meclofenoxate-3605 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the meclofenoxate-3605 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMDEC1 ADAM-like, decysin 1
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
AGXT alanine-glyoxylate aminotransferase
ANGPTL2 angiopoietin-like 2
APAF1 apoptotic peptidase activating factor 1
ARC activity-regulated cytoskeleton-associated protein
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CCDC64 coiled-coil domain containing 64
CCL19 chemokine (C-C motif) ligand 19
CCR8 chemokine (C-C motif) receptor 8
CFAP74 cilia and flagella associated protein 74
CLDN17 claudin 17
CMKLR1 chemerin chemokine-like receptor 1
CNTD2 cyclin N-terminal domain containing 2
CSF1 colony stimulating factor 1 (macrophage)
CTIF CBP80/20-dependent translation initiation factor
CXCL8 chemokine (C-X-C motif) ligand 8
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DBT dihydrolipoamide branched chain transacylase E2
DCN decorin
DESI2 desumoylating isopeptidase 2
DFNB31 deafness, autosomal recessive 31
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
ELAVL2 ELAV like neuron-specific RNA binding protein 2
ELMO1 engulfment and cell motility 1
FAM13A family with sequence similarity 13, member A
GFER growth factor, augmenter of liver regeneration
GGT1 gamma-glutamyltransferase 1
GJD2 gap junction protein, delta 2, 36kDa
GPR161 G protein-coupled receptor 161
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HIF3A hypoxia inducible factor 3, alpha subunit
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFNA14 interferon, alpha 14
IQCC IQ motif containing C
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
IZUMO4 IZUMO family member 4
KLHL29 kelch-like family member 29
KRT83 keratin 83, type II
LAMA4 laminin, alpha 4
LAT2 linker for activation of T cells family, member 2
LOC440895 two pore channel 3 pseudogene
LPAR1 lysophosphatidic acid receptor 1
LRRTM2 leucine rich repeat transmembrane neuronal 2
LTBP4 latent transforming growth factor beta binding protein 4
LTC4S leukotriene C4 synthase
LUZP4 leucine zipper protein 4
MARK4 MAP/microtubule affinity-regulating kinase 4
MSI1 musashi RNA-binding protein 1
MYT1 myelin transcription factor 1
NOTCH4 notch 4
OGFR opioid growth factor receptor
OR2F2 olfactory receptor, family 2, subfamily F, member 2
OSBPL3 oxysterol binding protein-like 3
PARVB parvin, beta
PIPOX pipecolic acid oxidase
PKNOX2 PBX/knotted 1 homeobox 2
PLAC4 placenta-specific 4
PLAT plasminogen activator, tissue
PLEK pleckstrin
PRF1 perforin 1 (pore forming protein)
PRKG2 protein kinase, cGMP-dependent, type II
PRPH2 peripherin 2 (retinal degeneration, slow)
RAD52 RAD52 homolog (S. cerevisiae)
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
S100A8 S100 calcium binding protein A8
SAFB scaffold attachment factor B
SAG S-antigen; retina and pineal gland (arrestin)
SCLY selenocysteine lyase
SH3BP2 SH3-domain binding protein 2
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SPN sialophorin
SPRR3 small proline-rich protein 3
SQSTM1 sequestosome 1
SV2C synaptic vesicle glycoprotein 2C
SYN3 synapsin III
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TBC1D2 TBC1 domain family, member 2
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
THRB thyroid hormone receptor, beta
THSD4 thrombospondin, type I, domain containing 4
TIMP3 TIMP metallopeptidase inhibitor 3
TNNI3 troponin I type 3 (cardiac)
TRIL TLR4 interactor with leucine-rich repeats
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae)
TTC28 tetratricopeptide repeat domain 28
ZMAT4 zinc finger, matrin-type 4
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
ACOT8 acyl-CoA thioesterase 8
APLP1 amyloid beta (A4) precursor-like protein 1
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
BBC3 BCL2 binding component 3
C11ORF80 chromosome 11 open reading frame 80
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAMK4 calcium/calmodulin-dependent protein kinase IV
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCDC9 coiled-coil domain containing 9
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CLSTN2 calsyntenin 2
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRYBB2P1 crystallin, beta B2 pseudogene 1
CTAGE9 CTAGE family, member 9
CUL9 cullin 9
CXADR coxsackie virus and adenovirus receptor
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DIO1 deiodinase, iodothyronine, type I
DNM3 dynamin 3
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ENO2 enolase 2 (gamma, neuronal)
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPN1 epsin 1
ERCC4 excision repair cross-complementation group 4
ERCC6 excision repair cross-complementation group 6
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM204A family with sequence similarity 204, member A
FGD1 FYVE, RhoGEF and PH domain containing 1
FGF23 fibroblast growth factor 23
GINS4 GINS complex subunit 4 (Sld5 homolog)
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H1D histone cluster 1, H1d
HOXC5 homeobox C5
HOXC8 homeobox C8
HP1BP3 heterochromatin protein 1, binding protein 3
IFNA17 interferon, alpha 17
IL12RB1 interleukin 12 receptor, beta 1
ITPKB inositol-trisphosphate 3-kinase B
JMJD4 jumonji domain containing 4
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
LARP6 La ribonucleoprotein domain family, member 6
LINC00115 long intergenic non-protein coding RNA 115
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAST3 microtubule associated serine/threonine kinase 3
MBTD1 mbt domain containing 1
MFSD11 major facilitator superfamily domain containing 11
MOB3B MOB kinase activator 3B
MTCP1 mature T-cell proliferation 1
NDE1 nudE neurodevelopment protein 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NIPAL2 NIPA-like domain containing 2
NME5 NME/NM23 family member 5
NPFFR1 neuropeptide FF receptor 1
NPIPB15 nuclear pore complex interacting protein family, member B15
NUPR1 nuclear protein, transcriptional regulator, 1
ONECUT2 one cut homeobox 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLSCR4 phospholipid scramblase 4
PMCH pro-melanin-concentrating hormone
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RBM41 RNA binding motif protein 41
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RNF122 ring finger protein 122
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPL13P5 ribosomal protein L13 pseudogene 5
SCGB2A2 secretoglobin, family 2A, member 2
SCN1B sodium channel, voltage gated, type I beta subunit
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SGCE sarcoglycan, epsilon
SHPK sedoheptulokinase
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SP1 Sp1 transcription factor
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TEP1 telomerase-associated protein 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TRIM16 tripartite motif containing 16
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TUBA3C tubulin, alpha 3c
VASH2 vasohibin 2
WDR76 WD repeat domain 76
WLS wntless Wnt ligand secretion mediator
ZFP37 ZFP37 zinc finger protein
ZNF480 zinc finger protein 480
ZNF652 zinc finger protein 652
ZNF721 zinc finger protein 721
ZNF767P zinc finger family member 767, pseudogene