| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the mefloquine-1364 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ANKRD12 | ankyrin repeat domain 12 |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 |
| ARMCX3 | armadillo repeat containing, X-linked 3 |
| ASAH1 | N-acylsphingosine amidohydrolase (acid ceramidase) 1 |
| ASMTL | acetylserotonin O-methyltransferase-like |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 |
| BCL7C | B-cell CLL/lymphoma 7C |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| BMI1 | BMI1 proto-oncogene, polycomb ring finger |
| C19ORF66 | chromosome 19 open reading frame 66 |
| C5ORF28 | chromosome 5 open reading frame 28 |
| CCDC53 | coiled-coil domain containing 53 |
| CCL4 | chemokine (C-C motif) ligand 4 |
| CCNA1 | cyclin A1 |
| CD83 | CD83 molecule |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CLIP1 | CAP-GLY domain containing linker protein 1 |
| COL4A3BP | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein |
| CXCL10 | chemokine (C-X-C motif) ligand 10 |
| DENND2D | DENN/MADD domain containing 2D |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| EPOR | erythropoietin receptor |
| FAF2 | Fas associated factor family member 2 |
| FAM105A | family with sequence similarity 105, member A |
| FTH1 | ferritin, heavy polypeptide 1 |
| FTH1P5 | ferritin, heavy polypeptide 1 pseudogene 5 |
| GCLM | glutamate-cysteine ligase, modifier subunit |
| GPNMB | glycoprotein (transmembrane) nmb |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa |
| IFI16 | interferon, gamma-inducible protein 16 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IGKC | immunoglobulin kappa constant |
| IL1RAP | interleukin 1 receptor accessory protein |
| IRF9 | interferon regulatory factor 9 |
| ISG15 | ISG15 ubiquitin-like modifier |
| KLF2 | Kruppel-like factor 2 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| KTN1 | kinectin 1 (kinesin receptor) |
| LGALS3 | lectin, galactoside-binding, soluble, 3 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MAST2 | microtubule associated serine/threonine kinase 2 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MED13L | mediator complex subunit 13-like |
| METTL5 | methyltransferase like 5 |
| METTL7A | methyltransferase like 7A |
| MPP6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1G | metallothionein 1G |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1X | metallothionein 1X |
| MT2A | metallothionein 2A |
| MX1 | MX dynamin-like GTPase 1 |
| NDE1 | nudE neurodevelopment protein 1 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive |
| NUP160 | nucleoporin 160kDa |
| PIDD1 | p53-induced death domain protein 1 |
| PLCD1 | phospholipase C, delta 1 |
| POR | P450 (cytochrome) oxidoreductase |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
| RAB4B | RAB4B, member RAS oncogene family |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit |
| RECQL4 | RecQ protein-like 4 |
| RET | ret proto-oncogene |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| RPS14P3 | ribosomal protein S14 pseudogene 3 |
| RPS2 | ribosomal protein S2 |
| SEC24D | SEC24 family member D |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC25A44 | solute carrier family 25, member 44 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 |
| SMG5 | SMG5 nonsense mediated mRNA decay factor |
| SPP1 | secreted phosphoprotein 1 |
| SQSTM1 | sequestosome 1 |
| SRI | sorcin |
| STAT1 | signal transducer and activator of transcription 1, 91kDa |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMEM127 | transmembrane protein 127 |
| TMEM251 | transmembrane protein 251 |
| TPT1 | tumor protein, translationally-controlled 1 |
| TSC22D2 | TSC22 domain family, member 2 |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| XYLT1 | xylosyltransferase I |
| ZEB2 | zinc finger E-box binding homeobox 2 |
| ZKSCAN4 | zinc finger with KRAB and SCAN domains 4 |
| ZNF79 | zinc finger protein 79 |
| ZSWIM8 | zinc finger, SWIM-type containing 8 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ACIN1 | apoptotic chromatin condensation inducer 1 |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADM | adrenomedullin |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| ASCC1 | activating signal cointegrator 1 complex subunit 1 |
| ATG9A | autophagy related 9A |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| BTNL3 | butyrophilin-like 3 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CD38 | CD38 molecule |
| CLTCL1 | clathrin, heavy chain-like 1 |
| COMMD10 | COMM domain containing 10 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CPA2 | carboxypeptidase A2 (pancreatic) |
| CTDNEP1 | CTD nuclear envelope phosphatase 1 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| DFFA | DNA fragmentation factor, 45kDa, alpha polypeptide |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 |
| DOK2 | docking protein 2, 56kDa |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| ERCC3 | excision repair cross-complementation group 3 |
| GAA | glucosidase, alpha; acid |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 |
| GDF9 | growth differentiation factor 9 |
| GLB1L2 | galactosidase, beta 1-like 2 |
| GRM6 | glutamate receptor, metabotropic 6 |
| GTF2E1 | general transcription factor IIE, polypeptide 1, alpha 56kDa |
| IL1B | interleukin 1, beta |
| IL2RB | interleukin 2 receptor, beta |
| IL4R | interleukin 4 receptor |
| ILK | integrin-linked kinase |
| INTS9 | integrator complex subunit 9 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIF3B | kinesin family member 3B |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LSP1 | lymphocyte-specific protein 1 |
| MAGEF1 | melanoma antigen family F1 |
| MCM10 | minichromosome maintenance complex component 10 |
| MCTP1 | multiple C2 domains, transmembrane 1 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MMP9 | matrix metallopeptidase 9 |
| MON1B | MON1 secretory trafficking family member B |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| MTMR11 | myotubularin related protein 11 |
| NDRG1 | N-myc downstream regulated 1 |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NFE2 | nuclear factor, erythroid 2 |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| NUBP2 | nucleotide binding protein 2 |
| NXPH3 | neurexophilin 3 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PADI1 | peptidyl arginine deiminase, type I |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 |
| PES1 | pescadillo ribosomal biogenesis factor 1 |
| PLAC8 | placenta-specific 8 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PPM1G | protein phosphatase, Mg2+/Mn2+ dependent, 1G |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) |
| PSTPIP1 | proline-serine-threonine phosphatase interacting protein 1 |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| S100A9 | S100 calcium binding protein A9 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SIRT6 | sirtuin 6 |
| SKIV2L2 | superkiller viralicidic activity 2-like 2 (S. cerevisiae) |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SNTA1 | syntrophin, alpha 1 |
| STAC | SH3 and cysteine rich domain |
| STARD8 | StAR-related lipid transfer (START) domain containing 8 |
| STEAP3 | STEAP family member 3, metalloreductase |
| STRA13 | stimulated by retinoic acid 13 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| TBL3 | transducin (beta)-like 3 |
| TERT | telomerase reverse transcriptase |
| TESC | tescalcin |
| TEX40 | testis expressed 40 |
| THBS4 | thrombospondin 4 |
| TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| TSPAN32 | tetraspanin 32 |
| TXLNA | taxilin alpha |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| WDR19 | WD repeat domain 19 |
| WT1-AS | WT1 antisense RNA |
| XKR8 | XK, Kell blood group complex subunit-related family, member 8 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |
| ZSCAN9 | zinc finger and SCAN domain containing 9 |
