mefexamide-1438 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the mefexamide-1438 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AGRP agouti related neuropeptide
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
AKTIP AKT interacting protein
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATG12 autophagy related 12
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
BTN2A1 butyrophilin, subfamily 2, member A1
CCDC64 coiled-coil domain containing 64
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLCN5 chloride channel, voltage-sensitive 5
CTNND1 catenin (cadherin-associated protein), delta 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DAGLA diacylglycerol lipase, alpha
ELMO2 engulfment and cell motility 2
FAM64A family with sequence similarity 64, member A
FBXO31 F-box protein 31
FEM1B fem-1 homolog b (C. elegans)
FKBP1A FK506 binding protein 1A, 12kDa
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GAA glucosidase, alpha; acid
GAS8 growth arrest-specific 8
GATA3 GATA binding protein 3
GCAT glycine C-acetyltransferase
GEMIN4 gem (nuclear organelle) associated protein 4
GHRHR growth hormone releasing hormone receptor
GIMAP5 GTPase, IMAP family member 5
GK glycerol kinase
GLI3 GLI family zinc finger 3
GON4L gon-4-like (C. elegans)
GPR20 G protein-coupled receptor 20
HP1BP3 heterochromatin protein 1, binding protein 3
IDO1 indoleamine 2,3-dioxygenase 1
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IL18RAP interleukin 18 receptor accessory protein
INTS7 integrator complex subunit 7
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KDM2A lysine (K)-specific demethylase 2A
KLF6 Kruppel-like factor 6
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LMAN1 lectin, mannose-binding, 1
LRRN2 leucine rich repeat neuronal 2
MAGED2 melanoma antigen family D2
MED18 mediator complex subunit 18
MED20 mediator complex subunit 20
MINK1 misshapen-like kinase 1
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MT3 metallothionein 3
MTMR3 myotubularin related protein 3
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NACA nascent polypeptide-associated complex alpha subunit
NAT6 N-acetyltransferase 6 (GCN5-related)
NDRG2 NDRG family member 2
NELL2 NEL-like 2 (chicken)
NENF neudesin neurotrophic factor
NF1 neurofibromin 1
NOP16 NOP16 nucleolar protein
OR10J1 olfactory receptor, family 10, subfamily J, member 1
OR2S2 olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene)
OSBPL3 oxysterol binding protein-like 3
PADI1 peptidyl arginine deiminase, type I
PADI4 peptidyl arginine deiminase, type IV
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PEX14 peroxisomal biogenesis factor 14
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PREP prolyl endopeptidase
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RREB1 ras responsive element binding protein 1
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMYD5 SMYD family member 5
SPATA20 spermatogenesis associated 20
SPN sialophorin
SPPL2B signal peptide peptidase like 2B
SRF serum response factor (c-fos serum response element-binding transcription factor)
STAC SH3 and cysteine rich domain
TBL1X transducin (beta)-like 1X-linked
TCF3 transcription factor 3
TK2 thymidine kinase 2, mitochondrial
TMEM194A transmembrane protein 194A
TNS1 tensin 1
TOP3A topoisomerase (DNA) III alpha
TRMT61A tRNA methyltransferase 61A
TUBB3 tubulin, beta 3 class III
VIPR2 vasoactive intestinal peptide receptor 2
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZNF222 zinc finger protein 222
ZNF248 zinc finger protein 248
ZNF280D zinc finger protein 280D
ZNF614 zinc finger protein 614

decreased expression

Symbol Name
AACS acetoacetyl-CoA synthetase
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ACSL4 acyl-CoA synthetase long-chain family member 4
AHR aryl hydrocarbon receptor
APOD apolipoprotein D
AZI2 5-azacytidine induced 2
BBC3 BCL2 binding component 3
C11ORF68 chromosome 11 open reading frame 68
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
CD302 CD302 molecule
CFAP74 cilia and flagella associated protein 74
CIC capicua transcriptional repressor
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CRY1 cryptochrome circadian clock 1
CRYBG3 beta-gamma crystallin domain containing 3
CTRL chymotrypsin-like
CTSK cathepsin K
DAZAP1 DAZ associated protein 1
DCLRE1B DNA cross-link repair 1B
DENND4A DENN/MADD domain containing 4A
DMXL1 Dmx-like 1
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DTWD1 DTW domain containing 1
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
EBNA1BP2 EBNA1 binding protein 2
EFCAB2 EF-hand calcium binding domain 2
ELP5 elongator acetyltransferase complex subunit 5
EVL Enah/Vasp-like
FADS2 fatty acid desaturase 2
FBXO5 F-box protein 5
GALR3 galanin receptor 3
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GJD2 gap junction protein, delta 2, 36kDa
GRM4 glutamate receptor, metabotropic 4
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
IFT57 intraflagellar transport 57
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KCNK5 potassium channel, two pore domain subfamily K, member 5
KCTD3 potassium channel tetramerization domain containing 3
KIF3B kinesin family member 3B
KIFC1 kinesin family member C1
LMBR1L limb development membrane protein 1-like
LOC642236 FSHD region gene 1 pseudogene
LSP1 lymphocyte-specific protein 1
MAP1S microtubule-associated protein 1S
MED15 mediator complex subunit 15
MED9 mediator complex subunit 9
METRN meteorin, glial cell differentiation regulator
MFSD11 major facilitator superfamily domain containing 11
MICA MHC class I polypeptide-related sequence A
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NAT9 N-acetyltransferase 9 (GCN5-related, putative)
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa
PIBF1 progesterone immunomodulatory binding factor 1
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
POLI polymerase (DNA directed) iota
POTEKP POTE ankyrin domain family, member K, pseudogene
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RECQL4 RecQ protein-like 4
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RPL26 ribosomal protein L26
RPS14P3 ribosomal protein S14 pseudogene 3
RPS4Y1 ribosomal protein S4, Y-linked 1
SCML2 sex comb on midleg-like 2 (Drosophila)
SKI SKI proto-oncogene
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12)
SPX spexin hormone
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TMEM177 transmembrane protein 177
TMEM242 transmembrane protein 242
TNRC6B trinucleotide repeat containing 6B
TOM1L1 target of myb1 (chicken)-like 1
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAPPC12 trafficking protein particle complex 12
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TTF2 transcription termination factor, RNA polymerase II
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBQLN4 ubiquilin 4
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
YEATS4 YEATS domain containing 4
ZBED1 zinc finger, BED-type containing 1
ZCCHC10 zinc finger, CCHC domain containing 10
ZEB2 zinc finger E-box binding homeobox 2
ZNF140 zinc finger protein 140
ZNF175 zinc finger protein 175
ZNF23 zinc finger protein 23
ZNF250 zinc finger protein 250
ZNF264 zinc finger protein 264
ZNHIT2 zinc finger, HIT-type containing 2