medrysone-4266 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the medrysone-4266 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADGRA2 adhesion G protein-coupled receptor A2
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide
AIM2 absent in melanoma 2
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALDOB aldolase B, fructose-bisphosphate
ARHGAP44 Rho GTPase activating protein 44
ATAT1 alpha tubulin acetyltransferase 1
ATN1 atrophin 1
ATP11A ATPase, class VI, type 11A
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3
BBC3 BCL2 binding component 3
BTF3P11 basic transcription factor 3 pseudogene 11
C14ORF1 chromosome 14 open reading frame 1
C7ORF69 chromosome 7 open reading frame 69
CALML3 calmodulin-like 3
CD6 CD6 molecule
CDHR2 cadherin-related family member 2
CDK13 cyclin-dependent kinase 13
CDRT1 CMT1A duplicated region transcript 1
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CES1 carboxylesterase 1
CHRNG cholinergic receptor, nicotinic, gamma (muscle)
CMA1 chymase 1, mast cell
CNGB3 cyclic nucleotide gated channel beta 3
COL14A1 collagen, type XIV, alpha 1
COL8A1 collagen, type VIII, alpha 1
DAAM2 dishevelled associated activator of morphogenesis 2
DESI2 desumoylating isopeptidase 2
DMC1 DNA meiotic recombinase 1
DPF1 D4, zinc and double PHD fingers family 1
ENPEP glutamyl aminopeptidase (aminopeptidase A)
ERN2 endoplasmic reticulum to nucleus signaling 2
ESR1 estrogen receptor 1
FILIP1L filamin A interacting protein 1-like
FLI1 Fli-1 proto-oncogene, ETS transcription factor
GATA2 GATA binding protein 2
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GP2 glycoprotein 2 (zymogen granule membrane)
GREB1L growth regulation by estrogen in breast cancer-like
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
ICOSLG inducible T-cell co-stimulator ligand
IL2 interleukin 2
IRX4 iroquois homeobox 4
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KIDINS220 kinase D-interacting substrate, 220kDa
KIF21B kinesin family member 21B
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
KMT2A lysine (K)-specific methyltransferase 2A
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LRP1 low density lipoprotein receptor-related protein 1
LY6D lymphocyte antigen 6 complex, locus D
MAPRE3 microtubule-associated protein, RP/EB family, member 3
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MEGF8 multiple EGF-like-domains 8
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
NAG18 NAG18 mRNA
NDRG2 NDRG family member 2
NEFM neurofilament, medium polypeptide
NPY5R neuropeptide Y receptor Y5
OR10J1 olfactory receptor, family 10, subfamily J, member 1
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OXCT2 3-oxoacid CoA transferase 2
PAX2 paired box 2
PCSK6 proprotein convertase subtilisin/kexin type 6
PDLIM3 PDZ and LIM domain 3
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PRM1 protamine 1
PRUNE2 prune homolog 2 (Drosophila)
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PXN paxillin
RAB6A RAB6A, member RAS oncogene family
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RPL7 ribosomal protein L7
RUNX1 runt-related transcription factor 1
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SFTPB surfactant protein B
SLAMF7 SLAM family member 7
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SPAG8 sperm associated antigen 8
SPN sialophorin
SYT13 synaptotagmin XIII
TBX10 T-box 10
TBX6 T-box 6
TK2 thymidine kinase 2, mitochondrial
TLDC1 TBC/LysM-associated domain containing 1
TLR4 toll-like receptor 4
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNS4 tensin 4
TRIM15 tripartite motif containing 15
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae)
TTC22 tetratricopeptide repeat domain 22
UPK2 uroplakin 2
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
ZMYND8 zinc finger, MYND-type containing 8
ZNF440 zinc finger protein 440

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AEN apoptosis enhancing nuclease
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ANAPC10 anaphase promoting complex subunit 10
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ATAD5 ATPase family, AAA domain containing 5
BCL2A1 BCL2-related protein A1
BEX1 brain expressed, X-linked 1
C16ORF59 chromosome 16 open reading frame 59
C5 complement component 5
CADPS2 Ca++-dependent secretion activator 2
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CCDC88C coiled-coil domain containing 88C
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CFD complement factor D (adipsin)
CLDN4 claudin 4
CLSPN claspin
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family)
CRIP1 cysteine-rich protein 1 (intestinal)
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTNNBL1 catenin, beta like 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DCBLD2 discoidin, CUB and LCCL domain containing 2
DTWD1 DTW domain containing 1
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EDIL3 EGF-like repeats and discoidin I-like domains 3
EFNA3 ephrin-A3
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GCHFR GTP cyclohydrolase I feedback regulator
GNPDA1 glucosamine-6-phosphate deaminase 1
GUSBP3 glucuronidase, beta pseudogene 3
H2AFJ H2A histone family, member J
HAUS6 HAUS augmin-like complex, subunit 6
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST1H2BH histone cluster 1, H2bh
HIST1H4C histone cluster 1, H4c
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
IER3IP1 immediate early response 3 interacting protein 1
IFI6 interferon, alpha-inducible protein 6
IGSF3 immunoglobulin superfamily, member 3
IL7R interleukin 7 receptor
INF2 inverted formin, FH2 and WH2 domain containing
KIAA1107 KIAA1107
KIF3A kinesin family member 3A
KRT15 keratin 15, type I
LINC00597 long intergenic non-protein coding RNA 597
MED4 mediator complex subunit 4
MFSD6 major facilitator superfamily domain containing 6
MIS12 MIS12 kinetochore complex component
MMP1 matrix metallopeptidase 1
NABP1 nucleic acid binding protein 1
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NOL10 nucleolar protein 10
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PBLD phenazine biosynthesis-like protein domain containing
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PERP PERP, TP53 apoptosis effector
PMCH pro-melanin-concentrating hormone
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PTX3 pentraxin 3, long
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPS14P3 ribosomal protein S14 pseudogene 3
SEC61B Sec61 beta subunit
SERINC5 serine incorporator 5
SFT2D2 SFT2 domain containing 2
SLC46A3 solute carrier family 46, member 3
SMAD5 SMAD family member 5
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SPIN1 spindlin 1
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STK16 serine/threonine kinase 16
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TM6SF1 transmembrane 6 superfamily member 1
TMEM159 transmembrane protein 159
TMEM2 transmembrane protein 2
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSPAN8 tetraspanin 8
TWISTNB TWIST neighbor
UNC119 unc-119 homolog (C. elegans)
USB1 U6 snRNA biogenesis 1
WDR25 WD repeat domain 25
WNT10B wingless-type MMTV integration site family, member 10B
WWC2 WW and C2 domain containing 2
YEATS4 YEATS domain containing 4
ZBED1 zinc finger, BED-type containing 1
ZC3H4 zinc finger CCCH-type containing 4
ZNF350 zinc finger protein 350
ZNF768 zinc finger protein 768
ZNF770 zinc finger protein 770
ZNF778 zinc finger protein 778