meclofenamic acid-1445 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the meclofenamic acid-1445 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ACOT11 acyl-CoA thioesterase 11
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AKAP7 A kinase (PRKA) anchor protein 7
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7
BAHCC1 BAH domain and coiled-coil containing 1
BCL3 B-cell CLL/lymphoma 3
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C2ORF27A chromosome 2 open reading frame 27A
C6 complement component 6
CA12 carbonic anhydrase XII
CA7 carbonic anhydrase VII
CCDC177 coiled-coil domain containing 177
CCDC64 coiled-coil domain containing 64
CD40 CD40 molecule, TNF receptor superfamily member 5
CLDN7 claudin 7
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa
CUL4B cullin 4B
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DEPTOR DEP domain containing MTOR-interacting protein
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DIO2 deiodinase, iodothyronine, type II
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DTNA dystrobrevin, alpha
EDA ectodysplasin A
EFR3B EFR3 homolog B (S. cerevisiae)
EIF4E2 eukaryotic translation initiation factor 4E family member 2
EPOR erythropoietin receptor
FAM3A family with sequence similarity 3, member A
FAM76A family with sequence similarity 76, member A
FLOT2 flotillin 2
GINS3 GINS complex subunit 3 (Psf3 homolog)
GK glycerol kinase
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GOSR2 golgi SNAP receptor complex member 2
GRK5 G protein-coupled receptor kinase 5
HFE hemochromatosis
HLA-DOA major histocompatibility complex, class II, DO alpha
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
IPO8 importin 8
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KCTD20 potassium channel tetramerization domain containing 20
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
LDOC1 leucine zipper, down-regulated in cancer 1
LEFTY2 left-right determination factor 2
LOC390998 ribosomal protein L10 pseudogene
MARK4 MAP/microtubule affinity-regulating kinase 4
MED18 mediator complex subunit 18
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NMD3 NMD3 ribosome export adaptor
NR2F2 nuclear receptor subfamily 2, group F, member 2
ONECUT2 one cut homeobox 2
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PCGF2 polycomb group ring finger 2
PCSK7 proprotein convertase subtilisin/kexin type 7
PEX1 peroxisomal biogenesis factor 1
PKNOX2 PBX/knotted 1 homeobox 2
PLCD1 phospholipase C, delta 1
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRPH2 peripherin 2 (retinal degeneration, slow)
PRY PTPN13-like, Y-linked
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RAMP3 receptor (G protein-coupled) activity modifying protein 3
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RRP1B ribosomal RNA processing 1B
RSPH6A radial spoke head 6 homolog A (Chlamydomonas)
SEC23A Sec23 homolog A (S. cerevisiae)
SH2D1A SH2 domain containing 1A
SKAP1 src kinase associated phosphoprotein 1
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SNAP23 synaptosomal-associated protein, 23kDa
STAC SH3 and cysteine rich domain
SUGP1 SURP and G patch domain containing 1
SYP synaptophysin
SYT13 synaptotagmin XIII
TET3 tet methylcytosine dioxygenase 3
TGFB3 transforming growth factor, beta 3
TM7SF2 transmembrane 7 superfamily member 2
TMEM156 transmembrane protein 156
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TOX4 TOX high mobility group box family member 4
TUBA4B tubulin, alpha 4b
UPK1B uroplakin 1B
URI1 URI1, prefoldin-like chaperone
VARS valyl-tRNA synthetase
VCX2 variable charge, X-linked 2
VGF VGF nerve growth factor inducible
YIPF1 Yip1 domain family, member 1
ZBTB7A zinc finger and BTB domain containing 7A
ZC3H12A zinc finger CCCH-type containing 12A
ZNF248 zinc finger protein 248

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ANPEP alanyl (membrane) aminopeptidase
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARHGAP4 Rho GTPase activating protein 4
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BATF3 basic leucine zipper transcription factor, ATF-like 3
BCKDK branched chain ketoacid dehydrogenase kinase
BCL7C B-cell CLL/lymphoma 7C
C12ORF29 chromosome 12 open reading frame 29
C2CD3 C2 calcium-dependent domain containing 3
CAPN15 calpain 15
CCNT1 cyclin T1
CDC42SE1 CDC42 small effector 1
CDCA3 cell division cycle associated 3
CDKN2AIP CDKN2A interacting protein
CEP72 centrosomal protein 72kDa
CEP85 centrosomal protein 85kDa
CISH cytokine inducible SH2-containing protein
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CUEDC2 CUE domain containing 2
CYTH2 cytohesin 2
DDB2 damage-specific DNA binding protein 2, 48kDa
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32
DPYD dihydropyrimidine dehydrogenase
DUSP22 dual specificity phosphatase 22
FAM114A2 family with sequence similarity 114, member A2
FAM53B family with sequence similarity 53, member B
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCHO1 FCH domain only 1
GATAD2A GATA zinc finger domain containing 2A
GBAP1 glucosidase, beta, acid pseudogene 1
GCLM glutamate-cysteine ligase, modifier subunit
GMEB1 glucocorticoid modulatory element binding protein 1
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HELLS helicase, lymphoid-specific
HIRA histone cell cycle regulator
HK1 hexokinase 1
IFITM3 interferon induced transmembrane protein 3
IFNA17 interferon, alpha 17
IL2RG interleukin 2 receptor, gamma
ISCU iron-sulfur cluster assembly enzyme
KLF13 Kruppel-like factor 13
LMO2 LIM domain only 2 (rhombotin-like 1)
LONRF3 LON peptidase N-terminal domain and ring finger 3
LRP10 low density lipoprotein receptor-related protein 10
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGT1 magnesium transporter 1
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MCM9 minichromosome maintenance complex component 9
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MT1HL1 metallothionein 1H-like 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MXRA8 matrix-remodelling associated 8
MYL12B myosin, light chain 12B, regulatory
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NMB neuromedin B
NR1H2 nuclear receptor subfamily 1, group H, member 2
OXR1 oxidation resistance 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PAK1IP1 PAK1 interacting protein 1
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
PIGP phosphatidylinositol glycan anchor biosynthesis, class P
PLAG1 pleiomorphic adenoma gene 1
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PRKX protein kinase, X-linked
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RABGGTA Rab geranylgeranyltransferase, alpha subunit
REPIN1 replication initiator 1
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RWDD3 RWD domain containing 3
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERTAD3 SERTA domain containing 3
SETD1B SET domain containing 1B
SIPA1 signal-induced proliferation-associated 1
SKI SKI proto-oncogene
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SNAP29 synaptosomal-associated protein, 29kDa
SPC25 SPC25, NDC80 kinetochore complex component
ST7 suppression of tumorigenicity 7
TAOK1 TAO kinase 1
TERT telomerase reverse transcriptase
THOP1 thimet oligopeptidase 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TPRA1 transmembrane protein, adipocyte asscociated 1
TRAPPC12 trafficking protein particle complex 12
TRHDE thyrotropin-releasing hormone degrading enzyme
TST thiosulfate sulfurtransferase (rhodanese)
TTC23 tetratricopeptide repeat domain 23
TUBA3C tubulin, alpha 3c
WBP2 WW domain binding protein 2
YIPF5 Yip1 domain family, member 5
ZNF273 zinc finger protein 273