meclofenamic acid-7038 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the meclofenamic acid-7038 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM17 ADAM metallopeptidase domain 17
ALCAM activated leukocyte cell adhesion molecule
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARTN artemin
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
B9D1 B9 protein domain 1
C6ORF10 chromosome 6 open reading frame 10
C7ORF43 chromosome 7 open reading frame 43
CAMTA1 calmodulin binding transcription activator 1
CAPN9 calpain 9
CASP3 caspase 3, apoptosis-related cysteine peptidase
CDK3 cyclin-dependent kinase 3
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CLIP1 CAP-GLY domain containing linker protein 1
CNGB3 cyclic nucleotide gated channel beta 3
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CSF1R colony stimulating factor 1 receptor
DGAT1 diacylglycerol O-acyltransferase 1
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
EFHD1 EF-hand domain family, member D1
ELOVL5 ELOVL fatty acid elongase 5
FAM49B family with sequence similarity 49, member B
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
GADD45G growth arrest and DNA-damage-inducible, gamma
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GID4 GID complex subunit 4
GOSR1 golgi SNAP receptor complex member 1
GSK3A glycogen synthase kinase 3 alpha
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IQCC IQ motif containing C
IQCK IQ motif containing K
LAMP3 lysosomal-associated membrane protein 3
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LIN7A lin-7 homolog A (C. elegans)
LINC00115 long intergenic non-protein coding RNA 115
LRP6 low density lipoprotein receptor-related protein 6
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MCM3AP minichromosome maintenance complex component 3 associated protein
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEG3 maternally expressed 3 (non-protein coding)
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MIIP migration and invasion inhibitory protein
N4BP2L2 NEDD4 binding protein 2-like 2
NCOA2 nuclear receptor coactivator 2
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NF1 neurofibromin 1
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NLRX1 NLR family member X1
NPHP4 nephronophthisis 4
NPPA natriuretic peptide A
NRN1 neuritin 1
NRSN2 neurensin 2
OASL 2'-5'-oligoadenylate synthetase-like
PAPOLG poly(A) polymerase gamma
PDGFA platelet-derived growth factor alpha polypeptide
PHF2 PHD finger protein 2
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PKNOX1 PBX/knotted 1 homeobox 1
PLAGL1 pleiomorphic adenoma gene-like 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PLK3 polo-like kinase 3
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PPAP2B phosphatidic acid phosphatase type 2B
PRKD3 protein kinase D3
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PTPRA protein tyrosine phosphatase, receptor type, A
PTRF polymerase I and transcript release factor
RABGAP1 RAB GTPase activating protein 1
RANBP1 RAN binding protein 1
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RGS12 regulator of G-protein signaling 12
SARS2 seryl-tRNA synthetase 2, mitochondrial
SIK3 SIK family kinase 3
SIM2 single-minded family bHLH transcription factor 2
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SMG5 SMG5 nonsense mediated mRNA decay factor
SOX9 SRY (sex determining region Y)-box 9
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SPAST spastin
ST20 suppressor of tumorigenicity 20
ST7 suppression of tumorigenicity 7
TCHH trichohyalin
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TJAP1 tight junction associated protein 1 (peripheral)
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TUBA3C tubulin, alpha 3c
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
WNT10B wingless-type MMTV integration site family, member 10B
YPEL1 yippee-like 1 (Drosophila)
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF197 zinc finger protein 197

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ADGRE5 adhesion G protein-coupled receptor E5
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ANXA2P3 annexin A2 pseudogene 3
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
BAK1 BCL2-antagonist/killer 1
BCOR BCL6 corepressor
BRAF B-Raf proto-oncogene, serine/threonine kinase
C14ORF132 chromosome 14 open reading frame 132
C16ORF45 chromosome 16 open reading frame 45
C16ORF59 chromosome 16 open reading frame 59
CDH10 cadherin 10, type 2 (T2-cadherin)
CDK20 cyclin-dependent kinase 20
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEP131 centrosomal protein 131kDa
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
DCAF13 DDB1 and CUL4 associated factor 13
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DMTN dematin actin binding protein
ECHDC2 enoyl CoA hydratase domain containing 2
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
ELP3 elongator acetyltransferase complex subunit 3
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ETAA1 Ewing tumor-associated antigen 1
FBXO46 F-box protein 46
FMO4 flavin containing monooxygenase 4
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GIF gastric intrinsic factor (vitamin B synthesis)
GPATCH3 G patch domain containing 3
GPR68 G protein-coupled receptor 68
GRTP1 growth hormone regulated TBC protein 1
HIST1H2AL histone cluster 1, H2al
HPS6 Hermansky-Pudlak syndrome 6
HPSE heparanase
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IFT140 intraflagellar transport 140
IRF1 interferon regulatory factor 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
KLHL25 kelch-like family member 25
KRT13 keratin 13, type I
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LOC390998 ribosomal protein L10 pseudogene
LY6D lymphocyte antigen 6 complex, locus D
MFAP2 microfibrillar-associated protein 2
MMP9 matrix metallopeptidase 9
MYO1E myosin IE
NCAM2 neural cell adhesion molecule 2
NEK3 NIMA-related kinase 3
NR1H3 nuclear receptor subfamily 1, group H, member 3
P3H1 prolyl 3-hydroxylase 1
PARD6A par-6 family cell polarity regulator alpha
PARP12 poly (ADP-ribose) polymerase family, member 12
PDE12 phosphodiesterase 12
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PRPH peripherin
PXDC1 PX domain containing 1
PYCRL pyrroline-5-carboxylate reductase-like
RAB3A RAB3A, member RAS oncogene family
RASAL1 RAS protein activator like 1 (GAP1 like)
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
REEP4 receptor accessory protein 4
RIN1 Ras and Rab interactor 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPL13P5 ribosomal protein L13 pseudogene 5
SIK1 salt-inducible kinase 1
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLMO1 slowmo homolog 1 (Drosophila)
SNAI2 snail family zinc finger 2
SOX12 SRY (sex determining region Y)-box 12
STX1A syntaxin 1A (brain)
TBC1D12 TBC1 domain family, member 12
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TCTN1 tectonic family member 1
TCTN2 tectonic family member 2
THBS3 thrombospondin 3
THRAP3 thyroid hormone receptor associated protein 3
TIGD6 tigger transposable element derived 6
TRAIP TRAF interacting protein
TUBG2 tubulin, gamma 2
USP6NL USP6 N-terminal like
VEGFC vascular endothelial growth factor C
WDR4 WD repeat domain 4
WDR46 WD repeat domain 46
XYLT2 xylosyltransferase II
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZDHHC18 zinc finger, DHHC-type containing 18
ZFP69B ZFP69 zinc finger protein B
ZMAT5 zinc finger, matrin-type 5
ZNF34 zinc finger protein 34
ZNF350 zinc finger protein 350
ZNF747 zinc finger protein 747
ZNF816 zinc finger protein 816
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