| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the mefloquine-5724 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AMACR | alpha-methylacyl-CoA racemase |
| AMH | anti-Mullerian hormone |
| ARC | activity-regulated cytoskeleton-associated protein |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATF3 | activating transcription factor 3 |
| BMP1 | bone morphogenetic protein 1 |
| BMP2 | bone morphogenetic protein 2 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDC25C | cell division cycle 25C |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| COPE | coatomer protein complex, subunit epsilon |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| DGKQ | diacylglycerol kinase, theta 110kDa |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP10 | dual specificity phosphatase 10 |
| EGR1 | early growth response 1 |
| FAM110B | family with sequence similarity 110, member B |
| FGF2 | fibroblast growth factor 2 (basic) |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GK | glycerol kinase |
| GPC3 | glypican 3 |
| HDAC9 | histone deacetylase 9 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HIST1H2BJ | histone cluster 1, H2bj |
| HMOX1 | heme oxygenase 1 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| IFIH1 | interferon induced with helicase C domain 1 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IL24 | interleukin 24 |
| IL6 | interleukin 6 |
| INHBA | inhibin, beta A |
| INSIG1 | insulin induced gene 1 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| JUN | jun proto-oncogene |
| JUND | jun D proto-oncogene |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KLF4 | Kruppel-like factor 4 (gut) |
| KLF6 | Kruppel-like factor 6 |
| KLHL24 | kelch-like family member 24 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| KRT16 | keratin 16, type I |
| KRT17 | keratin 17, type I |
| KRT34 | keratin 34, type I |
| KYNU | kynureninase |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 |
| MEGF6 | multiple EGF-like-domains 6 |
| MMP13 | matrix metallopeptidase 13 |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1G | metallothionein 1G |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1M | metallothionein 1M |
| MT1X | metallothionein 1X |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NR1H4 | nuclear receptor subfamily 1, group H, member 4 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PDLIM5 | PDZ and LIM domain 5 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTPRR | protein tyrosine phosphatase, receptor type, R |
| RND1 | Rho family GTPase 1 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SQSTM1 | sequestosome 1 |
| STC2 | stanniocalcin 2 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TRANK1 | tetratricopeptide repeat and ankyrin repeat containing 1 |
| TRIB3 | tribbles pseudokinase 3 |
| TTC39A | tetratricopeptide repeat domain 39A |
| YIPF2 | Yip1 domain family, member 2 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZFP36 | ZFP36 ring finger protein |
| ZNF165 | zinc finger protein 165 |
| Symbol | Name |
|---|---|
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 |
| ADCY6 | adenylate cyclase 6 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AEN | apoptosis enhancing nuclease |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ANOS1 | anosmin 1 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ARRB2 | arrestin, beta 2 |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| C5 | complement component 5 |
| CAPN15 | calpain 15 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCDC25 | coiled-coil domain containing 25 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CISH | cytokine inducible SH2-containing protein |
| COBL | cordon-bleu WH2 repeat protein |
| CPA4 | carboxypeptidase A4 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DBF4B | DBF4 zinc finger B |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| E2F8 | E2F transcription factor 8 |
| EN1 | engrailed homeobox 1 |
| EPN3 | epsin 3 |
| FAM184A | family with sequence similarity 184, member A |
| FGL1 | fibrinogen-like 1 |
| GALK1 | galactokinase 1 |
| GALT | galactose-1-phosphate uridylyltransferase |
| GJC1 | gap junction protein, gamma 1, 45kDa |
| GRPR | gastrin-releasing peptide receptor |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HELLS | helicase, lymphoid-specific |
| HIST1H3G | histone cluster 1, H3g |
| HOOK1 | hook microtubule-tethering protein 1 |
| HOXA4 | homeobox A4 |
| HOXB13 | homeobox B13 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KIAA0754 | KIAA0754 |
| KIAA1462 | KIAA1462 |
| KIF20A | kinesin family member 20A |
| LMNB1 | lamin B1 |
| LPAR3 | lysophosphatidic acid receptor 3 |
| MED24 | mediator complex subunit 24 |
| MOSPD3 | motile sperm domain containing 3 |
| MOXD1 | monooxygenase, DBH-like 1 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MX1 | MX dynamin-like GTPase 1 |
| NCAPH | non-SMC condensin I complex, subunit H |
| NDP | Norrie disease (pseudoglioma) |
| NINJ1 | ninjurin 1 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NOL12 | nucleolar protein 12 |
| NOTCH1 | notch 1 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| OSMR | oncostatin M receptor |
| P3H2 | prolyl 3-hydroxylase 2 |
| P3H4 | prolyl 3-hydroxylase family member 4 (non-enzymatic) |
| PADI1 | peptidyl arginine deiminase, type I |
| PALMD | palmdelphin |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| PRR14L | proline rich 14-like |
| PRSS8 | protease, serine, 8 |
| RAB3A | RAB3A, member RAS oncogene family |
| RPAP2 | RNA polymerase II associated protein 2 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SFXN1 | sideroflexin 1 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| TMEM104 | transmembrane protein 104 |
| TPCN1 | two pore segment channel 1 |
| TRAIP | TRAF interacting protein |
| TRIM32 | tripartite motif containing 32 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TXLNG | taxilin gamma |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF668 | zinc finger protein 668 |
| ZNF862 | zinc finger protein 862 |
