medrysone-3403 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the medrysone-3403 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAA2 acetyl-CoA acyltransferase 2
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
BIN1 bridging integrator 1
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD70 CD70 molecule
CDC14A cell division cycle 14A
CES2 carboxylesterase 2
CLCN7 chloride channel, voltage-sensitive 7
CLTA clathrin, light chain A
COL13A1 collagen, type XIII, alpha 1
CRTC1 CREB regulated transcription coactivator 1
CSF1 colony stimulating factor 1 (macrophage)
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
ECE1 endothelin converting enzyme 1
EFNB3 ephrin-B3
ELSPBP1 epididymal sperm binding protein 1
EPOR erythropoietin receptor
EXTL1 exostosin-like glycosyltransferase 1
FAM204A family with sequence similarity 204, member A
FDPS farnesyl diphosphate synthase
FH fumarate hydratase
FKBP8 FK506 binding protein 8, 38kDa
FLJ11292
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GFER growth factor, augmenter of liver regeneration
GJB3 gap junction protein, beta 3, 31kDa
GK3P glycerol kinase 3 pseudogene
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GPATCH4 G patch domain containing 4
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GSAP gamma-secretase activating protein
HEXIM1 hexamethylene bis-acetamide inducible 1
HFE hemochromatosis
HHAT hedgehog acyltransferase
HIPK2 homeodomain interacting protein kinase 2
ICAM1 intercellular adhesion molecule 1
IGHA1 immunoglobulin heavy constant alpha 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIF13B kinesin family member 13B
KLF7 Kruppel-like factor 7 (ubiquitous)
KRT19P2 keratin 19 pseudogene 2
LARP7 La ribonucleoprotein domain family, member 7
LHX6 LIM homeobox 6
LMAN1 lectin, mannose-binding, 1
LMNA lamin A/C
LOC100286895 cell division cycle 27 homolog pseudogene
LPCAT4 lysophosphatidylcholine acyltransferase 4
LPXN leupaxin
LUZP1 leucine zipper protein 1
LY6G6C lymphocyte antigen 6 complex, locus G6C
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MDM4 MDM4, p53 regulator
MIA3 melanoma inhibitory activity family, member 3
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OSGIN2 oxidative stress induced growth inhibitor family member 2
PACS1 phosphofurin acidic cluster sorting protein 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCSK6 proprotein convertase subtilisin/kexin type 6
PHEX phosphate regulating endopeptidase homolog, X-linked
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
POLM polymerase (DNA directed), mu
PRDM2 PR domain containing 2, with ZNF domain
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RAB3A RAB3A, member RAS oncogene family
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RNF39 ring finger protein 39
SCN1B sodium channel, voltage gated, type I beta subunit
SEC14L2 SEC14-like 2 (S. cerevisiae)
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SHANK2 SH3 and multiple ankyrin repeat domains 2
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC35E2 solute carrier family 35, member E2
STON1 stonin 1
SUGP1 SURP and G patch domain containing 1
TAT tyrosine aminotransferase
TDRKH tudor and KH domain containing
TEF thyrotrophic embryonic factor
TK2 thymidine kinase 2, mitochondrial
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TM4SF1 transmembrane 4 L six family member 1
TP53I11 tumor protein p53 inducible protein 11
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VAMP5 vesicle-associated membrane protein 5
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
WNT6 wingless-type MMTV integration site family, member 6
ZBTB1 zinc finger and BTB domain containing 1
ZNF440 zinc finger protein 440
ZSCAN12 zinc finger and SCAN domain containing 12

decreased expression

Symbol Name
ANKRD40 ankyrin repeat domain 40
ASB8 ankyrin repeat and SOCS box containing 8
ATG9A autophagy related 9A
BBC3 BCL2 binding component 3
BBS7 Bardet-Biedl syndrome 7
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C19ORF40 chromosome 19 open reading frame 40
C2ORF44 chromosome 2 open reading frame 44
C4ORF29 chromosome 4 open reading frame 29
C5ORF30 chromosome 5 open reading frame 30
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CASD1 CAS1 domain containing 1
CCDC109B coiled-coil domain containing 109B
CEP97 centrosomal protein 97kDa
CHKB choline kinase beta
CHST10 carbohydrate sulfotransferase 10
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CIT citron rho-interacting serine/threonine kinase
CLDN9 claudin 9
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
DCP1A decapping mRNA 1A
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHRS3 dehydrogenase/reductase (SDR family) member 3
DVL1 dishevelled segment polarity protein 1
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPHA2 EPH receptor A2
EPPK1 epiplakin 1
EVPL envoplakin
F3 coagulation factor III (thromboplastin, tissue factor)
FBXW12 F-box and WD repeat domain containing 12
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FKBPL FK506 binding protein like
FZD3 frizzled class receptor 3
FZD6 frizzled class receptor 6
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLS2 glutaminase 2 (liver, mitochondrial)
GRAMD3 GRAM domain containing 3
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GTF2I general transcription factor IIi
GUSBP3 glucuronidase, beta pseudogene 3
HAUS6 HAUS augmin-like complex, subunit 6
HIRA histone cell cycle regulator
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
ICK intestinal cell (MAK-like) kinase
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
JUNB jun B proto-oncogene
KCTD15 potassium channel tetramerization domain containing 15
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRRC49 leucine rich repeat containing 49
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAPKBP1 mitogen-activated protein kinase binding protein 1
MOSPD3 motile sperm domain containing 3
MSL2 male-specific lethal 2 homolog (Drosophila)
NDRG4 NDRG family member 4
NFS1 NFS1 cysteine desulfurase
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PTDSS2 phosphatidylserine synthase 2
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RAB5B RAB5B, member RAS oncogene family
RAD54L RAD54-like (S. cerevisiae)
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RBL1 retinoblastoma-like 1
RFWD3 ring finger and WD repeat domain 3
RIBC2 RIB43A domain with coiled-coils 2
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF146 ring finger protein 146
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SAV1 salvador family WW domain containing protein 1
SH2B3 SH2B adaptor protein 3
SIDT1 SID1 transmembrane family, member 1
SLC16A6 solute carrier family 16, member 6
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SPAG1 sperm associated antigen 1
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TIPRL TOR signaling pathway regulator
TMEM2 transmembrane protein 2
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TSPAN15 tetraspanin 15
TUBG2 tubulin, gamma 2
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
WBP2 WW domain binding protein 2
WDR76 WD repeat domain 76
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZBTB3 zinc finger and BTB domain containing 3
ZNF652 zinc finger protein 652
ZNF721 zinc finger protein 721
ZNF74 zinc finger protein 74