meclofenoxate-3707 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the meclofenoxate-3707 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKAP8L A kinase (PRKA) anchor protein 8-like
ARTN artemin
BAAT bile acid CoA:amino acid N-acyltransferase
BBC3 BCL2 binding component 3
BCL6 B-cell CLL/lymphoma 6
BST1 bone marrow stromal cell antigen 1
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CALCR calcitonin receptor
CBLC Cbl proto-oncogene C, E3 ubiquitin protein ligase
CCDC121 coiled-coil domain containing 121
CCR9 chemokine (C-C motif) receptor 9
CD248 CD248 molecule, endosialin
CD86 CD86 molecule
CDHR2 cadherin-related family member 2
CGA glycoprotein hormones, alpha polypeptide
CIC capicua transcriptional repressor
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL14A1 collagen, type XIV, alpha 1
COMT catechol-O-methyltransferase
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DCN decorin
DKK3 dickkopf WNT signaling pathway inhibitor 3
DPY19L1P1 DPY19L1 pseudogene 1
DTNA dystrobrevin, alpha
EFCAB11 EF-hand calcium binding domain 11
EFCAB6 EF-hand calcium binding domain 6
EPB41L1 erythrocyte membrane protein band 4.1-like 1
EPHB1 EPH receptor B1
ERAP1 endoplasmic reticulum aminopeptidase 1
EYA1 EYA transcriptional coactivator and phosphatase 1
F2RL3 coagulation factor II (thrombin) receptor-like 3
FABP7 fatty acid binding protein 7, brain
FASLG Fas ligand (TNF superfamily, member 6)
FBXO40 F-box protein 40
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FGF22 fibroblast growth factor 22
FRMD4A FERM domain containing 4A
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GPR182 G protein-coupled receptor 182
GPR19 G protein-coupled receptor 19
HAL histidine ammonia-lyase
IGLJ3 immunoglobulin lambda joining 3
KANK1 KN motif and ankyrin repeat domains 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIAA0319L KIAA0319-like
KIF1A kinesin family member 1A
KLK10 kallikrein-related peptidase 10
KRT17 keratin 17, type I
LAMB4 laminin, beta 4
LRRC17 leucine rich repeat containing 17
LRRC75B leucine rich repeat containing 75B
LTBP4 latent transforming growth factor beta binding protein 4
MAP7D3 MAP7 domain containing 3
MATN1 matrilin 1, cartilage matrix protein
MC5R melanocortin 5 receptor
MEF2D myocyte enhancer factor 2D
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MUC5B mucin 5B, oligomeric mucus/gel-forming
NF1 neurofibromin 1
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
ONECUT2 one cut homeobox 2
OR2H2 olfactory receptor, family 2, subfamily H, member 2
PADI2 peptidyl arginine deiminase, type II
PDE10A phosphodiesterase 10A
PEX16 peroxisomal biogenesis factor 16
PLCB2 phospholipase C, beta 2
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRMT8 protein arginine methyltransferase 8
PROX1 prospero homeobox 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTN pleiotrophin
PTPRJ protein tyrosine phosphatase, receptor type, J
RAB6A RAB6A, member RAS oncogene family
RAB6B RAB6B, member RAS oncogene family
RASL11B RAS-like, family 11, member B
RGS12 regulator of G-protein signaling 12
RGS5 regulator of G-protein signaling 5
RIMS2 regulating synaptic membrane exocytosis 2
RPH3A rabphilin 3A
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SSX1 synovial sarcoma, X breakpoint 1
STAB2 stabilin 2
TIAM1 T-cell lymphoma invasion and metastasis 1
TLK1 tousled-like kinase 1
TLR1 toll-like receptor 1
TRIM29 tripartite motif containing 29
WDR59 WD repeat domain 59
WNT3 wingless-type MMTV integration site family, member 3
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YES1 YES proto-oncogene 1, Src family tyrosine kinase
ZIC4 Zic family member 4

decreased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
ANOS1 anosmin 1
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
APOLD1 apolipoprotein L domain containing 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
AXIN1 axin 1
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C5 complement component 5
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC94 coiled-coil domain containing 94
CCS copper chaperone for superoxide dismutase
CDH19 cadherin 19, type 2
CENPO centromere protein O
CES3 carboxylesterase 3
CFAP69 cilia and flagella associated protein 69
CLCA1 chloride channel accessory 1
CLCN6 chloride channel, voltage-sensitive 6
CLSTN3 calsyntenin 3
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CYBRD1 cytochrome b reductase 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DBR1 debranching RNA lariats 1
DENND2D DENN/MADD domain containing 2D
DIO3 deiodinase, iodothyronine, type III
EFNB1 ephrin-B1
EML4 echinoderm microtubule associated protein like 4
ERN2 endoplasmic reticulum to nucleus signaling 2
FGL1 fibrinogen-like 1
FKRP fukutin related protein
FOXD1 forkhead box D1
GRB7 growth factor receptor-bound protein 7
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
GTF2I general transcription factor IIi
HIST1H2AM histone cluster 1, H2am
HIST1H4C histone cluster 1, H4c
HLA-DMA major histocompatibility complex, class II, DM alpha
HOXA4 homeobox A4
HOXB9 homeobox B9
HSPA1L heat shock 70kDa protein 1-like
IGFLR1 IGF-like family receptor 1
INF2 inverted formin, FH2 and WH2 domain containing
ISYNA1 inositol-3-phosphate synthase 1
KIAA0754 KIAA0754
LIN7B lin-7 homolog B (C. elegans)
MCOLN1 mucolipin 1
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MRPL44 mitochondrial ribosomal protein L44
MYOZ3 myozenin 3
NECAP2 NECAP endocytosis associated 2
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NRTN neurturin
NT5M 5',3'-nucleotidase, mitochondrial
NXPE3 neurexophilin and PC-esterase domain family, member 3
OSMR oncostatin M receptor
OSR2 odd-skipped related transciption factor 2
PAIP2B poly(A) binding protein interacting protein 2B
PARP3 poly (ADP-ribose) polymerase family, member 3
PEX26 peroxisomal biogenesis factor 26
PLA2G15 phospholipase A2, group XV
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PODXL2 podocalyxin-like 2
PRR15L proline rich 15-like
PXMP4 peroxisomal membrane protein 4, 24kDa
RIN1 Ras and Rab interactor 1
RPA4 replication protein A4, 30kDa
RPL10L ribosomal protein L10-like
S100A3 S100 calcium binding protein A3
SAYSD1 SAYSVFN motif domain containing 1
SDC3 syndecan 3
SFMBT1 Scm-like with four mbt domains 1
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLITRK5 SLIT and NTRK-like family, member 5
SLN sarcolipin
STRN striatin, calmodulin binding protein
TBC1D2 TBC1 domain family, member 2
TGFB3 transforming growth factor, beta 3
TM7SF2 transmembrane 7 superfamily member 2
TMEM53 transmembrane protein 53
TMEM74B transmembrane protein 74B
TMEM8B transmembrane protein 8B
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TOR4A torsin family 4, member A
TPRA1 transmembrane protein, adipocyte asscociated 1
TRABD TraB domain containing
TRAC T cell receptor alpha constant
TSKU tsukushi, small leucine rich proteoglycan
TUBA3C tubulin, alpha 3c
TUBB2B tubulin, beta 2B class IIb
WDR18 WD repeat domain 18
ZBTB22 zinc finger and BTB domain containing 22
ZNF442 zinc finger protein 442
ZNF480 zinc finger protein 480
ZNF639 zinc finger protein 639
ZNF702P zinc finger protein 702, pseudogene
ZNF768 zinc finger protein 768