meclofenamic acid-2291 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the meclofenamic acid-2291 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
ANG angiogenin, ribonuclease, RNase A family, 5
ANKRD7 ankyrin repeat domain 7
ASPN asporin
ATG10 autophagy related 10
ATP10B ATPase, class V, type 10B
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CA5B carbonic anhydrase VB, mitochondrial
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCL27 chemokine (C-C motif) ligand 27
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CERS4 ceramide synthase 4
CLEC2B C-type lectin domain family 2, member B
COL13A1 collagen, type XIII, alpha 1
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CRMP1 collapsin response mediator protein 1
CRYGD crystallin, gamma D
CTIF CBP80/20-dependent translation initiation factor
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DMPK dystrophia myotonica-protein kinase
DTX2 deltex 2, E3 ubiquitin ligase
EFCAB11 EF-hand calcium binding domain 11
EMID1 EMI domain containing 1
ETV7 ets variant 7
FBXO21 F-box protein 21
FGD1 FYVE, RhoGEF and PH domain containing 1
FRMD1 FERM domain containing 1
FXYD5 FXYD domain containing ion transport regulator 5
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GPATCH4 G patch domain containing 4
GSK3A glycogen synthase kinase 3 alpha
H2AFX H2A histone family, member X
HIF3A hypoxia inducible factor 3, alpha subunit
HOXB2 homeobox B2
IBSP integrin-binding sialoprotein
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3
KAT6A K(lysine) acetyltransferase 6A
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LPAR3 lysophosphatidic acid receptor 3
LRRC1 leucine rich repeat containing 1
MAB21L1 mab-21-like 1 (C. elegans)
MAP2K7 mitogen-activated protein kinase kinase 7
MARK4 MAP/microtubule affinity-regulating kinase 4
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MX2 MX dynamin-like GTPase 2
MYBPC3 myosin binding protein C, cardiac
NOTCH4 notch 4
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OPRM1 opioid receptor, mu 1
OR2B6 olfactory receptor, family 2, subfamily B, member 6
OSBP2 oxysterol binding protein 2
PCDHA9 protocadherin alpha 9
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
POU2F2 POU class 2 homeobox 2
PRB1 proline-rich protein BstNI subfamily 1
PROM1 prominin 1
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
REC8 REC8 meiotic recombination protein
RGS14 regulator of G-protein signaling 14
RIF1 replication timing regulatory factor 1
RIN3 Ras and Rab interactor 3
RORC RAR-related orphan receptor C
SCD5 stearoyl-CoA desaturase 5
SCN11A sodium channel, voltage gated, type XI alpha subunit
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SH3D21 SH3 domain containing 21
SLC39A9 solute carrier family 39, member 9
SOGA1 suppressor of glucose, autophagy associated 1
SPTBN1 spectrin, beta, non-erythrocytic 1
STAT2 signal transducer and activator of transcription 2, 113kDa
SWAP70 SWAP switching B-cell complex 70kDa subunit
SYT5 synaptotagmin V
TBX5 T-box 5
TCEAL2 transcription elongation factor A (SII)-like 2
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TJAP1 tight junction associated protein 1 (peripheral)
TLR2 toll-like receptor 2
TMEM246 transmembrane protein 246
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRBC1 T cell receptor beta constant 1
TRIL TLR4 interactor with leucine-rich repeats
TSC2 tuberous sclerosis 2
WNT10B wingless-type MMTV integration site family, member 10B
ZFPL1 zinc finger protein-like 1
ZNF205 zinc finger protein 205
ZNF235 zinc finger protein 235
ZNF528 zinc finger protein 528
ZNF589 zinc finger protein 589
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
AHSP alpha hemoglobin stabilizing protein
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BEGAIN brain-enriched guanylate kinase-associated
BFSP1 beaded filament structural protein 1, filensin
C3 complement component 3
C9ORF9 chromosome 9 open reading frame 9
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAMK4 calcium/calmodulin-dependent protein kinase IV
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CHKB choline kinase beta
CLGN calmegin
CORO7 coronin 7
CRLF1 cytokine receptor-like factor 1
DCAF4 DDB1 and CUL4 associated factor 4
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DGKE diacylglycerol kinase, epsilon 64kDa
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNALI1 dynein, axonemal, light intermediate chain 1
ELOVL4 ELOVL fatty acid elongase 4
ERCC4 excision repair cross-complementation group 4
ETNK2 ethanolamine kinase 2
FAM120C family with sequence similarity 120C
FAM131A family with sequence similarity 131, member A
FAM212B family with sequence similarity 212, member B
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GPR143 G protein-coupled receptor 143
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H2AI histone cluster 1, H2ai
HP1BP3 heterochromatin protein 1, binding protein 3
HYI hydroxypyruvate isomerase (putative)
IFT81 intraflagellar transport 81
IL12RB1 interleukin 12 receptor, beta 1
IL17RA interleukin 17 receptor A
IPO8 importin 8
IQCG IQ motif containing G
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KIAA0319L KIAA0319-like
KIAA1107 KIAA1107
KREMEN2 kringle containing transmembrane protein 2
LAS1L LAS1-like (S. cerevisiae)
LOXL3 lysyl oxidase-like 3
MAGEB2 melanoma antigen family B2
MAL mal, T-cell differentiation protein
MBTD1 mbt domain containing 1
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MTCP1 mature T-cell proliferation 1
MTHFSD methenyltetrahydrofolate synthetase domain containing
MXD3 MAX dimerization protein 3
MYF5 myogenic factor 5
MYO1E myosin IE
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NME5 NME/NM23 family member 5
NYNRIN NYN domain and retroviral integrase containing
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLEKHS1 pleckstrin homology domain containing, family S member 1
PYHIN1 pyrin and HIN domain family, member 1
QTRT1 queuine tRNA-ribosyltransferase 1
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RFXAP regulatory factor X-associated protein
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
S100A2 S100 calcium binding protein A2
S100A9 S100 calcium binding protein A9
SENP7 SUMO1/sentrin specific peptidase 7
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLIT2 slit homolog 2 (Drosophila)
TBC1D2 TBC1 domain family, member 2
TET3 tet methylcytosine dioxygenase 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM209 transmembrane protein 209
TMOD1 tropomodulin 1
TRDMT1 tRNA aspartic acid methyltransferase 1
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UPK3B uroplakin 3B
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
WDR62 WD repeat domain 62
ZBTB22 zinc finger and BTB domain containing 22
ZFP37 ZFP37 zinc finger protein
ZNF10 zinc finger protein 10
ZNF136 zinc finger protein 136
ZNF280D zinc finger protein 280D
ZNF37BP zinc finger protein 37B, pseudogene
ZNF652 zinc finger protein 652