| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the medrysone-4727 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ADAM12 | ADAM metallopeptidase domain 12 |
| ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif, 7 |
| ADORA1 | adenosine A1 receptor |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ARRB1 | arrestin, beta 1 |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CALML5 | calmodulin-like 5 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID |
| CARD10 | caspase recruitment domain family, member 10 |
| CCDC71 | coiled-coil domain containing 71 |
| CD209 | CD209 molecule |
| CD22 | CD22 molecule |
| CDC42 | cell division cycle 42 |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CLEC2B | C-type lectin domain family 2, member B |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
| COL1A1 | collagen, type I, alpha 1 |
| COMT | catechol-O-methyltransferase |
| CPNE7 | copine VII |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
| DFNA5 | deafness, autosomal dominant 5 |
| DGKA | diacylglycerol kinase, alpha 80kDa |
| DMRT1 | doublesex and mab-3 related transcription factor 1 |
| DUSP6 | dual specificity phosphatase 6 |
| EMID1 | EMI domain containing 1 |
| EMP1 | epithelial membrane protein 1 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 |
| EPHA5 | EPH receptor A5 |
| ESR1 | estrogen receptor 1 |
| ETV4 | ets variant 4 |
| FSCN1 | fascin actin-bundling protein 1 |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 |
| GPR85 | G protein-coupled receptor 85 |
| GRB10 | growth factor receptor-bound protein 10 |
| GRM7 | glutamate receptor, metabotropic 7 |
| GSK3A | glycogen synthase kinase 3 alpha |
| HDAC7 | histone deacetylase 7 |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| ITGB6 | integrin, beta 6 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KLF9 | Kruppel-like factor 9 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MAPT | microtubule-associated protein tau |
| MBD2 | methyl-CpG binding domain protein 2 |
| MINK1 | misshapen-like kinase 1 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MUC3A | mucin 3A, cell surface associated |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 |
| OPCML | opioid binding protein/cell adhesion molecule-like |
| PAX8 | paired box 8 |
| PCDH1 | protocadherin 1 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDE9A | phosphodiesterase 9A |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PSCA | prostate stem cell antigen |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 |
| PURA | purine-rich element binding protein A |
| PURG | purine-rich element binding protein G |
| PVRL1 | poliovirus receptor-related 1 (herpesvirus entry mediator C) |
| RBM19 | RNA binding motif protein 19 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RND1 | Rho family GTPase 1 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| SATB2 | SATB homeobox 2 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SERHL2 | serine hydrolase-like 2 |
| SLC18A3 | solute carrier family 18 (vesicular acetylcholine transporter), member 3 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SNED1 | sushi, nidogen and EGF-like domains 1 |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SYT12 | synaptotagmin XII |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TAT | tyrosine aminotransferase |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TFEB | transcription factor EB |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| VWA5A | von Willebrand factor A domain containing 5A |
| ZG16 | zymogen granule protein 16 |
| ZNF440 | zinc finger protein 440 |
| ZNF76 | zinc finger protein 76 |
| ZNF771 | zinc finger protein 771 |
| Symbol | Name |
|---|---|
| ADM | adrenomedullin |
| AFAP1 | actin filament associated protein 1 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CCDC121 | coiled-coil domain containing 121 |
| CCDC85C | coiled-coil domain containing 85C |
| CLSPN | claspin |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CSF1R | colony stimulating factor 1 receptor |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DMTN | dematin actin binding protein |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| EFNA3 | ephrin-A3 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| FILIP1L | filamin A interacting protein 1-like |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GLRA1 | glycine receptor, alpha 1 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GRAMD1C | GRAM domain containing 1C |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| HAMP | hepcidin antimicrobial peptide |
| HIRA | histone cell cycle regulator |
| HIST1H4D | histone cluster 1, H4d |
| HMOX1 | heme oxygenase 1 |
| HOXC10 | homeobox C10 |
| IFI6 | interferon, alpha-inducible protein 6 |
| KDM8 | lysine (K)-specific demethylase 8 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MITF | microphthalmia-associated transcription factor |
| MMP9 | matrix metallopeptidase 9 |
| MRPS18C | mitochondrial ribosomal protein S18C |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NKX3-2 | NK3 homeobox 2 |
| NPY1R | neuropeptide Y receptor Y1 |
| OLFML2A | olfactomedin-like 2A |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PCDHA5 | protocadherin alpha 5 |
| PCDHB13 | protocadherin beta 13 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PGR | progesterone receptor |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| POLM | polymerase (DNA directed), mu |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRF1 | perforin 1 (pore forming protein) |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| RAB3D | RAB3D, member RAS oncogene family |
| RFXAP | regulatory factor X-associated protein |
| RUNDC3B | RUN domain containing 3B |
| S100A9 | S100 calcium binding protein A9 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SETD1A | SET domain containing 1A |
| SLC16A7 | solute carrier family 16 (monocarboxylate transporter), member 7 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SMAD5 | SMAD family member 5 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SPIN1 | spindlin 1 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| THNSL2 | threonine synthase-like 2 (S. cerevisiae) |
| TMEM242 | transmembrane protein 242 |
| TMEM38B | transmembrane protein 38B |
| TMOD3 | tropomodulin 3 (ubiquitous) |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| TSGA10 | testis specific, 10 |
| UCN | urocortin |
| VASH1 | vasohibin 1 |
| VASH2 | vasohibin 2 |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF141 | zinc finger protein 141 |
| ZNF34 | zinc finger protein 34 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF423 | zinc finger protein 423 |
| ZNF506 | zinc finger protein 506 |