| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the medrysone-4266 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) |
| ACSBG1 | acyl-CoA synthetase bubblegum family member 1 |
| ADGRA2 | adhesion G protein-coupled receptor A2 |
| ADH1A | alcohol dehydrogenase 1A (class I), alpha polypeptide |
| AIM2 | absent in melanoma 2 |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ARHGAP44 | Rho GTPase activating protein 44 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATN1 | atrophin 1 |
| ATP11A | ATPase, class VI, type 11A |
| ATP2B3 | ATPase, Ca++ transporting, plasma membrane 3 |
| BBC3 | BCL2 binding component 3 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C14ORF1 | chromosome 14 open reading frame 1 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CALML3 | calmodulin-like 3 |
| CD6 | CD6 molecule |
| CDHR2 | cadherin-related family member 2 |
| CDK13 | cyclin-dependent kinase 13 |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CES1 | carboxylesterase 1 |
| CHRNG | cholinergic receptor, nicotinic, gamma (muscle) |
| CMA1 | chymase 1, mast cell |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| COL14A1 | collagen, type XIV, alpha 1 |
| COL8A1 | collagen, type VIII, alpha 1 |
| DAAM2 | dishevelled associated activator of morphogenesis 2 |
| DESI2 | desumoylating isopeptidase 2 |
| DMC1 | DNA meiotic recombinase 1 |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ESR1 | estrogen receptor 1 |
| FILIP1L | filamin A interacting protein 1-like |
| FLI1 | Fli-1 proto-oncogene, ETS transcription factor |
| GATA2 | GATA binding protein 2 |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GP2 | glycoprotein 2 (zymogen granule membrane) |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| HTR5A | 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IL2 | interleukin 2 |
| IRX4 | iroquois homeobox 4 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KIDINS220 | kinase D-interacting substrate, 220kDa |
| KIF21B | kinesin family member 21B |
| KIR3DS1 | killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LRP1 | low density lipoprotein receptor-related protein 1 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MEGF8 | multiple EGF-like-domains 8 |
| MFI2 | antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 |
| NAG18 | NAG18 mRNA |
| NDRG2 | NDRG family member 2 |
| NEFM | neurofilament, medium polypeptide |
| NPY5R | neuropeptide Y receptor Y5 |
| OR10J1 | olfactory receptor, family 10, subfamily J, member 1 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PAX2 | paired box 2 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDLIM3 | PDZ and LIM domain 3 |
| PIK3R4 | phosphoinositide-3-kinase, regulatory subunit 4 |
| PRM1 | protamine 1 |
| PRUNE2 | prune homolog 2 (Drosophila) |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PXN | paxillin |
| RAB6A | RAB6A, member RAS oncogene family |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RPL7 | ribosomal protein L7 |
| RUNX1 | runt-related transcription factor 1 |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G |
| SFTPB | surfactant protein B |
| SLAMF7 | SLAM family member 7 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SPAG8 | sperm associated antigen 8 |
| SPN | sialophorin |
| SYT13 | synaptotagmin XIII |
| TBX10 | T-box 10 |
| TBX6 | T-box 6 |
| TK2 | thymidine kinase 2, mitochondrial |
| TLDC1 | TBC/LysM-associated domain containing 1 |
| TLR4 | toll-like receptor 4 |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 |
| TNS4 | tensin 4 |
| TRIM15 | tripartite motif containing 15 |
| TRMT1 | tRNA methyltransferase 1 homolog (S. cerevisiae) |
| TTC22 | tetratricopeptide repeat domain 22 |
| UPK2 | uroplakin 2 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked |
| ZMYND8 | zinc finger, MYND-type containing 8 |
| ZNF440 | zinc finger protein 440 |
| Symbol | Name |
|---|---|
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| AEN | apoptosis enhancing nuclease |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ANAPC10 | anaphase promoting complex subunit 10 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BCL2A1 | BCL2-related protein A1 |
| BEX1 | brain expressed, X-linked 1 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C5 | complement component 5 |
| CADPS2 | Ca++-dependent secretion activator 2 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa |
| CCDC88C | coiled-coil domain containing 88C |
| CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase |
| CFD | complement factor D (adipsin) |
| CLDN4 | claudin 4 |
| CLSPN | claspin |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CTNNBL1 | catenin, beta like 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 |
| DTWD1 | DTW domain containing 1 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| EFNA3 | ephrin-A3 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GCHFR | GTP cyclohydrolase I feedback regulator |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| H2AFJ | H2A histone family, member J |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2BH | histone cluster 1, H2bh |
| HIST1H4C | histone cluster 1, H4c |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| IER3IP1 | immediate early response 3 interacting protein 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IGSF3 | immunoglobulin superfamily, member 3 |
| IL7R | interleukin 7 receptor |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| KIAA1107 | KIAA1107 |
| KIF3A | kinesin family member 3A |
| KRT15 | keratin 15, type I |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| MED4 | mediator complex subunit 4 |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MIS12 | MIS12 kinetochore complex component |
| MMP1 | matrix metallopeptidase 1 |
| NABP1 | nucleic acid binding protein 1 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) |
| NOL10 | nucleolar protein 10 |
| NUDT1 | nudix (nucleoside diphosphate linked moiety X)-type motif 1 |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PBLD | phenazine biosynthesis-like protein domain containing |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PERP | PERP, TP53 apoptosis effector |
| PMCH | pro-melanin-concentrating hormone |
| POLR2J2 | polymerase (RNA) II (DNA directed) polypeptide J2 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PTX3 | pentraxin 3, long |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| RPS14P3 | ribosomal protein S14 pseudogene 3 |
| SEC61B | Sec61 beta subunit |
| SERINC5 | serine incorporator 5 |
| SFT2D2 | SFT2 domain containing 2 |
| SLC46A3 | solute carrier family 46, member 3 |
| SMAD5 | SMAD family member 5 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SPIN1 | spindlin 1 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STK16 | serine/threonine kinase 16 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TMEM159 | transmembrane protein 159 |
| TMEM2 | transmembrane protein 2 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TSPAN8 | tetraspanin 8 |
| TWISTNB | TWIST neighbor |
| UNC119 | unc-119 homolog (C. elegans) |
| USB1 | U6 snRNA biogenesis 1 |
| WDR25 | WD repeat domain 25 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| WWC2 | WW and C2 domain containing 2 |
| YEATS4 | YEATS domain containing 4 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZC3H4 | zinc finger CCCH-type containing 4 |
| ZNF350 | zinc finger protein 350 |
| ZNF768 | zinc finger protein 768 |
| ZNF770 | zinc finger protein 770 |
| ZNF778 | zinc finger protein 778 |