| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the mefloquine-2210 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ATF3 | activating transcription factor 3 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DLX2 | distal-less homeobox 2 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP10 | dual specificity phosphatase 10 |
| EFNA1 | ephrin-A1 |
| EGR1 | early growth response 1 |
| ELL2 | elongation factor, RNA polymerase II, 2 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| FAM46C | family with sequence similarity 46, member C |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| HBEGF | heparin-binding EGF-like growth factor |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HES1 | hes family bHLH transcription factor 1 |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H2AE | histone cluster 1, H2ae |
| HIST1H2AG | histone cluster 1, H2ag |
| HIST1H2BC | histone cluster 1, H2bc |
| HIST1H2BF | histone cluster 1, H2bf |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST1H2BH | histone cluster 1, H2bh |
| HIST1H2BI | histone cluster 1, H2bi |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H2BO | histone cluster 1, H2bo |
| HIST1H3B | histone cluster 1, H3b |
| HIST1H4E | histone cluster 1, H4e |
| HIST1H4H | histone cluster 1, H4h |
| HIST2H2BE | histone cluster 2, H2be |
| HMOX1 | heme oxygenase 1 |
| HOXB2 | homeobox B2 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| ICAM1 | intercellular adhesion molecule 1 |
| IER2 | immediate early response 2 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFNB1 | interferon, beta 1, fibroblast |
| IL32 | interleukin 32 |
| INHBE | inhibin, beta E |
| IRF1 | interferon regulatory factor 1 |
| IRS2 | insulin receptor substrate 2 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) |
| JUN | jun proto-oncogene |
| JUNB | jun B proto-oncogene |
| KLF10 | Kruppel-like factor 10 |
| KLF2 | Kruppel-like factor 2 |
| KLF6 | Kruppel-like factor 6 |
| KLHL24 | kelch-like family member 24 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1G | metallothionein 1G |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1X | metallothionein 1X |
| MT2A | metallothionein 2A |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| RCAN1 | regulator of calcineurin 1 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RGS2 | regulator of G-protein signaling 2 |
| RHOB | ras homolog family member B |
| RND1 | Rho family GTPase 1 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SMEK1 | SMEK homolog 1, suppressor of mek1 (Dictyostelium) |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPRY4 | sprouty homolog 4 (Drosophila) |
| SQSTM1 | sequestosome 1 |
| TEX14 | testis expressed 14 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TRIB3 | tribbles pseudokinase 3 |
| TSC22D3 | TSC22 domain family, member 3 |
| TXNIP | thioredoxin interacting protein |
| VEGFA | vascular endothelial growth factor A |
| ZFP36 | ZFP36 ring finger protein |
| ZNF10 | zinc finger protein 10 |
| ZNF165 | zinc finger protein 165 |
| Symbol | Name |
|---|---|
| AHNAK2 | AHNAK nucleoprotein 2 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| BATF | basic leucine zipper transcription factor, ATF-like |
| BCL9 | B-cell CLL/lymphoma 9 |
| BMP4 | bone morphogenetic protein 4 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| CD34 | CD34 molecule |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHMP6 | charged multivesicular body protein 6 |
| CORO7 | coronin 7 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
| DIXDC1 | DIX domain containing 1 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FBXO22 | F-box protein 22 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GAMT | guanidinoacetate N-methyltransferase |
| GID4 | GID complex subunit 4 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GRPR | gastrin-releasing peptide receptor |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GSTM5 | glutathione S-transferase mu 5 |
| HIRA | histone cell cycle regulator |
| IFT140 | intraflagellar transport 140 |
| IFT54 | intraflagellar transport 54 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KIAA0894 | KIAA0894 protein |
| KIF13A | kinesin family member 13A |
| KRT15 | keratin 15, type I |
| LOC730101 | uncharacterized LOC730101 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LRRC20 | leucine rich repeat containing 20 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MAP6D1 | MAP6 domain containing 1 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 |
| MCC | mutated in colorectal cancers |
| MGC12488 | |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MYOZ1 | myozenin 1 |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NLRX1 | NLR family member X1 |
| NOL10 | nucleolar protein 10 |
| NOL12 | nucleolar protein 12 |
| NPFFR1 | neuropeptide FF receptor 1 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PCDHB8 | protocadherin beta 8 |
| PICK1 | protein interacting with PRKCA 1 |
| PLA2G10 | phospholipase A2, group X |
| PLD2 | phospholipase D2 |
| PLD3 | phospholipase D family, member 3 |
| PODXL2 | podocalyxin-like 2 |
| POLH | polymerase (DNA directed), eta |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| PPAN | peter pan homolog (Drosophila) |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNF121 | ring finger protein 121 |
| RNF208 | ring finger protein 208 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| ROM1 | retinal outer segment membrane protein 1 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SCAI | suppressor of cancer cell invasion |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SKI | SKI proto-oncogene |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SP1 | Sp1 transcription factor |
| STAB2 | stabilin 2 |
| STMN3 | stathmin-like 3 |
| SYNC | syncoilin, intermediate filament protein |
| TESC | tescalcin |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| THEM6 | thioesterase superfamily member 6 |
| TLN1 | talin 1 |
| TRIM21 | tripartite motif containing 21 |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| UBTD1 | ubiquitin domain containing 1 |
| UPK3B | uroplakin 3B |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| XYLT2 | xylosyltransferase II |
