medrysone-4727 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the medrysone-4727 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADAM12 ADAM metallopeptidase domain 12
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
ADORA1 adenosine A1 receptor
ARHGAP26 Rho GTPase activating protein 26
ARRB1 arrestin, beta 1
ASIC1 acid sensing (proton gated) ion channel 1
BIRC3 baculoviral IAP repeat containing 3
C9ORF9 chromosome 9 open reading frame 9
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CALML5 calmodulin-like 5
CAMK1D calcium/calmodulin-dependent protein kinase ID
CARD10 caspase recruitment domain family, member 10
CCDC71 coiled-coil domain containing 71
CD209 CD209 molecule
CD22 CD22 molecule
CDC42 cell division cycle 42
CDRT1 CMT1A duplicated region transcript 1
CLEC2B C-type lectin domain family 2, member B
CNKSR2 connector enhancer of kinase suppressor of Ras 2
COL1A1 collagen, type I, alpha 1
COMT catechol-O-methyltransferase
CPNE7 copine VII
CSF1 colony stimulating factor 1 (macrophage)
CYLD cylindromatosis (turban tumor syndrome)
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DFNA5 deafness, autosomal dominant 5
DGKA diacylglycerol kinase, alpha 80kDa
DMRT1 doublesex and mab-3 related transcription factor 1
DUSP6 dual specificity phosphatase 6
EMID1 EMI domain containing 1
EMP1 epithelial membrane protein 1
EPB41L1 erythrocyte membrane protein band 4.1-like 1
EPHA5 EPH receptor A5
ESR1 estrogen receptor 1
ETV4 ets variant 4
FSCN1 fascin actin-bundling protein 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
GPR85 G protein-coupled receptor 85
GRB10 growth factor receptor-bound protein 10
GRM7 glutamate receptor, metabotropic 7
GSK3A glycogen synthase kinase 3 alpha
HDAC7 histone deacetylase 7
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ITGB6 integrin, beta 6
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNK12 potassium channel, two pore domain subfamily K, member 12
KLF9 Kruppel-like factor 9
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAPK7 mitogen-activated protein kinase 7
MAPT microtubule-associated protein tau
MBD2 methyl-CpG binding domain protein 2
MINK1 misshapen-like kinase 1
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MUC3A mucin 3A, cell surface associated
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
OPCML opioid binding protein/cell adhesion molecule-like
PAX8 paired box 8
PCDH1 protocadherin 1
PDE4DIP phosphodiesterase 4D interacting protein
PDE9A phosphodiesterase 9A
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PSCA prostate stem cell antigen
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PURA purine-rich element binding protein A
PURG purine-rich element binding protein G
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
RBM19 RNA binding motif protein 19
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RIMS3 regulating synaptic membrane exocytosis 3
RND1 Rho family GTPase 1
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
SATB2 SATB homeobox 2
SCN10A sodium channel, voltage gated, type X alpha subunit
SERHL2 serine hydrolase-like 2
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3
SLMO1 slowmo homolog 1 (Drosophila)
SNED1 sushi, nidogen and EGF-like domains 1
SPTBN5 spectrin, beta, non-erythrocytic 5
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SYT12 synaptotagmin XII
TACSTD2 tumor-associated calcium signal transducer 2
TAT tyrosine aminotransferase
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TFEB transcription factor EB
TMEM158 transmembrane protein 158 (gene/pseudogene)
VWA5A von Willebrand factor A domain containing 5A
ZG16 zymogen granule protein 16
ZNF440 zinc finger protein 440
ZNF76 zinc finger protein 76
ZNF771 zinc finger protein 771

decreased expression

Symbol Name
ADM adrenomedullin
AFAP1 actin filament associated protein 1
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BGLAP bone gamma-carboxyglutamate (gla) protein
C19ORF73 chromosome 19 open reading frame 73
C1QTNF3 C1q and tumor necrosis factor related protein 3
C7ORF43 chromosome 7 open reading frame 43
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CCDC121 coiled-coil domain containing 121
CCDC85C coiled-coil domain containing 85C
CLSPN claspin
CNGB3 cyclic nucleotide gated channel beta 3
CSF1R colony stimulating factor 1 receptor
CUZD1 CUB and zona pellucida-like domains 1
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DMTN dematin actin binding protein
DPY19L1P1 DPY19L1 pseudogene 1
EFNA3 ephrin-A3
ELP6 elongator acetyltransferase complex subunit 6
FILIP1L filamin A interacting protein 1-like
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GBP2 guanylate binding protein 2, interferon-inducible
GLRA1 glycine receptor, alpha 1
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GRAMD1C GRAM domain containing 1C
GRTP1 growth hormone regulated TBC protein 1
GSTCD glutathione S-transferase, C-terminal domain containing
HAMP hepcidin antimicrobial peptide
HIRA histone cell cycle regulator
HIST1H4D histone cluster 1, H4d
HMOX1 heme oxygenase 1
HOXC10 homeobox C10
IFI6 interferon, alpha-inducible protein 6
KDM8 lysine (K)-specific demethylase 8
LIN7A lin-7 homolog A (C. elegans)
LMO2 LIM domain only 2 (rhombotin-like 1)
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MBNL3 muscleblind-like splicing regulator 3
MITF microphthalmia-associated transcription factor
MMP9 matrix metallopeptidase 9
MRPS18C mitochondrial ribosomal protein S18C
NACA2 nascent polypeptide-associated complex alpha subunit 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NKX3-2 NK3 homeobox 2
NPY1R neuropeptide Y receptor Y1
OLFML2A olfactomedin-like 2A
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PACS1 phosphofurin acidic cluster sorting protein 1
PCDHA5 protocadherin alpha 5
PCDHB13 protocadherin beta 13
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PGR progesterone receptor
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
POLM polymerase (DNA directed), mu
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRF1 perforin 1 (pore forming protein)
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
RAB3D RAB3D, member RAS oncogene family
RFXAP regulatory factor X-associated protein
RUNDC3B RUN domain containing 3B
S100A9 S100 calcium binding protein A9
SAMD9 sterile alpha motif domain containing 9
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SERGEF secretion regulating guanine nucleotide exchange factor
SETD1A SET domain containing 1A
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMAD5 SMAD family member 5
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SMR3A submaxillary gland androgen regulated protein 3A
SPIN1 spindlin 1
SRD5A3 steroid 5 alpha-reductase 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TMEM242 transmembrane protein 242
TMEM38B transmembrane protein 38B
TMOD3 tropomodulin 3 (ubiquitous)
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TSGA10 testis specific, 10
UCN urocortin
VASH1 vasohibin 1
VASH2 vasohibin 2
ZBTB44 zinc finger and BTB domain containing 44
ZBTB6 zinc finger and BTB domain containing 6
ZNF141 zinc finger protein 141
ZNF34 zinc finger protein 34
ZNF37BP zinc finger protein 37B, pseudogene
ZNF423 zinc finger protein 423
ZNF506 zinc finger protein 506