mefenamic acid-5534 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the mefenamic acid-5534 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
A4GALT alpha 1,4-galactosyltransferase
ACPP acid phosphatase, prostate
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
APCS amyloid P component, serum
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATG13 autophagy related 13
BTG2 BTG family, member 2
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CCL27 chemokine (C-C motif) ligand 27
CD3D CD3d molecule, delta (CD3-TCR complex)
CD70 CD70 molecule
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDHR2 cadherin-related family member 2
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHI3L2 chitinase 3-like 2
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CNTD2 cyclin N-terminal domain containing 2
COL13A1 collagen, type XIII, alpha 1
CUL3 cullin 3
DCN decorin
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
ELOVL2 ELOVL fatty acid elongase 2
EPHB2 EPH receptor B2
F13A1 coagulation factor XIII, A1 polypeptide
FABP3 fatty acid binding protein 3, muscle and heart
FHL1 four and a half LIM domains 1
FLOT1 flotillin 1
FZD10 frizzled class receptor 10
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GAB1 GRB2-associated binding protein 1
GAMT guanidinoacetate N-methyltransferase
GPER1 G protein-coupled estrogen receptor 1
GPR68 G protein-coupled receptor 68
HBS1L HBS1-like translational GTPase
HIST1H1E histone cluster 1, H1e
HNMT histamine N-methyltransferase
HOXA2 homeobox A2
ICOSLG inducible T-cell co-stimulator ligand
ID2B inhibitor of DNA binding 2B, dominant negative helix-loop-helix protein (pseudogene)
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
IL1RN interleukin 1 receptor antagonist
INPP5J inositol polyphosphate-5-phosphatase J
IPW imprinted in Prader-Willi syndrome (non-protein coding)
IRS2 insulin receptor substrate 2
ISG15 ISG15 ubiquitin-like modifier
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
LMO4 LIM domain only 4
MED15 mediator complex subunit 15
MED25 mediator complex subunit 25
MEGF6 multiple EGF-like-domains 6
NEURL1 neuralized E3 ubiquitin protein ligase 1
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NUP188 nucleoporin 188kDa
ONECUT1 one cut homeobox 1
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OSMR oncostatin M receptor
PCDHB3 protocadherin beta 3
PDC phosducin
PHC1 polyhomeotic homolog 1 (Drosophila)
PKNOX1 PBX/knotted 1 homeobox 1
PKNOX2 PBX/knotted 1 homeobox 2
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLXNC1 plexin C1
PNLIPRP2 pancreatic lipase-related protein 2
POU4F2 POU class 4 homeobox 2
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RPL3L ribosomal protein L3-like
RPL7 ribosomal protein L7
RRBP1 ribosome binding protein 1
SCN10A sodium channel, voltage gated, type X alpha subunit
SH3BP2 SH3-domain binding protein 2
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC12A8 solute carrier family 12, member 8
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STRN3 striatin, calmodulin binding protein 3
TAPBP TAP binding protein (tapasin)
TIMP3 TIMP metallopeptidase inhibitor 3
TMEM63A transmembrane protein 63A
TRIP11 thyroid hormone receptor interactor 11
TRO trophinin
TTLL5 tubulin tyrosine ligase-like family member 5
UNC93B1 unc-93 homolog B1 (C. elegans)
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
USP20 ubiquitin specific peptidase 20
VAC14 Vac14 homolog (S. cerevisiae)
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae)
WNT10B wingless-type MMTV integration site family, member 10B
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZNF747 zinc finger protein 747

decreased expression

Symbol Name
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AIDA axin interactor, dorsalization associated
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ATP13A2 ATPase type 13A2
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BAHD1 bromo adjacent homology domain containing 1
C11ORF30 chromosome 11 open reading frame 30
C1QTNF3 C1q and tumor necrosis factor related protein 3
CALCOCO1 calcium binding and coiled-coil domain 1
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDKN2AIP CDKN2A interacting protein
CDON cell adhesion associated, oncogene regulated
CES3 carboxylesterase 3
CFAP44 cilia and flagella associated protein 44
CIC capicua transcriptional repressor
CIR1 corepressor interacting with RBPJ, 1
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNR2 cannabinoid receptor 2 (macrophage)
CYB561D2 cytochrome b561 family, member D2
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
EFNA3 ephrin-A3
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
ERN2 endoplasmic reticulum to nucleus signaling 2
ETNK2 ethanolamine kinase 2
FAM120C family with sequence similarity 120C
FURIN furin (paired basic amino acid cleaving enzyme)
FXN frataxin
GSTCD glutathione S-transferase, C-terminal domain containing
HIST1H2AI histone cluster 1, H2ai
HOXC10 homeobox C10
HOXD11 homeobox D11
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
INTS9 integrator complex subunit 9
JUNB jun B proto-oncogene
KAT2A K(lysine) acetyltransferase 2A
LAX1 lymphocyte transmembrane adaptor 1
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC100272216 uncharacterized LOC100272216
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MAMLD1 mastermind-like domain containing 1
MYL5 myosin, light chain 5, regulatory
NARFL nuclear prelamin A recognition factor-like
NECAP2 NECAP endocytosis associated 2
NHEJ1 nonhomologous end-joining factor 1
NOL10 nucleolar protein 10
NOL6 nucleolar protein 6 (RNA-associated)
OGFRL1 opioid growth factor receptor-like 1
ORAI3 ORAI calcium release-activated calcium modulator 3
PCDHA9 protocadherin alpha 9
PDE8B phosphodiesterase 8B
PGPEP1 pyroglutamyl-peptidase I
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PRPH peripherin
PYCRL pyrroline-5-carboxylate reductase-like
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RIBC2 RIB43A domain with coiled-coils 2
RNF121 ring finger protein 121
RNF126P1 ring finger protein 126 pseudogene 1
RNF170 ring finger protein 170
RPL13P5 ribosomal protein L13 pseudogene 5
RUFY2 RUN and FYVE domain containing 2
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC35F5 solute carrier family 35, member F5
SLC41A3 solute carrier family 41, member 3
SLC44A1 solute carrier family 44 (choline transporter), member 1
SNORA21 small nucleolar RNA, H/ACA box 21
SSBP3 single stranded DNA binding protein 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TAGLN transgelin
TMEM242 transmembrane protein 242
TMEM62 transmembrane protein 62
TPRA1 transmembrane protein, adipocyte asscociated 1
TRAF2 TNF receptor-associated factor 2
TRAIP TRAF interacting protein
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TXLNA taxilin alpha
VGF VGF nerve growth factor inducible
WDR19 WD repeat domain 19
XAB2 XPA binding protein 2
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF16 zinc finger protein 16
ZNF219 zinc finger protein 219
ZNF250 zinc finger protein 250
ZNF254 zinc finger protein 254
ZNF365 zinc finger protein 365
ZNF571 zinc finger protein 571
ZNF668 zinc finger protein 668