| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the meclozine-5244 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AMACR | alpha-methylacyl-CoA racemase |
| ANGPT4 | angiopoietin 4 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATF3 | activating transcription factor 3 |
| ATM | ATM serine/threonine kinase |
| BCAM | basal cell adhesion molecule (Lutheran blood group) |
| BGN | biglycan |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CD101 | CD101 molecule |
| CD6 | CD6 molecule |
| CDHR2 | cadherin-related family member 2 |
| CFHR2 | complement factor H-related 2 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLEC4M | C-type lectin domain family 4, member M |
| CLGN | calmegin |
| COL21A1 | collagen, type XXI, alpha 1 |
| CSNK1G1 | casein kinase 1, gamma 1 |
| CTNS | cystinosin, lysosomal cystine transporter |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| DIAPH2-AS1 | DIAPH2 antisense RNA 1 |
| DOK5 | docking protein 5 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EPN1 | epsin 1 |
| FBXO41 | F-box protein 41 |
| FUT3 | fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) |
| GJA4 | gap junction protein, alpha 4, 37kDa |
| GM2A | GM2 ganglioside activator |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| GPR137 | G protein-coupled receptor 137 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 |
| HCN4 | hyperpolarization activated cyclic nucleotide gated potassium channel 4 |
| IHH | indian hedgehog |
| INHBE | inhibin, beta E |
| IRAK3 | interleukin-1 receptor-associated kinase 3 |
| IRS2 | insulin receptor substrate 2 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| KLHL3 | kelch-like family member 3 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| KRT16 | keratin 16, type I |
| LARP7 | La ribonucleoprotein domain family, member 7 |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LOXL3 | lysyl oxidase-like 3 |
| LPL | lipoprotein lipase |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MARK2 | MAP/microtubule affinity-regulating kinase 2 |
| MOBP | myelin-associated oligodendrocyte basic protein |
| MUC3B | mucin 3B, cell surface associated |
| MYOZ1 | myozenin 1 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NPY | neuropeptide Y |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PCDH11Y | protocadherin 11 Y-linked |
| PCDH9 | protocadherin 9 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLCD1 | phospholipase C, delta 1 |
| PLK3 | polo-like kinase 3 |
| PNMAL1 | paraneoplastic Ma antigen family-like 1 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PPP1R2P9 | protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRPH2 | peripherin 2 (retinal degeneration, slow) |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) |
| RPL35A | ribosomal protein L35a |
| RUNDC3B | RUN domain containing 3B |
| RUNX1 | runt-related transcription factor 1 |
| SDC3 | syndecan 3 |
| SERPINF2 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa |
| STS | steroid sulfatase (microsomal), isozyme S |
| TBC1D22A | TBC1 domain family, member 22A |
| TBCD | tubulin folding cofactor D |
| TM4SF20 | transmembrane 4 L six family member 20 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TREX1 | three prime repair exonuclease 1 |
| TRIM38 | tripartite motif containing 38 |
| TRPC4 | transient receptor potential cation channel, subfamily C, member 4 |
| TSC22D3 | TSC22 domain family, member 3 |
| UBE2H | ubiquitin-conjugating enzyme E2H |
| UNC119 | unc-119 homolog (C. elegans) |
| VEGFA | vascular endothelial growth factor A |
| ZSCAN18 | zinc finger and SCAN domain containing 18 |
| ZXDB | zinc finger, X-linked, duplicated B |
| Symbol | Name |
|---|---|
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| ADCY7 | adenylate cyclase 7 |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARMC6 | armadillo repeat containing 6 |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BCL9 | B-cell CLL/lymphoma 9 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CAPN15 | calpain 15 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CBX8 | chromobox homolog 8 |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CEP85 | centrosomal protein 85kDa |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DVL1 | dishevelled segment polarity protein 1 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EFNA3 | ephrin-A3 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| FAM155B | family with sequence similarity 155, member B |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FBXO31 | F-box protein 31 |
| FIG4 | FIG4 phosphoinositide 5-phosphatase |
| FOSL1 | FOS-like antigen 1 |
| FRMD1 | FERM domain containing 1 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GPX2 | glutathione peroxidase 2 |
| GRB7 | growth factor receptor-bound protein 7 |
| HDAC11 | histone deacetylase 11 |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HOXC10 | homeobox C10 |
| HOXC8 | homeobox C8 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IL4R | interleukin 4 receptor |
| INPP1 | inositol polyphosphate-1-phosphatase |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| IRF9 | interferon regulatory factor 9 |
| KIAA0319L | KIAA0319-like |
| KLC2 | kinesin light chain 2 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LMNB1 | lamin B1 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MEFV | Mediterranean fever |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MTA2 | metastasis associated 1 family, member 2 |
| MUC3A | mucin 3A, cell surface associated |
| MVP | major vault protein |
| MYO1E | myosin IE |
| NCALD | neurocalcin delta |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NXPH4 | neurexophilin 4 |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| PGBD5 | piggyBac transposable element derived 5 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PIPOX | pipecolic acid oxidase |
| PODXL2 | podocalyxin-like 2 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRSS53 | protease, serine, 53 |
| PTPN9 | protein tyrosine phosphatase, non-receptor type 9 |
| RAB30 | RAB30, member RAS oncogene family |
| RAB3A | RAB3A, member RAS oncogene family |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
| RFPL3 | ret finger protein-like 3 |
| RPGRIP1L | RPGRIP1-like |
| S100A7 | S100 calcium binding protein A7 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| STRA6 | stimulated by retinoic acid 6 |
| TMEM104 | transmembrane protein 104 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TSPAN5 | tetraspanin 5 |
| TUBA3C | tubulin, alpha 3c |
| TWISTNB | TWIST neighbor |
| VASH1 | vasohibin 1 |
| VPS9D1 | VPS9 domain containing 1 |
| XYLT1 | xylosyltransferase I |
| XYLT2 | xylosyltransferase II |
| YBX2 | Y box binding protein 2 |
| ZFHX4 | zinc finger homeobox 4 |
| ZMYM3 | zinc finger, MYM-type 3 |
| ZNF574 | zinc finger protein 574 |
| ZNF747 | zinc finger protein 747 |
