| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the meclozine-3285 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACPP | acid phosphatase, prostate |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| AMOTL2 | angiomotin like 2 |
| APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ARTN | artemin |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATF3 | activating transcription factor 3 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CCNG2 | cyclin G2 |
| CD52 | CD52 molecule |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CD70 | CD70 molecule |
| CDC25C | cell division cycle 25C |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| COL3A1 | collagen, type III, alpha 1 |
| CORO7 | coronin 7 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DEPDC5 | DEP domain containing 5 |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DUSP10 | dual specificity phosphatase 10 |
| DUSP9 | dual specificity phosphatase 9 |
| EHD1 | EH-domain containing 1 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FANCA | Fanconi anemia, complementation group A |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GAP43 | growth associated protein 43 |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GPR85 | G protein-coupled receptor 85 |
| GTPBP2 | GTP binding protein 2 |
| HOXA10 | homeobox A10 |
| HOXB2 | homeobox B2 |
| HPGDS | hematopoietic prostaglandin D synthase |
| ICAM1 | intercellular adhesion molecule 1 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| INHBE | inhibin, beta E |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KIAA1107 | KIAA1107 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| KLF12 | Kruppel-like factor 12 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| LMTK2 | lemur tyrosine kinase 2 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) |
| MAP1B | microtubule-associated protein 1B |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 |
| MDM4 | MDM4, p53 regulator |
| MR1 | major histocompatibility complex, class I-related |
| NF2 | neurofibromin 2 (merlin) |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PIGR | polymeric immunoglobulin receptor |
| PPM1E | protein phosphatase, Mg2+/Mn2+ dependent, 1E |
| RANBP10 | RAN binding protein 10 |
| RASA3 | RAS p21 protein activator 3 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STX7 | syntaxin 7 |
| TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
| TBL2 | transducin (beta)-like 2 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TM4SF20 | transmembrane 4 L six family member 20 |
| TRIB2 | tribbles pseudokinase 2 |
| TRIB3 | tribbles pseudokinase 3 |
| TRIM29 | tripartite motif containing 29 |
| TSC22D3 | TSC22 domain family, member 3 |
| TSC22D4 | TSC22 domain family, member 4 |
| TSHR | thyroid stimulating hormone receptor |
| TTC38 | tetratricopeptide repeat domain 38 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor |
| VEGFA | vascular endothelial growth factor A |
| VLDLR | very low density lipoprotein receptor |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF609 | zinc finger protein 609 |
| ZNF76 | zinc finger protein 76 |
| ZNF768 | zinc finger protein 768 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ACTL8 | actin-like 8 |
| ACVR2B | activin A receptor, type IIB |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BPGM | 2,3-bisphosphoglycerate mutase |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C5AR2 | complement component 5a receptor 2 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CAPN5 | calpain 5 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CENPQ | centromere protein Q |
| CLIC3 | chloride intracellular channel 3 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CTRL | chymotrypsin-like |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DCAF16 | DDB1 and CUL4 associated factor 16 |
| DIXDC1 | DIX domain containing 1 |
| EFNA3 | ephrin-A3 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ERCC4 | excision repair cross-complementation group 4 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FA2H | fatty acid 2-hydroxylase |
| FAM188A | family with sequence similarity 188, member A |
| FAN1 | FANCD2/FANCI-associated nuclease 1 |
| FBXO31 | F-box protein 31 |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GMPR | guanosine monophosphate reductase |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H4D | histone cluster 1, H4d |
| HIST1H4F | histone cluster 1, H4f |
| HOXC10 | homeobox C10 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 |
| IQCG | IQ motif containing G |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| JMJD4 | jumonji domain containing 4 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LTC4S | leukotriene C4 synthase |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MED18 | mediator complex subunit 18 |
| METTL2B | methyltransferase like 2B |
| MFSD11 | major facilitator superfamily domain containing 11 |
| NIPAL2 | NIPA-like domain containing 2 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPTX1 | neuronal pentraxin I |
| NPY1R | neuropeptide Y receptor Y1 |
| NPY5R | neuropeptide Y receptor Y5 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| OLFML2A | olfactomedin-like 2A |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PCDHB13 | protocadherin beta 13 |
| PDIA3 | protein disulfide isomerase family A, member 3 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PGBD5 | piggyBac transposable element derived 5 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLXNA3 | plexin A3 |
| PROCR | protein C receptor, endothelial |
| PRR14L | proline rich 14-like |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PTK6 | protein tyrosine kinase 6 |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| SCAI | suppressor of cancer cell invasion |
| SECTM1 | secreted and transmembrane 1 |
| SETD1A | SET domain containing 1A |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SPATA2L | spermatogenesis associated 2-like |
| STK4 | serine/threonine kinase 4 |
| STRA6 | stimulated by retinoic acid 6 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TEP1 | telomerase-associated protein 1 |
| TFF2 | trefoil factor 2 |
| TH | tyrosine hydroxylase |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM209 | transmembrane protein 209 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| ULBP2 | UL16 binding protein 2 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| WDR76 | WD repeat domain 76 |
| WFDC2 | WAP four-disulfide core domain 2 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF204P | zinc finger protein 204, pseudogene |
| ZNF652 | zinc finger protein 652 |
| ZNF721 | zinc finger protein 721 |