| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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193 genes differentially expressed following the meclocycline-6637 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) |
| ACHE | acetylcholinesterase (Yt blood group) |
| ACSM1 | acyl-CoA synthetase medium-chain family member 1 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| ADRBK2 | adrenergic, beta, receptor kinase 2 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| ATXN7L1 | ataxin 7-like 1 |
| BMP2 | bone morphogenetic protein 2 |
| BMP7 | bone morphogenetic protein 7 |
| BTG2 | BTG family, member 2 |
| C10ORF12 | chromosome 10 open reading frame 12 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C1QB | complement component 1, q subcomponent, B chain |
| C22ORF24 | chromosome 22 open reading frame 24 |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) |
| CD300A | CD300a molecule |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLDN10 | claudin 10 |
| DGKQ | diacylglycerol kinase, theta 110kDa |
| EMID1 | EMI domain containing 1 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FAM46C | family with sequence similarity 46, member C |
| FLT1 | fms-related tyrosine kinase 1 |
| FRZB | frizzled-related protein |
| GLRA3 | glycine receptor, alpha 3 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GPR135 | G protein-coupled receptor 135 |
| HBB | hemoglobin, beta |
| HOXC5 | homeobox C5 |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| IFI44 | interferon-induced protein 44 |
| IGHM | immunoglobulin heavy constant mu |
| IL11 | interleukin 11 |
| ING2 | inhibitor of growth family, member 2 |
| ING4 | inhibitor of growth family, member 4 |
| JAK3 | Janus kinase 3 |
| JUND | jun D proto-oncogene |
| KCNA3 | potassium channel, voltage gated shaker related subfamily A, member 3 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KDM4C | lysine (K)-specific demethylase 4C |
| KLHL25 | kelch-like family member 25 |
| KRT23 | keratin 23, type I |
| LAT2 | linker for activation of T cells family, member 2 |
| LIMD1 | LIM domains containing 1 |
| LMTK2 | lemur tyrosine kinase 2 |
| LOC157562 | uncharacterized LOC157562 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MCOLN3 | mucolipin 3 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MECOM | MDS1 and EVI1 complex locus |
| MVB12B | multivesicular body subunit 12B |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NF1 | neurofibromin 1 |
| NNMT | nicotinamide N-methyltransferase |
| NPAS1 | neuronal PAS domain protein 1 |
| NTNG1 | netrin G1 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PALM | paralemmin |
| PCDHGA3 | protocadherin gamma subfamily A, 3 |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| PODNL1 | podocan-like 1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PROL1 | proline rich, lacrimal 1 |
| PRY | PTPN13-like, Y-linked |
| PTGER1 | prostaglandin E receptor 1 (subtype EP1), 42kDa |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 |
| PTPN7 | protein tyrosine phosphatase, non-receptor type 7 |
| RARG | retinoic acid receptor, gamma |
| RASAL2 | RAS protein activator like 2 |
| RASSF4 | Ras association (RalGDS/AF-6) domain family member 4 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase |
| RUNX1 | runt-related transcription factor 1 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLC9A7 | solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STAB2 | stabilin 2 |
| STS | steroid sulfatase (microsomal), isozyme S |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TBRG4 | transforming growth factor beta regulator 4 |
| THOC5 | THO complex 5 |
| TLN2 | talin 2 |
| TMEM231 | transmembrane protein 231 |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TSC22D4 | TSC22 domain family, member 4 |
| USH1C | Usher syndrome 1C (autosomal recessive, severe) |
| WNK1 | WNK lysine deficient protein kinase 1 |
| ZNF24 | zinc finger protein 24 |
| ZNF79 | zinc finger protein 79 |
| ZSCAN32 | zinc finger and SCAN domain containing 32 |
| Symbol | Name |
|---|---|
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| ABHD8 | abhydrolase domain containing 8 |
| AFF4 | AF4/FMR2 family, member 4 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ANKRD36 | ankyrin repeat domain 36 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ATAD2B | ATPase family, AAA domain containing 2B |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CENPO | centromere protein O |
| CHML | choroideremia-like (Rab escort protein 2) |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CPA4 | carboxypeptidase A4 |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DDN | dendrin |
| DENND4A | DENN/MADD domain containing 4A |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| EXOC6B | exocyst complex component 6B |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| F7 | coagulation factor VII (serum prothrombin conversion accelerator) |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FBXO40 | F-box protein 40 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GJC1 | gap junction protein, gamma 1, 45kDa |
| GPR1 | G protein-coupled receptor 1 |
| HAMP | hepcidin antimicrobial peptide |
| HCRP1 | hepatocellular carcinoma-related HCRP1 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AK | histone cluster 1, H2ak |
| HPN | hepsin |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| IBA57 | IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IL15RA | interleukin 15 receptor, alpha |
| IPO8 | importin 8 |
| KATNBL1 | katanin p80 subunit B-like 1 |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| KRT20 | keratin 20, type I |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LMNB1 | lamin B1 |
| LMO7 | LIM domain 7 |
| LOC100287590 | uncharacterized LOC100287590 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LTC4S | leukotriene C4 synthase |
| MMP10 | matrix metallopeptidase 10 |
| MMP9 | matrix metallopeptidase 9 |
| MTSS1L | metastasis suppressor 1-like |
| MUC3A | mucin 3A, cell surface associated |
| MYLIP | myosin regulatory light chain interacting protein |
| MYOZ3 | myozenin 3 |
| NEUROD4 | neuronal differentiation 4 |
| NKX3-2 | NK3 homeobox 2 |
| NOL12 | nucleolar protein 12 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 |
| QSER1 | glutamine and serine rich 1 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SIX3 | SIX homeobox 3 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SYCP2 | synaptonemal complex protein 2 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TESK1 | testis-specific kinase 1 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| TUBA3C | tubulin, alpha 3c |
| TUBB2B | tubulin, beta 2B class IIb |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VNN1 | vanin 1 |
| WDR18 | WD repeat domain 18 |
| WDR62 | WD repeat domain 62 |
| WFDC2 | WAP four-disulfide core domain 2 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF253 | zinc finger protein 253 |
| ZNF358 | zinc finger protein 358 |
| ZNF770 | zinc finger protein 770 |
| ZXDB | zinc finger, X-linked, duplicated B |