| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the mefloquine-6205 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ATF3 | activating transcription factor 3 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| ATP7A | ATPase, Cu++ transporting, alpha polypeptide |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C14ORF1 | chromosome 14 open reading frame 1 |
| CCNL1 | cyclin L1 |
| CES1 | carboxylesterase 1 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DSCAM | Down syndrome cell adhesion molecule |
| DUSP1 | dual specificity phosphatase 1 |
| EFNA1 | ephrin-A1 |
| EGR1 | early growth response 1 |
| FGFR3 | fibroblast growth factor receptor 3 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSL1 | FOS-like antigen 1 |
| FOXO3 | forkhead box O3 |
| FZD7 | frizzled class receptor 7 |
| GAD2 | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST1H3B | histone cluster 1, H3b |
| HIST1H4D | histone cluster 1, H4d |
| HMOX1 | heme oxygenase 1 |
| ICAM1 | intercellular adhesion molecule 1 |
| IER2 | immediate early response 2 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFT38 | intraflagellar transport 38 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| ING4 | inhibitor of growth family, member 4 |
| INSIG1 | insulin induced gene 1 |
| JUN | jun proto-oncogene |
| KDM2A | lysine (K)-specific demethylase 2A |
| KIAA1045 | KIAA1045 |
| KLF10 | Kruppel-like factor 10 |
| KLF2 | Kruppel-like factor 2 |
| KLF6 | Kruppel-like factor 6 |
| KLHL22 | kelch-like family member 22 |
| KLHL24 | kelch-like family member 24 |
| LPIN1 | lipin 1 |
| LRRC14 | leucine rich repeat containing 14 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MED15 | mediator complex subunit 15 |
| MEFV | Mediterranean fever |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MT1F | metallothionein 1F |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1X | metallothionein 1X |
| MT2A | metallothionein 2A |
| MVD | mevalonate (diphospho) decarboxylase |
| NCOR2 | nuclear receptor corepressor 2 |
| NEURL1 | neuralized E3 ubiquitin protein ligase 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PCDHB3 | protocadherin beta 3 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| POFUT1 | protein O-fucosyltransferase 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRDM9 | PR domain containing 9 |
| RCAN1 | regulator of calcineurin 1 |
| RGS12 | regulator of G-protein signaling 12 |
| RND1 | Rho family GTPase 1 |
| RNF19B | ring finger protein 19B |
| RUFY3 | RUN and FYVE domain containing 3 |
| SALL2 | spalt-like transcription factor 2 |
| SAP30 | Sin3A-associated protein, 30kDa |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC38A7 | solute carrier family 38, member 7 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TLE4 | transducin-like enhancer of split 4 |
| TMEM63A | transmembrane protein 63A |
| TMPRSS4 | transmembrane protease, serine 4 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TOP3B | topoisomerase (DNA) III beta |
| TRIB3 | tribbles pseudokinase 3 |
| TRIM2 | tripartite motif containing 2 |
| TSPAN9 | tetraspanin 9 |
| TUBGCP3 | tubulin, gamma complex associated protein 3 |
| TXNIP | thioredoxin interacting protein |
| UBA7 | ubiquitin-like modifier activating enzyme 7 |
| ZBTB43 | zinc finger and BTB domain containing 43 |
| ZFP36 | ZFP36 ring finger protein |
| ZNF165 | zinc finger protein 165 |
| ZNF440 | zinc finger protein 440 |
| ZNF589 | zinc finger protein 589 |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ANAPC15 | anaphase promoting complex subunit 15 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| AP3M2 | adaptor-related protein complex 3, mu 2 subunit |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| BATF | basic leucine zipper transcription factor, ATF-like |
| BAX | BCL2-associated X protein |
| BSG | basigin (Ok blood group) |
| C2ORF44 | chromosome 2 open reading frame 44 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CAPG | capping protein (actin filament), gelsolin-like |
| CARD8 | caspase recruitment domain family, member 8 |
| CCDC25 | coiled-coil domain containing 25 |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CEP85 | centrosomal protein 85kDa |
| CHRNA5 | cholinergic receptor, nicotinic, alpha 5 (neuronal) |
| CLDND1 | claudin domain containing 1 |
| COCH | cochlin |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CXORF56 | chromosome X open reading frame 56 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DOLK | dolichol kinase |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
| ERCC6L | excision repair cross-complementation group 6-like |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXO1 | exonuclease 1 |
| FANCC | Fanconi anemia, complementation group C |
| FCHSD2 | FCH and double SH3 domains 2 |
| GLB1L2 | galactosidase, beta 1-like 2 |
| GLI3 | GLI family zinc finger 3 |
| H2AFY2 | H2A histone family, member Y2 |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| HMHA1 | histocompatibility (minor) HA-1 |
| HOMER2 | homer scaffolding protein 2 |
| JADE3 | jade family PHD finger 3 |
| KATNBL1 | katanin p80 subunit B-like 1 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KIF23 | kinesin family member 23 |
| LAMA3 | laminin, alpha 3 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
| LMNB1 | lamin B1 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LOC730101 | uncharacterized LOC730101 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MAGEF1 | melanoma antigen family F1 |
| MAGEH1 | melanoma antigen family H1 |
| MANBA | mannosidase, beta A, lysosomal |
| MCRS1 | microspherule protein 1 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MORC3 | MORC family CW-type zinc finger 3 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| NAA38 | N(alpha)-acetyltransferase 38, NatC auxiliary subunit |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein |
| NMB | neuromedin B |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| NT5C | 5', 3'-nucleotidase, cytosolic |
| PLD3 | phospholipase D family, member 3 |
| POLR3B | polymerase (RNA) III (DNA directed) polypeptide B |
| PP14571 | uncharacterized LOC100130449 |
| PPIP5K2 | diphosphoinositol pentakisphosphate kinase 2 |
| PRMT7 | protein arginine methyltransferase 7 |
| PTCD2 | pentatricopeptide repeat domain 2 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| RRP1 | ribosomal RNA processing 1 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SCAMP4 | secretory carrier membrane protein 4 |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SEH1L | SEH1-like (S. cerevisiae) |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC35A5 | solute carrier family 35, member A5 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SMAD5 | SMAD family member 5 |
| SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 |
| SMU1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) |
| SNUPN | snurportin 1 |
| SSFA2 | sperm specific antigen 2 |
| STBD1 | starch binding domain 1 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| SYNJ2BP | synaptojanin 2 binding protein |
| TAF12 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa |
| TCTN1 | tectonic family member 1 |
| TEAD4 | TEA domain family member 4 |
| TFRC | transferrin receptor |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM134 | transmembrane protein 134 |
| TMEM185B | transmembrane protein 185B |
| TRAPPC13 | trafficking protein particle complex 13 |
| TRIM25 | tripartite motif containing 25 |
| WDR18 | WD repeat domain 18 |
| YEATS4 | YEATS domain containing 4 |
| ZNF787 | zinc finger protein 787 |
| ZNF816 | zinc finger protein 816 |
