meclocycline-3277 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

198 genes differentially expressed following the meclocycline-3277 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCK2 aarF domain containing kinase 2
AMPD3 adenosine monophosphate deaminase 3
APOM apolipoprotein M
ARRB2 arrestin, beta 2
ASPH aspartate beta-hydroxylase
ATAD3A ATPase family, AAA domain containing 3A
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
C10ORF12 chromosome 10 open reading frame 12
C11ORF63 chromosome 11 open reading frame 63
C20ORF27 chromosome 20 open reading frame 27
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CAMTA2 calmodulin binding transcription activator 2
CASP2 caspase 2, apoptosis-related cysteine peptidase
CD58 CD58 molecule
CDC14B cell division cycle 14B
CEP250 centrosomal protein 250kDa
CHST10 carbohydrate sulfotransferase 10
CLCN7 chloride channel, voltage-sensitive 7
CXCL12 chemokine (C-X-C motif) ligand 12
DBF4B DBF4 zinc finger B
DGCR8 DGCR8 microprocessor complex subunit
DMTN dematin actin binding protein
EGFL7 EGF-like-domain, multiple 7
EGR3 early growth response 3
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
FMOD fibromodulin
GJB3 gap junction protein, beta 3, 31kDa
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GOLGA2 golgin A2
GPR15 G protein-coupled receptor 15
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H1D histone cluster 1, H1d
ICOSLG inducible T-cell co-stimulator ligand
IFT54 intraflagellar transport 54
IGFBP5 insulin-like growth factor binding protein 5
IGHA1 immunoglobulin heavy constant alpha 1
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCNK12 potassium channel, two pore domain subfamily K, member 12
KRIT1 KRIT1, ankyrin repeat containing
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LMF2 lipase maturation factor 2
LMO4 LIM domain only 4
LTB4R leukotriene B4 receptor
LYZL6 lysozyme-like 6
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MALL mal, T-cell differentiation protein-like
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAU2 MAU2 sister chromatid cohesion factor
MET MET proto-oncogene, receptor tyrosine kinase
MFAP3 microfibrillar-associated protein 3
MMRN2 multimerin 2
MOCS1 molybdenum cofactor synthesis 1
MOCS3 molybdenum cofactor synthesis 3
MTA1 metastasis associated 1
MTM1 myotubularin 1
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYB v-myb avian myeloblastosis viral oncogene homolog
MYH14 myosin, heavy chain 14, non-muscle
MYOF myoferlin
NDRG2 NDRG family member 2
NRSN2 neurensin 2
NT5E 5'-nucleotidase, ecto (CD73)
NUMA1 nuclear mitotic apparatus protein 1
ORC5 origin recognition complex, subunit 5
PAIP2B poly(A) binding protein interacting protein 2B
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PEX1 peroxisomal biogenesis factor 1
PICK1 protein interacting with PRKCA 1
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLAGL1 pleiomorphic adenoma gene-like 1
PLK3 polo-like kinase 3
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POFUT1 protein O-fucosyltransferase 1
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
PROL1 proline rich, lacrimal 1
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PVR poliovirus receptor
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RYR1 ryanodine receptor 1 (skeletal)
SFXN1 sideroflexin 1
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SNCAIP synuclein, alpha interacting protein
SORBS3 sorbin and SH3 domain containing 3
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
STX1A syntaxin 1A (brain)
SYMPK symplekin
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TBCD tubulin folding cofactor D
TBX5 T-box 5
TMEM254 transmembrane protein 254
TRIM29 tripartite motif containing 29
TRIM38 tripartite motif containing 38
UBE3B ubiquitin protein ligase E3B
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF365 zinc finger protein 365
ZNF771 zinc finger protein 771

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APOLD1 apolipoprotein L domain containing 1
ARRB1 arrestin, beta 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BCL9 B-cell CLL/lymphoma 9
BCORL1 BCL6 corepressor-like 1
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BIK BCL2-interacting killer (apoptosis-inducing)
C11ORF30 chromosome 11 open reading frame 30
C14ORF93 chromosome 14 open reading frame 93
C9ORF9 chromosome 9 open reading frame 9
CCNO cyclin O
CIC capicua transcriptional repressor
CLCN6 chloride channel, voltage-sensitive 6
CNGB3 cyclic nucleotide gated channel beta 3
DUSP13 dual specificity phosphatase 13
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFHD2 EF-hand domain family, member D2
EFNA3 ephrin-A3
EMID1 EMI domain containing 1
EPN3 epsin 3
EXD3 exonuclease 3'-5' domain containing 3
F2R coagulation factor II (thrombin) receptor
FAAH fatty acid amide hydrolase
FAM131A family with sequence similarity 131, member A
FANCE Fanconi anemia, complementation group E
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FER fer (fps/fes related) tyrosine kinase
FILIP1L filamin A interacting protein 1-like
FOXN2 forkhead box N2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GPR27 G protein-coupled receptor 27
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HIST1H2BO histone cluster 1, H2bo
HIST1H4F histone cluster 1, H4f
HPS6 Hermansky-Pudlak syndrome 6
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
JMJD4 jumonji domain containing 4
KIAA0513 KIAA0513
KLK5 kallikrein-related peptidase 5
LOC257152 uncharacterized LOC257152
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRRC20 leucine rich repeat containing 20
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MANBA mannosidase, beta A, lysosomal
NPTX1 neuronal pentraxin I
ORAI3 ORAI calcium release-activated calcium modulator 3
PACS1 phosphofurin acidic cluster sorting protein 1
PCDHB13 protocadherin beta 13
PLEKHA6 pleckstrin homology domain containing, family A member 6
PP14571 uncharacterized LOC100130449
PRAF2 PRA1 domain family, member 2
PRAMEF11 PRAME family member 11
PRICKLE3 prickle homolog 3 (Drosophila)
PRR4 proline rich 4 (lacrimal)
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RNF31 ring finger protein 31
SCN1B sodium channel, voltage gated, type I beta subunit
SLC12A8 solute carrier family 12, member 8
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC38A10 solute carrier family 38, member 10
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SPRY2 sprouty homolog 2 (Drosophila)
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAG3 stromal antigen 3
STIM1 stromal interaction molecule 1
STRN striatin, calmodulin binding protein
TAOK1 TAO kinase 1
TBC1D17 TBC1 domain family, member 17
TCHH trichohyalin
TCTN1 tectonic family member 1
TEAD3 TEA domain family member 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM183A transmembrane protein 183A
TMEM209 transmembrane protein 209
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNS2 tensin 2
TPCN1 two pore segment channel 1
TRIM5 tripartite motif containing 5
TWF2 twinfilin actin binding protein 2
USP20 ubiquitin specific peptidase 20
USP27X ubiquitin specific peptidase 27, X-linked
VEGFC vascular endothelial growth factor C
VGF VGF nerve growth factor inducible
WFDC2 WAP four-disulfide core domain 2
XAB2 XPA binding protein 2
ZBTB44 zinc finger and BTB domain containing 44
ZMAT5 zinc finger, matrin-type 5
ZNF329 zinc finger protein 329
ZNF747 zinc finger protein 747