| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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199 genes differentially expressed following the medrysone-3705 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACE2 | angiotensin I converting enzyme 2 |
| ADAP1 | ArfGAP with dual PH domains 1 |
| ADGRD2 | adhesion G protein-coupled receptor D2 |
| ADRA1A | adrenoceptor alpha 1A |
| ADRB3 | adrenoceptor beta 3 |
| ANGPTL4 | angiopoietin-like 4 |
| AQP4 | aquaporin 4 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial |
| BMP2 | bone morphogenetic protein 2 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| C11ORF16 | chromosome 11 open reading frame 16 |
| C4BPA | complement component 4 binding protein, alpha |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CCR9 | chemokine (C-C motif) receptor 9 |
| CHAT | choline O-acetyltransferase |
| CKMT2 | creatine kinase, mitochondrial 2 (sarcomeric) |
| CLDN18 | claudin 18 |
| CLEC1A | C-type lectin domain family 1, member A |
| CLMN | calmin (calponin-like, transmembrane) |
| CNTD2 | cyclin N-terminal domain containing 2 |
| DMBT1 | deleted in malignant brain tumors 1 |
| DUSP1 | dual specificity phosphatase 1 |
| EGR1 | early growth response 1 |
| EIF3F | eukaryotic translation initiation factor 3, subunit F |
| EPS15L1 | epidermal growth factor receptor pathway substrate 15-like 1 |
| ESR1 | estrogen receptor 1 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FBXL18 | F-box and leucine-rich repeat protein 18 |
| FBXO4 | F-box protein 4 |
| FOXO4 | forkhead box O4 |
| FUT2 | fucosyltransferase 2 (secretor status included) |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| HCN4 | hyperpolarization activated cyclic nucleotide gated potassium channel 4 |
| HCRTR2 | hypocretin (orexin) receptor 2 |
| HHAT | hedgehog acyltransferase |
| HIST1H2AL | histone cluster 1, H2al |
| ICAM5 | intercellular adhesion molecule 5, telencephalin |
| IGL | immunoglobulin lambda locus |
| IL12RB2 | interleukin 12 receptor, beta 2 |
| IL36G | interleukin 36, gamma |
| INO80D | INO80 complex subunit D |
| IPCEF1 | interaction protein for cytohesin exchange factors 1 |
| JADE2 | jade family PHD finger 2 |
| KIF21B | kinesin family member 21B |
| KLK10 | kallikrein-related peptidase 10 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MEF2D | myocyte enhancer factor 2D |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MORN1 | MORN repeat containing 1 |
| MTMR8 | myotubularin related protein 8 |
| NCALD | neurocalcin delta |
| NMRK2 | nicotinamide riboside kinase 2 |
| NNMT | nicotinamide N-methyltransferase |
| NPY6R | neuropeptide Y receptor Y6 (pseudogene) |
| NRF1 | nuclear respiratory factor 1 |
| NRP2 | neuropilin 2 |
| OPCML | opioid binding protein/cell adhesion molecule-like |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PDLIM4 | PDZ and LIM domain 4 |
| PIP | prolactin-induced protein |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| PLK3 | polo-like kinase 3 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRDM2 | PR domain containing 2, with ZNF domain |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| PSORS1C1 | psoriasis susceptibility 1 candidate 1 |
| PTCRA | pre T-cell antigen receptor alpha |
| PTPRJ | protein tyrosine phosphatase, receptor type, J |
| RAB40C | RAB40C, member RAS oncogene family |
| RASL11B | RAS-like, family 11, member B |
| REEP1 | receptor accessory protein 1 |
| RHAG | Rh-associated glycoprotein |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
| SFTPB | surfactant protein B |
| SH2D3C | SH2 domain containing 3C |
| SKIL | SKI-like proto-oncogene |
| SLC30A5 | solute carrier family 30 (zinc transporter), member 5 |
| SLC39A2 | solute carrier family 39 (zinc transporter), member 2 |
| SOSTDC1 | sclerostin domain containing 1 |
| SOX2 | SRY (sex determining region Y)-box 2 |
| STAB2 | stabilin 2 |
| STRA6 | stimulated by retinoic acid 6 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| SYT11 | synaptotagmin XI |
| TACC1 | transforming, acidic coiled-coil containing protein 1 |
| TAOK2 | TAO kinase 2 |
| TBCD | tubulin folding cofactor D |
| TMPRSS6 | transmembrane protease, serine 6 |
| TTC12 | tetratricopeptide repeat domain 12 |
| WNT3 | wingless-type MMTV integration site family, member 3 |
| ZIC3 | Zic family member 3 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| AGO4 | argonaute RISC catalytic component 4 |
| AK5 | adenylate kinase 5 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| ANXA2P1 | annexin A2 pseudogene 1 |
| APH1B | APH1B gamma secretase subunit |
| ARSB | arylsulfatase B |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BFSP1 | beaded filament structural protein 1, filensin |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CDH19 | cadherin 19, type 2 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHRDL1 | chordin-like 1 |
| CLDN14 | claudin 14 |
| CLSTN3 | calsyntenin 3 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 |
| CYBRD1 | cytochrome b reductase 1 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DENND4A | DENN/MADD domain containing 4A |
| ESM1 | endothelial cell-specific molecule 1 |
| EXOC5 | exocyst complex component 5 |
| GALK1 | galactokinase 1 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HDAC9 | histone deacetylase 9 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| HSF2 | heat shock transcription factor 2 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFT54 | intraflagellar transport 54 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KIAA0513 | KIAA0513 |
| KIAA1107 | KIAA1107 |
| KIAA1549L | KIAA1549-like |
| KLF3 | Kruppel-like factor 3 (basic) |
| KRT34 | keratin 34, type I |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LPAR6 | lysophosphatidic acid receptor 6 |
| LY96 | lymphocyte antigen 96 |
| MAP3K7CL | MAP3K7 C-terminal like |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MCOLN3 | mucolipin 3 |
| MEX3C | mex-3 RNA binding family member C |
| MX1 | MX dynamin-like GTPase 1 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| OCLN | occludin |
| OGDHL | oxoglutarate dehydrogenase-like |
| OSMR | oncostatin M receptor |
| P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit |
| PEX13 | peroxisomal biogenesis factor 13 |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PLAU | plasminogen activator, urokinase |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H |
| QSER1 | glutamine and serine rich 1 |
| RAB3A | RAB3A, member RAS oncogene family |
| RGS19 | regulator of G-protein signaling 19 |
| RRAGB | Ras-related GTP binding B |
| RUSC2 | RUN and SH3 domain containing 2 |
| RWDD2A | RWD domain containing 2A |
| S100A3 | S100 calcium binding protein A3 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SDC3 | syndecan 3 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SH3GLB2 | SH3-domain GRB2-like endophilin B2 |
| SLC9A7 | solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 |
| SPIDR | scaffolding protein involved in DNA repair |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| TAGLN3 | transgelin 3 |
| TBC1D17 | TBC1 domain family, member 17 |
| TMEM2 | transmembrane protein 2 |
| TMEM209 | transmembrane protein 209 |
| TMEM40 | transmembrane protein 40 |
| TMEM53 | transmembrane protein 53 |
| TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| UBQLN4 | ubiquilin 4 |
| UGT8 | UDP glycosyltransferase 8 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| ZNF180 | zinc finger protein 180 |
| ZNF254 | zinc finger protein 254 |
| ZNF286A | zinc finger protein 286A |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF675 | zinc finger protein 675 |
| ZNF702P | zinc finger protein 702, pseudogene |
| ZNF747 | zinc finger protein 747 |
| ZW10 | zw10 kinetochore protein |