meclofenoxate-4729 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

197 genes differentially expressed following the meclofenoxate-4729 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCK4 aarF domain containing kinase 4
AHNAK AHNAK nucleoprotein
AMPD3 adenosine monophosphate deaminase 3
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
APC adenomatous polyposis coli
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGAP26 Rho GTPase activating protein 26
ATXN8OS ATXN8 opposite strand (non-protein coding)
BMP10 bone morphogenetic protein 10
BTF3P11 basic transcription factor 3 pseudogene 11
C1QB complement component 1, q subcomponent, B chain
CALML5 calmodulin-like 5
CCDC71 coiled-coil domain containing 71
CD160 CD160 molecule
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDK14 cyclin-dependent kinase 14
CDO1 cysteine dioxygenase type 1
CFAP45 cilia and flagella associated protein 45
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLTB clathrin, light chain B
CNN3 calponin 3, acidic
CNTNAP2 contactin associated protein-like 2
COL1A1 collagen, type I, alpha 1
COL5A2 collagen, type V, alpha 2
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
CRYGC crystallin, gamma C
DMPK dystrophia myotonica-protein kinase
ENOX2 ecto-NOX disulfide-thiol exchanger 2
FER1L4 fer-1-like family member 4, pseudogene (functional)
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGF18 fibroblast growth factor 18
FGFR2 fibroblast growth factor receptor 2
FSCN1 fascin actin-bundling protein 1
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GJA8 gap junction protein, alpha 8, 50kDa
GLP1R glucagon-like peptide 1 receptor
GPNMB glycoprotein (transmembrane) nmb
GPRC5D G protein-coupled receptor, class C, group 5, member D
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase
ICOSLG inducible T-cell co-stimulator ligand
IGHM immunoglobulin heavy constant mu
IGLJ3 immunoglobulin lambda joining 3
INHBA inhibin, beta A
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KRT9 keratin 9, type I
LOC79999 uncharacterized LOC79999
LPL lipoprotein lipase
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MAPK7 mitogen-activated protein kinase 7
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MATN3 matrilin 3
MEF2D myocyte enhancer factor 2D
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NR2E3 nuclear receptor subfamily 2, group E, member 3
OPLAH 5-oxoprolinase (ATP-hydrolysing)
OSGIN1 oxidative stress induced growth inhibitor 1
PDE5A phosphodiesterase 5A, cGMP-specific
PEG10 paternally expressed 10
PHF1 PHD finger protein 1
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PLCD1 phospholipase C, delta 1
PVRL3 poliovirus receptor-related 3
RASAL2 RAS protein activator like 2
RERE arginine-glutamic acid dipeptide (RE) repeats
RHBG Rh family, B glycoprotein (gene/pseudogene)
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RSG1 REM2 and RAB-like small GTPase 1
S100A8 S100 calcium binding protein A8
SETBP1 SET binding protein 1
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SMYD2 SET and MYND domain containing 2
SPTBN5 spectrin, beta, non-erythrocytic 5
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
TBC1D2 TBC1 domain family, member 2
TECTA tectorin alpha
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
THOP1 thimet oligopeptidase 1
TMEM45A transmembrane protein 45A
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TSC22D4 TSC22 domain family, member 4
TSPAN9 tetraspanin 9
UBE2I ubiquitin-conjugating enzyme E2I
VNN2 vanin 2
ZBED4 zinc finger, BED-type containing 4
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF112 zinc finger protein 112
ZNF419 zinc finger protein 419
ZSCAN2 zinc finger and SCAN domain containing 2

decreased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ADCY7 adenylate cyclase 7
ADGRG2 adhesion G protein-coupled receptor G2
AGMAT agmatine ureohydrolase (agmatinase)
ALS2CL ALS2 C-terminal like
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
BATF basic leucine zipper transcription factor, ATF-like
BAX BCL2-associated X protein
C11ORF63 chromosome 11 open reading frame 63
C1ORF105 chromosome 1 open reading frame 105
C2ORF27A chromosome 2 open reading frame 27A
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC186 coiled-coil domain containing 186
CCDC6 coiled-coil domain containing 6
CCDC85C coiled-coil domain containing 85C
CCNO cyclin O
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CLDN1 claudin 1
CLEC7A C-type lectin domain family 7, member A
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DEAF1 DEAF1 transcription factor
DSCAM Down syndrome cell adhesion molecule
FAM131A family with sequence similarity 131, member A
FKBP5 FK506 binding protein 5
GJA9 gap junction protein, alpha 9, 59kDa
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR143 G protein-coupled receptor 143
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIRA histone cell cycle regulator
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
IFI6 interferon, alpha-inducible protein 6
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
LOC390998 ribosomal protein L10 pseudogene
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LTBP2 latent transforming growth factor beta binding protein 2
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MED15 mediator complex subunit 15
MEFV Mediterranean fever
METTL16 methyltransferase like 16
MFGE8 milk fat globule-EGF factor 8 protein
MRPS18C mitochondrial ribosomal protein S18C
MTA2 metastasis associated 1 family, member 2
MTCP1 mature T-cell proliferation 1
NCALD neurocalcin delta
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEUROD4 neuronal differentiation 4
NNAT neuronatin
ONECUT1 one cut homeobox 1
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PARD6A par-6 family cell polarity regulator alpha
PCDHGA8 protocadherin gamma subfamily A, 8
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDIA3 protein disulfide isomerase family A, member 3
PHEX phosphate regulating endopeptidase homolog, X-linked
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRSS53 protease, serine, 53
RAI2 retinoic acid induced 2
RNF208 ring finger protein 208
SCD5 stearoyl-CoA desaturase 5
SCGB2A2 secretoglobin, family 2A, member 2
SEC14L2 SEC14-like 2 (S. cerevisiae)
SELL selectin L
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMAD5 SMAD family member 5
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SPRYD7 SPRY domain containing 7
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TCTN2 tectonic family member 2
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TLR5 toll-like receptor 5
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TTLL1 tubulin tyrosine ligase-like family member 1
UPK3B uroplakin 3B
USB1 U6 snRNA biogenesis 1
USP36 ubiquitin specific peptidase 36
VASH2 vasohibin 2
WDR76 WD repeat domain 76
ZNF35 zinc finger protein 35
ZNF423 zinc finger protein 423
ZNF442 zinc finger protein 442
ZNF480 zinc finger protein 480