| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
199 genes differentially expressed following the mefloquine-2048 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ARL2BP | ADP-ribosylation factor-like 2 binding protein |
| ARSD | arylsulfatase D |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BCL2 | B-cell CLL/lymphoma 2 |
| BCL6 | B-cell CLL/lymphoma 6 |
| CBLB | Cbl proto-oncogene B, E3 ubiquitin protein ligase |
| CCNG2 | cyclin G2 |
| CCNJ | cyclin J |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CEP68 | centrosomal protein 68kDa |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CPZ | carboxypeptidase Z |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CTNS | cystinosin, lysosomal cystine transporter |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DSC2 | desmocollin 2 |
| DUSP10 | dual specificity phosphatase 10 |
| DVL2 | dishevelled segment polarity protein 2 |
| FCMR | Fc fragment of IgM receptor |
| FLJ22184 | |
| FTH1 | ferritin, heavy polypeptide 1 |
| GK | glycerol kinase |
| GPATCH3 | G patch domain containing 3 |
| GRB10 | growth factor receptor-bound protein 10 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
| HDAC9 | histone deacetylase 9 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HHAT | hedgehog acyltransferase |
| HMOX1 | heme oxygenase 1 |
| IDS | iduronate 2-sulfatase |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| INSIG1 | insulin induced gene 1 |
| IRS2 | insulin receptor substrate 2 |
| KLF3 | Kruppel-like factor 3 (basic) |
| KLHL24 | kelch-like family member 24 |
| LDLR | low density lipoprotein receptor |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LMOD1 | leiomodin 1 (smooth muscle) |
| MMP1 | matrix metallopeptidase 1 |
| MMP10 | matrix metallopeptidase 10 |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1M | metallothionein 1M |
| MT1X | metallothionein 1X |
| MT2A | metallothionein 2A |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| N4BP1 | NEDD4 binding protein 1 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NEK3 | NIMA-related kinase 3 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| QSER1 | glutamine and serine rich 1 |
| RGS4 | regulator of G-protein signaling 4 |
| RND3 | Rho family GTPase 3 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RRAGC | Ras-related GTP binding C |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
| SQSTM1 | sequestosome 1 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| STX3 | syntaxin 3 |
| SUGP1 | SURP and G patch domain containing 1 |
| SYT1 | synaptotagmin I |
| TMEM135 | transmembrane protein 135 |
| TPP1 | tripeptidyl peptidase I |
| TRIB3 | tribbles pseudokinase 3 |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| ZFHX2 | zinc finger homeobox 2 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZMYM5 | zinc finger, MYM-type 5 |
| ZNF165 | zinc finger protein 165 |
| ZNF358 | zinc finger protein 358 |
| Symbol | Name |
|---|---|
| ADAT1 | adenosine deaminase, tRNA-specific 1 |
| ALAS1 | 5'-aminolevulinate synthase 1 |
| ANAPC2 | anaphase promoting complex subunit 2 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BCL2A1 | BCL2-related protein A1 |
| BDNF | brain-derived neurotrophic factor |
| C1GALT1C1 | C1GALT1-specific chaperone 1 |
| C4ORF19 | chromosome 4 open reading frame 19 |
| CCS | copper chaperone for superoxide dismutase |
| CDKN2AIP | CDKN2A interacting protein |
| CHMP1A | charged multivesicular body protein 1A |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| COA4 | cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain |
| CTNNBL1 | catenin, beta like 1 |
| DCLRE1A | DNA cross-link repair 1A |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DMBT1 | deleted in malignant brain tumors 1 |
| E2F8 | E2F transcription factor 8 |
| EDC4 | enhancer of mRNA decapping 4 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| ERCC5 | excision repair cross-complementation group 5 |
| EVL | Enah/Vasp-like |
| FAM127B | family with sequence similarity 127, member B |
| GBX2 | gastrulation brain homeobox 2 |
| GEMIN4 | gem (nuclear organelle) associated protein 4 |
| GID4 | GID complex subunit 4 |
| GLT8D2 | glycosyltransferase 8 domain containing 2 |
| GPR176 | G protein-coupled receptor 176 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| HAS2 | hyaluronan synthase 2 |
| HOXB13 | homeobox B13 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 |
| IRS1 | insulin receptor substrate 1 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| JMJD4 | jumonji domain containing 4 |
| JUNB | jun B proto-oncogene |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0020 | KIAA0020 |
| KIAA0556 | KIAA0556 |
| KIAA1549L | KIAA1549-like |
| LRRC20 | leucine rich repeat containing 20 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MALL | mal, T-cell differentiation protein-like |
| MCM10 | minichromosome maintenance complex component 10 |
| MITF | microphthalmia-associated transcription factor |
| MOB3B | MOB kinase activator 3B |
| MPC1 | mitochondrial pyruvate carrier 1 |
| MTERF1 | mitochondrial transcription termination factor 1 |
| MYBBP1A | MYB binding protein (P160) 1a |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit |
| NAGPA | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase |
| NBEAL2 | neurobeachin-like 2 |
| NFS1 | NFS1 cysteine desulfurase |
| NOP2 | NOP2 nucleolar protein |
| NPDC1 | neural proliferation, differentiation and control, 1 |
| NUBP2 | nucleotide binding protein 2 |
| OXTR | oxytocin receptor |
| PARD6A | par-6 family cell polarity regulator alpha |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PHF10 | PHD finger protein 10 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 |
| POLA2 | polymerase (DNA directed), alpha 2, accessory subunit |
| PPAT | phosphoribosyl pyrophosphate amidotransferase |
| PPFIA3 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
| PRAME | preferentially expressed antigen in melanoma |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| PRSS8 | protease, serine, 8 |
| PTK7 | protein tyrosine kinase 7 (inactive) |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) |
| PYCARD | PYD and CARD domain containing |
| RUSC2 | RUN and SH3 domain containing 2 |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SYNPO | synaptopodin |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TFRC | transferrin receptor |
| THAP7 | THAP domain containing 7 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) |
| TMEM2 | transmembrane protein 2 |
| TMOD3 | tropomodulin 3 (ubiquitous) |
| UCK2 | uridine-cytidine kinase 2 |
| USP18 | ubiquitin specific peptidase 18 |
| UTP20 | UTP20, small subunit (SSU) processome component, homolog (yeast) |
| WDR5B | WD repeat domain 5B |
| WNT7A | wingless-type MMTV integration site family, member 7A |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZC4H2 | zinc finger, C4H2 domain containing |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZNF177 | zinc finger protein 177 |
