| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the mefexamide-2121 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAN | aggrecan |
| ACOX3 | acyl-CoA oxidase 3, pristanoyl |
| AHI1 | Abelson helper integration site 1 |
| AK1 | adenylate kinase 1 |
| ANKRD12 | ankyrin repeat domain 12 |
| APP | amyloid beta (A4) precursor protein |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| ASMTL | acetylserotonin O-methyltransferase-like |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BCHE | butyrylcholinesterase |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C1ORF21 | chromosome 1 open reading frame 21 |
| CEP164 | centrosomal protein 164kDa |
| CSF1R | colony stimulating factor 1 receptor |
| CYLC1 | cylicin, basic protein of sperm head cytoskeleton 1 |
| DCTN1 | dynactin 1 |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DLG3 | discs, large homolog 3 (Drosophila) |
| DTX3 | deltex 3, E3 ubiquitin ligase |
| EPHA4 | EPH receptor A4 |
| ETV5 | ets variant 5 |
| FGF5 | fibroblast growth factor 5 |
| FGFR4 | fibroblast growth factor receptor 4 |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GOLGA2 | golgin A2 |
| HNMT | histamine N-methyltransferase |
| HOOK1 | hook microtubule-tethering protein 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| INSIG1 | insulin induced gene 1 |
| JUND | jun D proto-oncogene |
| KIAA0754 | KIAA0754 |
| KIRREL | kin of IRRE like (Drosophila) |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LDB1 | LIM domain binding 1 |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LRP6 | low density lipoprotein receptor-related protein 6 |
| MANBA | mannosidase, beta A, lysosomal |
| MAP3K12 | mitogen-activated protein kinase kinase kinase 12 |
| MDFI | MyoD family inhibitor |
| MDFIC | MyoD family inhibitor domain containing |
| MMP9 | matrix metallopeptidase 9 |
| MTUS1 | microtubule associated tumor suppressor 1 |
| MUC3A | mucin 3A, cell surface associated |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) |
| NOL12 | nucleolar protein 12 |
| NOP14-AS1 | NOP14 antisense RNA 1 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCBP2 | poly(rC) binding protein 2 |
| PCDH11Y | protocadherin 11 Y-linked |
| PCIF1 | PDX1 C-terminal inhibiting factor 1 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PIGC | phosphatidylinositol glycan anchor biosynthesis, class C |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
| PRPF18 | pre-mRNA processing factor 18 |
| PTGDR2 | prostaglandin D2 receptor 2 |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| RAB27B | RAB27B, member RAS oncogene family |
| RBM19 | RNA binding motif protein 19 |
| REST | RE1-silencing transcription factor |
| RGS10 | regulator of G-protein signaling 10 |
| RGS14 | regulator of G-protein signaling 14 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| S100A11 | S100 calcium binding protein A11 |
| S100A3 | S100 calcium binding protein A3 |
| SIRT5 | sirtuin 5 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| STAG3 | stromal antigen 3 |
| STK4 | serine/threonine kinase 4 |
| STS | steroid sulfatase (microsomal), isozyme S |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TAF5L | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TAGLN3 | transgelin 3 |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TLE3 | transducin-like enhancer of split 3 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 |
| TMEM180 | transmembrane protein 180 |
| TMEM63A | transmembrane protein 63A |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| TRAPPC10 | trafficking protein particle complex 10 |
| TRIM14 | tripartite motif containing 14 |
| TSPAN1 | tetraspanin 1 |
| VEGFB | vascular endothelial growth factor B |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZBTB43 | zinc finger and BTB domain containing 43 |
| ZNF444 | zinc finger protein 444 |
| ZNF747 | zinc finger protein 747 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ABCA11P | ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene |
| ABHD4 | abhydrolase domain containing 4 |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BCL2L2 | BCL2-like 2 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| BLMH | bleomycin hydrolase |
| BNC1 | basonuclin 1 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CCNJL | cyclin J-like |
| CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase |
| CEP97 | centrosomal protein 97kDa |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLSPN | claspin |
| CORO2A | coronin, actin binding protein, 2A |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CPVL | carboxypeptidase, vitellogenic-like |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| EDC4 | enhancer of mRNA decapping 4 |
| EDN1 | endothelin 1 |
| ERCC5 | excision repair cross-complementation group 5 |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FBXO2 | F-box protein 2 |
| FMO4 | flavin containing monooxygenase 4 |
| GLDC | glycine dehydrogenase (decarboxylating) |
| HINFP | histone H4 transcription factor |
| HIRA | histone cell cycle regulator |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| HOXB9 | homeobox B9 |
| HSPA1L | heat shock 70kDa protein 1-like |
| HYI | hydroxypyruvate isomerase (putative) |
| IL4R | interleukin 4 receptor |
| INPPL1 | inositol polyphosphate phosphatase-like 1 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KLF3 | Kruppel-like factor 3 (basic) |
| KRT8P12 | keratin 8 pseudogene 12 |
| LAMC3 | laminin, gamma 3 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LRRC61 | leucine rich repeat containing 61 |
| MAGEH1 | melanoma antigen family H1 |
| MOSPD3 | motile sperm domain containing 3 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NCS1 | neuronal calcium sensor 1 |
| NDRG4 | NDRG family member 4 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 |
| OLFML2A | olfactomedin-like 2A |
| PHACTR4 | phosphatase and actin regulator 4 |
| PLAC8 | placenta-specific 8 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| PMCH | pro-melanin-concentrating hormone |
| POM121 | POM121 transmembrane nucleoporin |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| PSKH1 | protein serine kinase H1 |
| QSER1 | glutamine and serine rich 1 |
| RAB4B | RAB4B, member RAS oncogene family |
| RANBP17 | RAN binding protein 17 |
| RNF2 | ring finger protein 2 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SECTM1 | secreted and transmembrane 1 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SHPK | sedoheptulokinase |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SYT17 | synaptotagmin XVII |
| THBS3 | thrombospondin 3 |
| TIPRL | TOR signaling pathway regulator |
| TMEM121 | transmembrane protein 121 |
| TMEM159 | transmembrane protein 159 |
| TMEM183A | transmembrane protein 183A |
| TMEM8B | transmembrane protein 8B |
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TRIM66 | tripartite motif containing 66 |
| TSPAN8 | tetraspanin 8 |
| TUBA3D | tubulin, alpha 3d |
| TUBB2B | tubulin, beta 2B class IIb |
| TXLNG | taxilin gamma |
| WDR43 | WD repeat domain 43 |
| WNT5B | wingless-type MMTV integration site family, member 5B |
| ZNF141 | zinc finger protein 141 |
| ZNF180 | zinc finger protein 180 |
| ZNF8 | zinc finger protein 8 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |