
PARD6A par-6 family cell polarity regulator alpha -3.3618
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog -3.35957
TAS2R4 taste receptor, type 2, member 4 -3.35933
SMIM14 small integral membrane protein 14 -3.35891
PRELP proline/arginine-rich end leucine-rich repeat protein -3.34976
SH2D1A SH2 domain containing 1A -3.34574
TPT1 tumor protein, translationally-controlled 1 -3.34239
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 -3.34075
RNPEP arginyl aminopeptidase (aminopeptidase B) -3.33701
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) -3.33641
ARSL arylsulfatase L -3.33546
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 -3.33351
LGALS9 lectin, galactoside-binding, soluble, 9 -3.33198
SURF1 surfeit 1 -3.32953
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 -3.32909
SAP30BP SAP30 binding protein -3.32435
GP1BA glycoprotein Ib (platelet), alpha polypeptide -3.32132
CLCN1 chloride channel, voltage-sensitive 1 -3.32024
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -3.31632
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3 -3.31509
CROT carnitine O-octanoyltransferase -3.31383
TSPAN14 tetraspanin 14 -3.31018
JPT2 Jupiter microtubule associated homolog 2 -3.30843
TBCC tubulin folding cofactor C -3.308
ABHD6 abhydrolase domain containing 6 -3.30612
TAOK1 TAO kinase 1 -3.30048
RBM19 RNA binding motif protein 19 -3.2999
COLGALT2 collagen beta(1-O)galactosyltransferase 2 -3.29258
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 -3.28799
PRKCH protein kinase C, eta -3.28747
SOX2 SRY (sex determining region Y)-box 2 -3.2874
KDM3B lysine (K)-specific demethylase 3B -3.28253
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) -3.28127
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 -3.27137
AMOT angiomotin -3.26728
TBL3 transducin (beta)-like 3 -3.26174
RPA3 replication protein A3, 14kDa -3.26151
LSAMP limbic system-associated membrane protein -3.25994
SH3GLB2 SH3-domain GRB2-like endophilin B2 -3.25271
EPB41L5 erythrocyte membrane protein band 4.1 like 5 -3.25063
RNF208 ring finger protein 208 -3.23584
TPP2 tripeptidyl peptidase II -3.23501
TMEM63A transmembrane protein 63A -3.23387
RCOR3 REST corepressor 3 -3.22592
FGF21 fibroblast growth factor 21 -3.22472
FAM50B family with sequence similarity 50, member B -3.21481
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit -3.21469
TUBA8 tubulin, alpha 8 -3.21291
CYTH3 cytohesin 3 -3.20822
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) -3.20524
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -3.20347
CYBRD1 cytochrome b reductase 1 -3.20071
RAB38 RAB38, member RAS oncogene family -3.19837
FMO4 flavin containing monooxygenase 4 -3.19613
MR1 major histocompatibility complex, class I-related -3.19599
SDAD1 SDA1 domain containing 1 -3.19543
TJP3 tight junction protein 3 -3.19499
CDH2 cadherin 2, type 1, N-cadherin (neuronal) -3.19439
PMS2P5 postmeiotic segregation increased 2 pseudogene 5 -3.19234
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide -3.19125
FBXW4 F-box and WD repeat domain containing 4 -3.18889
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -3.1878
PARD3 par-3 family cell polarity regulator -3.1875
DTX2 deltex 2, E3 ubiquitin ligase -3.18443
MOBP myelin-associated oligodendrocyte basic protein -3.18245
LIN28A lin-28 homolog A (C. elegans) -3.18238
RGS6 regulator of G-protein signaling 6 -3.18066
MLANA melan-A -3.17841
CSNK1D casein kinase 1, delta -3.17174
QRICH1 glutamine-rich 1 -3.17028
FOS FBJ murine osteosarcoma viral oncogene homolog -3.16488
ADRA1D adrenoceptor alpha 1D -3.16419
RNF128 ring finger protein 128, E3 ubiquitin protein ligase -3.16105
RIPK4 receptor-interacting serine-threonine kinase 4 -3.15908
XPO4 exportin 4 -3.15862
ANKHD1 ankyrin repeat and KH domain containing 1 -3.15779
PLXNA1 plexin A1 -3.15712
COL10A1 collagen, type X, alpha 1 -3.15688
SYTL2 synaptotagmin-like 2 -3.14774
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 -3.1453
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 -3.14194
NMBR neuromedin B receptor -3.13952
TOP3B topoisomerase (DNA) III beta -3.13565
FRS3 fibroblast growth factor receptor substrate 3 -3.13129
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon -3.12721
BHLHE41 basic helix-loop-helix family, member e41 -3.12657
E4F1 E4F transcription factor 1 -3.1254
PCDHGA10 protocadherin gamma subfamily A, 10 -3.12259
STAT5B signal transducer and activator of transcription 5B -3.12185
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative) -3.11941
FBXO42 F-box protein 42 -3.11838
THAP11 THAP domain containing 11 -3.11688
TYR tyrosinase -3.11589
FUZ fuzzy planar cell polarity protein -3.11557
C1ORF159 chromosome 1 open reading frame 159 -3.1155
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 -3.11326
TRIM32 tripartite motif containing 32 -3.10473
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 -3.10226
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A -3.08788
LRRC17 leucine rich repeat containing 17 -3.08639
HOOK2 hook microtubule-tethering protein 2 -3.08399
POLG polymerase (DNA directed), gamma -3.08009
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 -3.07867
COL6A3 collagen, type VI, alpha 3 -3.07858
PHF11 PHD finger protein 11 -3.07772
CYFIP1 cytoplasmic FMR1 interacting protein 1 -3.07562
TCTN1 tectonic family member 1 -3.07136
RMDN3 regulator of microtubule dynamics 3 -3.06793
CRTAC1 cartilage acidic protein 1 -3.06749
MNMIP1 manchette microtubule inner protein 1 -3.06551
IER5 immediate early response 5 -3.06542
TLE6 transducin-like enhancer of split 6 -3.06266
FABP6 fatty acid binding protein 6, ileal -3.06238
EBI3 Epstein-Barr virus induced 3 -3.0613
SLC19A1 solute carrier family 19 (folate transporter), member 1 -3.06062
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 -3.06037
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 -3.04914
YAP1 Yes-associated protein 1 -3.0479
SEPHS1 selenophosphate synthetase 1 -3.04422
POR P450 (cytochrome) oxidoreductase -3.03328
NUP188 nucleoporin 188kDa -3.03305
AVPR1B arginine vasopressin receptor 1B -3.0326
SFT2D2 SFT2 domain containing 2 -3.03096
ANKRD26 ankyrin repeat domain 26 -3.0272
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 -3.0205
DCT dopachrome tautomerase -3.02027
GRK3 G protein-coupled receptor kinase 3 -3.01361
CCL25 chemokine (C-C motif) ligand 25 -3.01231
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal -3.01035
NMB neuromedin B -3.00911
OXTR oxytocin receptor -3.00439
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 -3.00365
PIGR polymeric immunoglobulin receptor -3.00233