megakaryocyte development Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow. (Gene Ontology, GO_0035855)
External Link http://amigo.geneontology.org/amigo/term/GO:0035855
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Genes

11 genes participating in the megakaryocyte development biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
FLNA filamin A, alpha
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GP1BB glycoprotein Ib (platelet), beta polypeptide
GP5 glycoprotein V (platelet)
GP9 glycoprotein IX (platelet)
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
MBD4 methyl-CpG binding domain protein 4
MPIG6B megakaryocyte and platelet inhibitory receptor G6b
SH2B3 SH2B adaptor protein 3
THPO thrombopoietin
ZNF385A zinc finger protein 385A