mechanical Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

253 genes co-occuring with the biological term mechanical in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACAN aggrecan
ACE angiotensin I converting enzyme
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTN1 actinin, alpha 1
ADORA2B adenosine A2b receptor
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface
ADRBK1 adrenergic, beta, receptor kinase 1
AGER advanced glycosylation end product-specific receptor
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AGTR1 angiotensin II receptor, type 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALCAM activated leukocyte cell adhesion molecule
ALPL alkaline phosphatase, liver/bone/kidney
ANGPTL2 angiopoietin-like 2
APLN apelin
APP amyloid beta (A4) precursor protein
ARRB2 arrestin, beta 2
ATF3 activating transcription factor 3
ATOX1 antioxidant 1 copper chaperone
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATR ATR serine/threonine kinase
AURKB aurora kinase B
BCAR1 breast cancer anti-estrogen resistance 1
BCHE butyrylcholinesterase
BDKRB2 bradykinin receptor B2
BECN1 beclin 1, autophagy related
BGLAP bone gamma-carboxyglutamate (gla) protein
BMP2 bone morphogenetic protein 2
BMP7 bone morphogenetic protein 7
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CCL2 chemokine (C-C motif) ligand 2
CCL7 chemokine (C-C motif) ligand 7
CD47 CD47 molecule
CDH5 cadherin 5, type 2 (vascular endothelium)
CFL1 cofilin 1 (non-muscle)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CMA1 chymase 1, mast cell
COL17A1 collagen, type XVII, alpha 1
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COL2A1 collagen, type II, alpha 1
COL3A1 collagen, type III, alpha 1
COL5A1 collagen, type V, alpha 1
COL9A2 collagen, type IX, alpha 2
COMP cartilage oligomeric matrix protein
CRP C-reactive protein, pentraxin-related
CRYGD crystallin, gamma D
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTGF connective tissue growth factor
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSB cathepsin B
CTSL cathepsin L
CUL5 cullin 5
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL8 chemokine (C-X-C motif) ligand 8
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
CYR61 cysteine-rich, angiogenic inducer, 61
DCN decorin
DDR2 discoidin domain receptor tyrosine kinase 2
DEFA5 defensin, alpha 5, Paneth cell-specific
DES desmin
DMD dystrophin
DSG1 desmoglein 1
DYSF dysferlin
EDN1 endothelin 1
EFNA1 ephrin-A1
EGFR epidermal growth factor receptor
EIF2A eukaryotic translation initiation factor 2A, 65kDa
ELAVL1 ELAV like RNA binding protein 1
ELN elastin
EPB41 erythrocyte membrane protein band 4.1
EPHA2 EPH receptor A2
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FABP3 fatty acid binding protein 3, muscle and heart
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FGF16 fibroblast growth factor 16
FGF18 fibroblast growth factor 18
FGFR2 fibroblast growth factor receptor 2
FGG fibrinogen gamma chain
FHL2 four and a half LIM domains 2
FHL3 four and a half LIM domains 3
FLNA filamin A, alpha
FN1 fibronectin 1
FNDC1 fibronectin type III domain containing 1
FOXO3 forkhead box O3
FRS2 fibroblast growth factor receptor substrate 2
FURIN furin (paired basic amino acid cleaving enzyme)
FYN FYN proto-oncogene, Src family tyrosine kinase
GJA1 gap junction protein, alpha 1, 43kDa
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GSTP1 glutathione S-transferase pi 1
HMGB1 high mobility group box 1
HMOX1 heme oxygenase 1
HRAS Harvey rat sarcoma viral oncogene homolog
IAPP islet amyloid polypeptide
ICAM1 intercellular adhesion molecule 1
IER3 immediate early response 3
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IL13 interleukin 13
IL1B interleukin 1, beta
IL32 interleukin 32
IL4 interleukin 4
IL6 interleukin 6
IL6R interleukin 6 receptor
ILK integrin-linked kinase
ITGA1 integrin, alpha 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGA7 integrin, alpha 7
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB5 integrin, beta 5
ITGB7 integrin, beta 7
IVL involucrin
JUN jun proto-oncogene
JUP junction plakoglobin
KCNK4 potassium channel, two pore domain subfamily K, member 4
KDR kinase insert domain receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLK7 kallikrein-related peptidase 7
KRT14 keratin 14, type I
KRT16 keratin 16, type I
KRT18 keratin 18, type I
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
LAMA3 laminin, alpha 3
LEP leptin
LEPR leptin receptor
LMNA lamin A/C
LPP LIM domain containing preferred translocation partner in lipoma
LRP5 low density lipoprotein receptor-related protein 5
LTBP1 latent transforming growth factor beta binding protein 1
MAP2K6 mitogen-activated protein kinase kinase 6
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MAPT microtubule-associated protein tau
MET MET proto-oncogene, receptor tyrosine kinase
MIR137 microRNA 137
MIR146A microRNA 146a
MIR155 microRNA 155
MMP1 matrix metallopeptidase 1
MMP13 matrix metallopeptidase 13
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYH10 myosin, heavy chain 10, non-muscle
MYH9 myosin, heavy chain 9, non-muscle
MYLK myosin light chain kinase
MYO1A myosin IA
NAMPT nicotinamide phosphoribosyltransferase
NGF nerve growth factor (beta polypeptide)
NOS3 nitric oxide synthase 3 (endothelial cell)
NPPB natriuretic peptide B
NRG1 neuregulin 1
NT5E 5'-nucleotidase, ecto (CD73)
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PALLD palladin, cytoskeletal associated protein
PAWR PRKC, apoptosis, WT1, regulator
PIEZO2 piezo-type mechanosensitive ion channel component 2
PIGF phosphatidylinositol glycan anchor biosynthesis, class F
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLAT plasminogen activator, tissue
POLL polymerase (DNA directed), lambda
PRDX1 peroxiredoxin 1
PTGIS prostaglandin I2 (prostacyclin) synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH parathyroid hormone
PTH1R parathyroid hormone 1 receptor
PTK2 protein tyrosine kinase 2
PTN pleiotrophin
PTX3 pentraxin 3, long
PXN paxillin
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
REST RE1-silencing transcription factor
RHOA ras homolog family member A
RNF213 ring finger protein 213
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RTN4 reticulon 4
RUNX2 runt-related transcription factor 2
S100A12 S100 calcium binding protein A12
SCN11A sodium channel, voltage gated, type XI alpha subunit
SDC4 syndecan 4
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SFTPB surfactant protein B
SGK1 serum/glucocorticoid regulated kinase 1
SIRT1 sirtuin 1
SMAD3 SMAD family member 3
SOCS1 suppressor of cytokine signaling 1
SOST sclerostin
SOX9 SRY (sex determining region Y)-box 9
SP7 Sp7 transcription factor
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPP1 secreted phosphoprotein 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSPN sarcospan
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STC1 stanniocalcin 1
SYT1 synaptotagmin I
TAC1 tachykinin, precursor 1
TCAP titin-cap
TGFB1 transforming growth factor, beta 1
TGFB3 transforming growth factor, beta 3
TGM2 transglutaminase 2
THBD thrombomodulin
THY1 Thy-1 cell surface antigen
TIAM1 T-cell lymphoma invasion and metastasis 1
TIMP2 TIMP metallopeptidase inhibitor 2
TLN1 talin 1
TNC tenascin C
TNF tumor necrosis factor
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNNI3 troponin I type 3 (cardiac)
TNNT2 troponin T type 2 (cardiac)
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TTN titin
UBC ubiquitin C
VASP vasodilator-stimulated phosphoprotein
VCL vinculin
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VIM vimentin
VKORC1 vitamin K epoxide reductase complex, subunit 1
WNT3A wingless-type MMTV integration site family, member 3A
WWTR1 WW domain containing transcription regulator 1
XYLT1 xylosyltransferase I
YAP1 Yes-associated protein 1
YY1AP1 YY1 associated protein 1
ZYX zyxin